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Structure of a type IV CRISPR-Cas ribonucleoprotein complex.
Zhou Y, Bravo JPK, Taylor HN, Steens JA, Jackson RN, Staals RHJ, Taylor DW. Zhou Y, et al. iScience. 2021 Feb 17;24(3):102201. doi: 10.1016/j.isci.2021.102201. eCollection 2021 Mar 19. iScience. 2021. PMID: 33733066 Free PMC article.
Supercharging enables organized assembly of synthetic biomolecules.
Simon AJ, Zhou Y, Ramasubramani V, Glaser J, Pothukuchy A, Gollihar J, Gerberich JC, Leggere JC, Morrow BR, Jung C, Glotzer SC, Taylor DW, Ellington AD. Simon AJ, et al. Among authors: zhou y. Nat Chem. 2019 Mar;11(3):204-212. doi: 10.1038/s41557-018-0196-3. Epub 2019 Jan 14. Nat Chem. 2019. PMID: 30643229
The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies.
Copin R, Baum A, Wloga E, Pascal KE, Giordano S, Fulton BO, Zhou A, Negron N, Lanza K, Chan N, Coppola A, Chiu J, Ni M, Wei Y, Atwal GS, Hernandez AR, Saotome K, Zhou Y, Franklin MC, Hooper AT, McCarthy S, Hamon S, Hamilton JD, Staples HM, Alfson K, Carrion R Jr, Ali S, Norton T, Somersan-Karakaya S, Sivapalasingam S, Herman GA, Weinreich DM, Lipsich L, Stahl N, Murphy AJ, Yancopoulos GD, Kyratsous CA. Copin R, et al. Among authors: zhou y, zhou a. Cell. 2021 Jul 22;184(15):3949-3961.e11. doi: 10.1016/j.cell.2021.06.002. Epub 2021 Jun 5. Cell. 2021. PMID: 34161776 Free PMC article. Clinical Trial.
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