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Inhibitory effects of fatty acids on glucose-regulated B-cell function: association with increased islet triglyceride stores and altered effect of fatty acid oxidation on glucose metabolism.
Zhou YP, Ling ZC, Grill VE. Zhou YP, et al. Metabolism. 1996 Aug;45(8):981-6. doi: 10.1016/s0026-0495(96)90267-x. Metabolism. 1996. PMID: 8769356
Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes.
Mahdi T, Hänzelmann S, Salehi A, Muhammed SJ, Reinbothe TM, Tang Y, Axelsson AS, Zhou Y, Jing X, Almgren P, Krus U, Taneera J, Blom AM, Lyssenko V, Esguerra JL, Hansson O, Eliasson L, Derry J, Zhang E, Wollheim CB, Groop L, Renström E, Rosengren AH. Mahdi T, et al. Cell Metab. 2012 Nov 7;16(5):625-33. doi: 10.1016/j.cmet.2012.10.009. Cell Metab. 2012. PMID: 23140642
Insulin mediators in man: effects of glucose ingestion and insulin resistance.
Shashkin PN, Shashkina EF, Fernqvist-Forbes E, Zhou YP, Grill V, Katz A. Shashkin PN, et al. Among authors: zhou yp. Diabetologia. 1997 May;40(5):557-63. doi: 10.1007/s001250050715. Diabetologia. 1997. PMID: 9165224
Fasting and decreased B cell sensitivity: important role for fatty acid-induced inhibition of PDH activity.
Zhou YP, Priestman DA, Randle PJ, Grill VE. Zhou YP, et al. Am J Physiol. 1996 Jun;270(6 Pt 1):E988-94. doi: 10.1152/ajpendo.1996.270.6.E988. Am J Physiol. 1996. PMID: 8764183
A fatty acid-induced decrease in pyruvate dehydrogenase activity is an important determinant of beta-cell dysfunction in the obese diabetic db/db mouse.
Zhou YP, Berggren PO, Grill V. Zhou YP, et al. Diabetes. 1996 May;45(5):580-6. doi: 10.2337/diab.45.5.580. Diabetes. 1996. PMID: 8621007
Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle.
Zhou YP, Grill VE. Zhou YP, et al. J Clin Invest. 1994 Feb;93(2):870-6. doi: 10.1172/JCI117042. J Clin Invest. 1994. PMID: 8113418 Free PMC article.
Long term exposure to fatty acids and ketones inhibits B-cell functions in human pancreatic islets of Langerhans.
Zhou YP, Grill V. Zhou YP, et al. J Clin Endocrinol Metab. 1995 May;80(5):1584-90. doi: 10.1210/jcem.80.5.7745004. J Clin Endocrinol Metab. 1995. PMID: 7745004
Deficiency of pyruvate dehydrogenase activity in pancreatic islets of diabetic GK rats.
Zhou YP, Ostenson CG, Ling ZC, Grill V. Zhou YP, et al. Endocrinology. 1995 Aug;136(8):3546-51. doi: 10.1210/endo.136.8.7628391. Endocrinology. 1995. PMID: 7628391
Palmitate-induced beta-cell insensitivity to glucose is coupled to decreased pyruvate dehydrogenase activity and enhanced kinase activity in rat pancreatic islets.
Zhou YP, Grill VE. Zhou YP, et al. Diabetes. 1995 Apr;44(4):394-9. doi: 10.2337/diab.44.4.394. Diabetes. 1995. PMID: 7698506
Apoptosis in insulin-secreting cells. Evidence for the role of intracellular Ca2+ stores and arachidonic acid metabolism.
Zhou YP, Teng D, Dralyuk F, Ostrega D, Roe MW, Philipson L, Polonsky KS. Zhou YP, et al. J Clin Invest. 1998 Apr 15;101(8):1623-32. doi: 10.1172/JCI1245. J Clin Invest. 1998. PMID: 9541492 Free PMC article.
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