Zhu M - Search Results

1

High-throughput screening and characterization of reactive metabolites using polarity switching of hybrid triple quadrupole linear ion trap mass spectrometry.

Wen B, Ma L, Nelson SD, Zhu M. Wen B, et al. Among authors: zhu m. Anal Chem. 2008 Mar 1;80(5):1788-99. doi: 10.1021/ac702232r. Epub 2008 Feb 6. Anal Chem. 2008. PMID: 18251522

2

Protein covalent binding of maxipost through a cytochrome P450-mediated ortho-quinone methide intermediate in rats.

Zhang D, Ogan M, Gedamke R, Roongta V, Dai R, Zhu M, Rinehart JK, Klunk L, Mitroka J. Zhang D, et al. Among authors: zhu m. Drug Metab Dispos. 2003 Jul;31(7):837-45. doi: 10.1124/dmd.31.7.837. Drug Metab Dispos. 2003. PMID: 12814959

3

A rapid and sensitive LC/MS/MS assay for quantitative determination of digoxin in rat plasma.

Yao M, Zhang H, Chong S, Zhu M, Morrison RA. Yao M, et al. Among authors: zhu m. J Pharm Biomed Anal. 2003 Aug 21;32(6):1189-97. doi: 10.1016/s0731-7085(03)00050-5. J Pharm Biomed Anal. 2003. PMID: 12907263

4

A strategy for metabolite identification using triple-quadrupole mass spectrometry with enhanced resolution and accurate mass capability.

Jemal M, Ouyang Z, Zhao W, Zhu M, Wu WW. Jemal M, et al. Among authors: zhu m. Rapid Commun Mass Spectrom. 2003;17(24):2732-40. doi: 10.1002/rcm.1256. Rapid Commun Mass Spectrom. 2003. PMID: 14673820

5

Discovering drugs through biological transformation: role of pharmacologically active metabolites in drug discovery.

Fura A, Shu YZ, Zhu M, Hanson RL, Roongta V, Humphreys WG. Fura A, et al. Among authors: zhu m. J Med Chem. 2004 Aug 26;47(18):4339-51. doi: 10.1021/jm040066v. J Med Chem. 2004. PMID: 15317447 Review. No abstract available.

6

Cyp2D6 catalyzes 5-hydroxylation of 1-(2-pyrimidinyl)-piperazine, an active metabolite of several psychoactive drugs, in human liver microsomes.

Raghavan N, Zhang D, Zhu M, Zeng J, Christopher L. Raghavan N, et al. Among authors: zhu m. Drug Metab Dispos. 2005 Feb;33(2):203-8. doi: 10.1124/dmd.104.001198. Epub 2004 Oct 26. Drug Metab Dispos. 2005. PMID: 15507542

7

Analysis of low level radioactive metabolites in biological fluids using high-performance liquid chromatography with microplate scintillation counting: method validation and application.

Zhu M, Zhao W, Vazquez N, Mitroka JG. Zhu M, et al. J Pharm Biomed Anal. 2005 Sep 1;39(1-2):233-45. doi: 10.1016/j.jpba.2005.03.012. J Pharm Biomed Anal. 2005. PMID: 15899570

8

A novel high-throughput automated chip-based nanoelectrospray tandem mass spectrometric method for PAMPA sample analysis.

Balimane PV, Pace E, Chong S, Zhu M, Jemal M, Pelt CK. Balimane PV, et al. Among authors: zhu m. J Pharm Biomed Anal. 2005 Sep 1;39(1-2):8-16. doi: 10.1016/j.jpba.2005.03.043. J Pharm Biomed Anal. 2005. PMID: 15978768

9

Structural elucidation of human oxidative metabolites of muraglitazar: use of microbial bioreactors in the biosynthesis of metabolite standards.

Zhang D, Zhang H, Aranibar N, Hanson R, Huang Y, Cheng PT, Wu S, Bonacorsi S, Zhu M, Swaminathan A, Humphreys WG. Zhang D, et al. Among authors: zhu m. Drug Metab Dispos. 2006 Feb;34(2):267-80. doi: 10.1124/dmd.105.007153. Epub 2005 Nov 9. Drug Metab Dispos. 2006. PMID: 16280454 Clinical Trial.

10

Detection and characterization of metabolites in biological matrices using mass defect filtering of liquid chromatography/high resolution mass spectrometry data.

Zhu M, Ma L, Zhang D, Ray K, Zhao W, Humphreys WG, Skiles G, Sanders M, Zhang H. Zhu M, et al. Drug Metab Dispos. 2006 Oct;34(10):1722-33. doi: 10.1124/dmd.106.009241. Epub 2006 Jun 30. Drug Metab Dispos. 2006. PMID: 16815965

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