Zhong F - Search Results

1

Induction of Ca²+-driven apoptosis in chronic lymphocytic leukemia cells by peptide-mediated disruption of Bcl-2-IP3 receptor interaction.

Zhong F, Harr MW, Bultynck G, Monaco G, Parys JB, De Smedt H, Rong YP, Molitoris JK, Lam M, Ryder C, Matsuyama S, Distelhorst CW. Zhong F, et al. Blood. 2011 Mar 10;117(10):2924-34. doi: 10.1182/blood-2010-09-307405. Epub 2010 Dec 30. Blood. 2011. PMID: 21193695 Free PMC article.

2

Dexamethasone-induced gene 2 (dig2) is a novel pro-survival stress gene induced rapidly by diverse apoptotic signals.

Wang Z, Malone MH, Thomenius MJ, Zhong F, Xu F, Distelhorst CW. Wang Z, et al. Among authors: zhong f. J Biol Chem. 2003 Jul 18;278(29):27053-8. doi: 10.1074/jbc.M303723200. Epub 2003 May 7. J Biol Chem. 2003. PMID: 12736248 Free article.

3

Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate.

Chen R, Valencia I, Zhong F, McColl KS, Roderick HL, Bootman MD, Berridge MJ, Conway SJ, Holmes AB, Mignery GA, Velez P, Distelhorst CW. Chen R, et al. Among authors: zhong f. J Cell Biol. 2004 Jul 19;166(2):193-203. doi: 10.1083/jcb.200309146. J Cell Biol. 2004. PMID: 15263017 Free PMC article.

4

Thioredoxin-interacting protein (txnip) is a glucocorticoid-regulated primary response gene involved in mediating glucocorticoid-induced apoptosis.

Wang Z, Rong YP, Malone MH, Davis MC, Zhong F, Distelhorst CW. Wang Z, et al. Among authors: zhong f. Oncogene. 2006 Mar 23;25(13):1903-13. doi: 10.1038/sj.onc.1209218. Oncogene. 2006. PMID: 16301999

5

Bcl-2 differentially regulates Ca2+ signals according to the strength of T cell receptor activation.

Zhong F, Davis MC, McColl KS, Distelhorst CW. Zhong F, et al. J Cell Biol. 2006 Jan 2;172(1):127-37. doi: 10.1083/jcb.200506189. J Cell Biol. 2006. PMID: 16391001 Free PMC article.

6

Dexamethasone-induced inositol 1,4,5-trisphosphate receptor elevation in murine lymphoma cells is not required for dexamethasone-mediated calcium elevation and apoptosis.

Davis MC, McColl KS, Zhong F, Wang Z, Malone MH, Distelhorst CW. Davis MC, et al. Among authors: zhong f. J Biol Chem. 2008 Apr 18;283(16):10357-65. doi: 10.1074/jbc.M800269200. Epub 2008 Feb 13. J Biol Chem. 2008. PMID: 18272518 Free PMC article.

7

Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals.

Rong YP, Aromolaran AS, Bultynck G, Zhong F, Li X, McColl K, Matsuyama S, Herlitze S, Roderick HL, Bootman MD, Mignery GA, Parys JB, De Smedt H, Distelhorst CW. Rong YP, et al. Among authors: zhong f. Mol Cell. 2008 Jul 25;31(2):255-65. doi: 10.1016/j.molcel.2008.06.014. Mol Cell. 2008. PMID: 18657507 Free PMC article.

8

The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor.

Rong YP, Bultynck G, Aromolaran AS, Zhong F, Parys JB, De Smedt H, Mignery GA, Roderick HL, Bootman MD, Distelhorst CW. Rong YP, et al. Among authors: zhong f. Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14397-402. doi: 10.1073/pnas.0907555106. Epub 2009 Aug 17. Proc Natl Acad Sci U S A. 2009. PMID: 19706527 Free PMC article.

9

Inhibition of Lck enhances glucocorticoid sensitivity and apoptosis in lymphoid cell lines and in chronic lymphocytic leukemia.

Harr MW, Caimi PF, McColl KS, Zhong F, Patel SN, Barr PM, Distelhorst CW. Harr MW, et al. Among authors: zhong f. Cell Death Differ. 2010 Sep;17(9):1381-91. doi: 10.1038/cdd.2010.25. Epub 2010 Mar 19. Cell Death Differ. 2010. PMID: 20300113 Free PMC article.

10

Glucocorticoids downregulate Fyn and inhibit IP(3)-mediated calcium signaling to promote autophagy in T lymphocytes.

Harr MW, McColl KS, Zhong F, Molitoris JK, Distelhorst CW. Harr MW, et al. Among authors: zhong f. Autophagy. 2010 Oct;6(7):912-21. doi: 10.4161/auto.6.7.13290. Epub 2010 Oct 2. Autophagy. 2010. PMID: 20814235 Free PMC article.

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