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TSC2 mediates cellular energy response to control cell growth and survival.
Inoki K, Zhu T, Guan KL. Inoki K, et al. Among authors: zhu t. Cell. 2003 Nov 26;115(5):577-90. doi: 10.1016/s0092-8674(03)00929-2. Cell. 2003. PMID: 14651849
Transformation potential of Ras isoforms correlates with activation of phosphatidylinositol 3-kinase but not ERK.
Li W, Zhu T, Guan KL. Li W, et al. Among authors: zhu t. J Biol Chem. 2004 Sep 3;279(36):37398-406. doi: 10.1074/jbc.M405730200. Epub 2004 Jun 21. J Biol Chem. 2004. PMID: 15210703 Retracted.
TSC1 stabilizes TSC2 by inhibiting the interaction between TSC2 and the HERC1 ubiquitin ligase.
Chong-Kopera H, Inoki K, Li Y, Zhu T, Garcia-Gonzalo FR, Rosa JL, Guan KL. Chong-Kopera H, et al. Among authors: zhu t. J Biol Chem. 2006 Mar 31;281(13):8313-6. doi: 10.1074/jbc.C500451200. Epub 2006 Feb 7. J Biol Chem. 2006. PMID: 16464865
TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth.
Inoki K, Ouyang H, Zhu T, Lindvall C, Wang Y, Zhang X, Yang Q, Bennett C, Harada Y, Stankunas K, Wang CY, He X, MacDougald OA, You M, Williams BO, Guan KL. Inoki K, et al. Among authors: zhu t. Cell. 2006 Sep 8;126(5):955-68. doi: 10.1016/j.cell.2006.06.055. Cell. 2006. PMID: 16959574
Yap1 protein regulates vascular smooth muscle cell phenotypic switch by interaction with myocardin.
Xie C, Guo Y, Zhu T, Zhang J, Ma PX, Chen YE. Xie C, et al. Among authors: zhu t. J Biol Chem. 2012 Apr 27;287(18):14598-605. doi: 10.1074/jbc.M111.329268. Epub 2012 Mar 12. J Biol Chem. 2012. PMID: 22411986 Free PMC article.
Effective gene targeting in rabbits using RNA-guided Cas9 nucleases.
Yang D, Xu J, Zhu T, Fan J, Lai L, Zhang J, Chen YE. Yang D, et al. Among authors: zhu t. J Mol Cell Biol. 2014 Feb;6(1):97-9. doi: 10.1093/jmcb/mjt047. Epub 2014 Jan 8. J Mol Cell Biol. 2014. PMID: 24403564 Free PMC article. No abstract available.
Yes-Associated Protein Inhibits Transcription of Myocardin and Attenuates Differentiation of Vascular Smooth Muscle Cell from Cardiovascular Progenitor Cell Lineage.
Wang L, Qiu P, Jiao J, Hirai H, Xiong W, Zhang J, Zhu T, Ma PX, Chen YE, Yang B. Wang L, et al. Among authors: zhu t. Stem Cells. 2017 Feb;35(2):351-361. doi: 10.1002/stem.2484. Epub 2016 Sep 20. Stem Cells. 2017. PMID: 27571517 Free PMC article.
Endothelial TFEB (Transcription Factor EB) Positively Regulates Postischemic Angiogenesis.
Fan Y, Lu H, Liang W, Garcia-Barrio MT, Guo Y, Zhang J, Zhu T, Hao Y, Zhang J, Chen YE. Fan Y, et al. Among authors: zhu t. Circ Res. 2018 Mar 30;122(7):945-957. doi: 10.1161/CIRCRESAHA.118.312672. Epub 2018 Feb 21. Circ Res. 2018. PMID: 29467198 Free PMC article.
Single cell RNA sequencing reveals the cellular heterogeneity of aneurysmal infrarenal abdominal aorta.
Zhao G, Lu H, Chang Z, Zhao Y, Zhu T, Chang L, Guo Y, Garcia-Barrio MT, Chen YE, Zhang J. Zhao G, et al. Among authors: zhu t. Cardiovasc Res. 2020 Jul 17:cvaa214. doi: 10.1093/cvr/cvaa214. Online ahead of print. Cardiovasc Res. 2020. PMID: 32678909
Unbiased clustering analysis of the transcriptional profiles from >4500 aortic cells identified 17 clusters representing 9 cell lineages, encompassing vascular smooth muscle cells, fibroblasts, endothelial cells, immune cells (macrophages, T cells, B cells and dendritic …
Unbiased clustering analysis of the transcriptional profiles from >4500 aortic cells identified 17 clusters representing 9 cell lineages, …
Deficiency of Cholesteryl Ester Transfer Protein Protects Against Atherosclerosis in Rabbits.
Zhang J, Niimi M, Yang D, Liang J, Xu J, Kimura T, Mathew AV, Guo Y, Fan Y, Zhu T, Song J, Ackermann R, Koike Y, Schwendeman A, Lai L, Pennathur S, Garcia-Barrio M, Fan J, Chen YE. Zhang J, et al. Among authors: zhu t. Arterioscler Thromb Vasc Biol. 2017 Jun;37(6):1068-1075. doi: 10.1161/ATVBAHA.117.309114. Epub 2017 Apr 20. Arterioscler Thromb Vasc Biol. 2017. PMID: 28428219 Free PMC article.
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