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Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use.
Zhou L, Zuo Z, Chow MS. Zhou L, et al. J Clin Pharmacol. 2005 Dec;45(12):1345-59. doi: 10.1177/0091270005282630. J Clin Pharmacol. 2005. PMID: 16291709 Review.
Improved quality control method for Danshen products--consideration of both hydrophilic and lipophilic active components.
Zhou L, Chow M, Zuo Z. Zhou L, et al. J Pharm Biomed Anal. 2006 Jun 7;41(3):744-50. doi: 10.1016/j.jpba.2005.12.032. Epub 2006 Feb 2. J Pharm Biomed Anal. 2006. PMID: 16458472
Contents of major bioactive flavones in proprietary traditional Chinese medicine products and reference herb of radix Scutellariae.
Li C, Zhou L, Lin G, Zuo Z. Li C, et al. Among authors: zhou l. J Pharm Biomed Anal. 2009 Oct 15;50(3):298-306. doi: 10.1016/j.jpba.2009.04.028. Epub 2009 May 5. J Pharm Biomed Anal. 2009. PMID: 19481403
Effect of sodium caprate on the oral absorptions of danshensu and salvianolic acid B.
Zhou L, Chow MS, Zuo Z. Zhou L, et al. Int J Pharm. 2009 Sep 8;379(1):109-18. doi: 10.1016/j.ijpharm.2009.06.016. Epub 2009 Jun 23. Int J Pharm. 2009. PMID: 19555749
Long-term treatment with danshen-gegen decoction protects the myocardium against ischemia/reperfusion injury via the redox-sensitive protein kinase C-ε/mK(ATP) pathway in rats.
Chiu PY, Wong SM, Leung HY, Leong PK, Chen N, Zhou L, Zuo Z, Lam PY, Ko KM. Chiu PY, et al. Among authors: zhou l. Rejuvenation Res. 2011 Apr;14(2):173-84. doi: 10.1089/rej.2010.1094. Epub 2011 Jan 4. Rejuvenation Res. 2011. PMID: 21204655
Acute treatment with Danshen-Gegen decoction protects the myocardium against ischemia/reperfusion injury via the redox-sensitive PKCɛ/mK(ATP) pathway in rats.
Chiu PY, Wong SM, Leung HY, Leong PK, Chen N, Zhou L, Zuo Z, Lam PY, Ko KM. Chiu PY, et al. Among authors: zhou l. Phytomedicine. 2011 Aug 15;18(11):916-25. doi: 10.1016/j.phymed.2011.03.006. Epub 2011 Apr 29. Phytomedicine. 2011. PMID: 21855786
Danshen-Gegen decoction protects against hypoxia/reoxygenation-induced apoptosis by inhibiting mitochondrial permeability transition via the redox-sensitive ERK/Nrf2 and PKCε/mKATP pathways in H9c2 cardiomyocytes.
Chiu PY, Leung HY, Leong PK, Chen N, Zhou L, Zuo Z, Lam PY, Ko KM. Chiu PY, et al. Among authors: zhou l. Phytomedicine. 2012 Jan 15;19(2):99-110. doi: 10.1016/j.phymed.2011.07.002. Epub 2011 Sep 6. Phytomedicine. 2012. PMID: 21899994
In vitro and in situ evaluation of herb-drug interactions during intestinal metabolism and absorption of baicalein.
Fong YK, Li CR, Wo SK, Wang S, Zhou L, Zhang L, Lin G, Zuo Z. Fong YK, et al. Among authors: zhou l. J Ethnopharmacol. 2012 Jun 1;141(2):742-53. doi: 10.1016/j.jep.2011.08.042. Epub 2011 Aug 26. J Ethnopharmacol. 2012. PMID: 21906668
Pharmacokinetic and pharmacodynamic interaction of Danshen-Gegen extract with warfarin and aspirin.
Zhou L, Wang S, Zhang Z, Lau BS, Fung KP, Leung PC, Zuo Z. Zhou L, et al. J Ethnopharmacol. 2012 Sep 28;143(2):648-55. doi: 10.1016/j.jep.2012.07.029. Epub 2012 Jul 31. J Ethnopharmacol. 2012. PMID: 22867637
Induction of liver cytochrome P450s by Danshen-Gegen formula is the leading cause for its pharmacokinetic interactions with warfarin.
Zhang Z, Ge B, Zhou L, Lam TN, Zuo Z. Zhang Z, et al. Among authors: zhou l. J Ethnopharmacol. 2014 Jul 3;154(3):672-86. doi: 10.1016/j.jep.2014.04.047. Epub 2014 May 14. J Ethnopharmacol. 2014. PMID: 24832110
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