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Depletion of intracellular glutathione contributes to JNK-mediated death receptor 5 upregulation and apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me).
Yue P, Zhou Z, Khuri FR, Sun SY. Yue P, et al. Among authors: zhou z. Cancer Biol Ther. 2006 May;5(5):492-7. doi: 10.4161/cbt.5.5.2565. Epub 2006 May 2. Cancer Biol Ther. 2006. PMID: 16582599
A new oridonin analog suppresses triple-negative breast cancer cells and tumor growth via the induction of death receptor 5.
Wu J, Ding Y, Chen CH, Zhou Z, Ding C, Chen H, Zhou J, Chen C. Wu J, et al. Among authors: zhou z, zhou j. Cancer Lett. 2016 Oct 1;380(2):393-402. doi: 10.1016/j.canlet.2016.06.024. Epub 2016 Jul 4. Cancer Lett. 2016. PMID: 27387452
Assessment of apoptosis-inducing effects of docetaxel combined with the proteasome inhibitor PS-341 in human lung cancer cells.
Jung CS, Zhou Z, Khuri FR, Sun SY. Jung CS, et al. Among authors: zhou z. Cancer Biol Ther. 2007 May;6(5):749-54. doi: 10.4161/cbt.6.5.3977. Epub 2007 Feb 7. Cancer Biol Ther. 2007. PMID: 17387269
Vitamin C inactivates the proteasome inhibitor PS-341 in human cancer cells.
Zou W, Yue P, Lin N, He M, Zhou Z, Lonial S, Khuri FR, Wang B, Sun SY. Zou W, et al. Among authors: zhou z. Clin Cancer Res. 2006 Jan 1;12(1):273-80. doi: 10.1158/1078-0432.CCR-05-0503. Clin Cancer Res. 2006. PMID: 16397052
KLF5 promotes cell proliferation and tumorigenesis through gene regulation and the TSU-Pr1 human bladder cancer cell line.
Chen C, Benjamin MS, Sun X, Otto KB, Guo P, Dong XY, Bao Y, Zhou Z, Cheng X, Simons JW, Dong JT. Chen C, et al. Among authors: zhou z. Int J Cancer. 2006 Mar 15;118(6):1346-55. doi: 10.1002/ijc.21533. Int J Cancer. 2006. PMID: 16184550
Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition.
Sun SY, Rosenberg LM, Wang X, Zhou Z, Yue P, Fu H, Khuri FR. Sun SY, et al. Among authors: zhou z. Cancer Res. 2005 Aug 15;65(16):7052-8. doi: 10.1158/0008-5472.CAN-05-0917. Cancer Res. 2005. PMID: 16103051
Activation of nuclear factor-kappaB contributes to induction of death receptors and apoptosis by the synthetic retinoid CD437 in DU145 human prostate cancer cells.
Jin F, Liu X, Zhou Z, Yue P, Lotan R, Khuri FR, Chung LW, Sun SY. Jin F, et al. Among authors: zhou z. Cancer Res. 2005 Jul 15;65(14):6354-63. doi: 10.1158/0008-5472.CAN-04-4061. Cancer Res. 2005. PMID: 16024638
Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells.
Liu X, Yue P, Zhou Z, Khuri FR, Sun SY. Liu X, et al. Among authors: zhou z. J Natl Cancer Inst. 2004 Dec 1;96(23):1769-80. doi: 10.1093/jnci/djh322. J Natl Cancer Inst. 2004. PMID: 15572759
c-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3,12-dioxooleana-1, 9-dien-28-oate in human lung cancer cells.
Zou W, Liu X, Yue P, Zhou Z, Sporn MB, Lotan R, Khuri FR, Sun SY. Zou W, et al. Among authors: zhou z. Cancer Res. 2004 Oct 15;64(20):7570-8. doi: 10.1158/0008-5472.CAN-04-1238. Cancer Res. 2004. PMID: 15492284
The farnesyltransferase inhibitor Lonafarnib induces growth arrest or apoptosis of human lung cancer cells without downregulation of Akt.
Sun SY, Zhou Z, Wang R, Fu H, Khuri FR. Sun SY, et al. Among authors: zhou z. Cancer Biol Ther. 2004 Nov;3(11):1092-8; discussion 1099-1101. doi: 10.4161/cbt.3.11.1176. Epub 2004 Nov 12. Cancer Biol Ther. 2004. PMID: 15467440
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