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New knowledge of the mechanisms of sorafenib resistance in liver cancer.
Zhu YJ, Zheng B, Wang HY, Chen L. Zhu YJ, et al. Acta Pharmacol Sin. 2017 May;38(5):614-622. doi: 10.1038/aps.2017.5. Epub 2017 Mar 27. Acta Pharmacol Sin. 2017. PMID: 28344323 Free PMC article. Review.
Aldehyde dehydrogenase-2 (ALDH2) opposes hepatocellular carcinoma progression by regulating AMP-activated protein kinase signaling in mice.
Hou G, Chen L, Liu G, Li L, Yang Y, Yan HX, Zhang HL, Tang J, Yang YC, Lin X, Chen X, Luo GJ, Zhu Y, Tang S, Zhang J, Liu H, Gu Q, Zhao LH, Li Y, Liu L, Zhou W, Wang H. Hou G, et al. Hepatology. 2017 May;65(5):1628-1644. doi: 10.1002/hep.29006. Epub 2017 Mar 31. Hepatology. 2017. PMID: 28027570
Choline Kinase α Mediates Interactions Between the Epidermal Growth Factor Receptor and Mechanistic Target of Rapamycin Complex 2 in Hepatocellular Carcinoma Cells to Promote Drug Resistance and Xenograft Tumor Progression.
Lin XM, Hu L, Gu J, Wang RY, Li L, Tang J, Zhang BH, Yan XZ, Zhu YJ, Hu CL, Zhou WP, Li S, Liu JF, Gonzalez FJ, Wu MC, Wang HY, Chen L. Lin XM, et al. Gastroenterology. 2017 Apr;152(5):1187-1202. doi: 10.1053/j.gastro.2016.12.033. Epub 2017 Jan 5. Gastroenterology. 2017. PMID: 28065789 Free PMC article.
Gender disparity in hepatocellular carcinoma (HCC): multiple underlying mechanisms.
Zheng B, Zhu YJ, Wang HY, Chen L. Zheng B, et al. Sci China Life Sci. 2017 Jun;60(6):575-584. doi: 10.1007/s11427-016-9043-9. Epub 2017 May 23. Sci China Life Sci. 2017. PMID: 28547581 Review.
Circular RNAs negatively regulate cancer stem cells by physically binding FMRP against CCAR1 complex in hepatocellular carcinoma.
Zhu YJ, Zheng B, Luo GJ, Ma XK, Lu XY, Lin XM, Yang S, Zhao Q, Wu T, Li ZX, Liu XL, Wu R, Liu JF, Ge Y, Yang L, Wang HY, Chen L. Zhu YJ, et al. Theranostics. 2019 May 26;9(12):3526-3540. doi: 10.7150/thno.32796. eCollection 2019. Theranostics. 2019. PMID: 31281495 Free PMC article.
Integrative molecular analysis of metastatic hepatocellular carcinoma.
Wang D, Zhu Y, Tang J, Lian Q, Luo G, Wen W, Zhang MQ, Wang H, Chen L, Gu J. Wang D, et al. BMC Med Genomics. 2019 Nov 13;12(1):164. doi: 10.1186/s12920-019-0586-4. BMC Med Genomics. 2019. PMID: 31722693 Free PMC article.
Targeted sequencing reveals the mutational landscape responsible for sorafenib therapy in advanced hepatocellular carcinoma.
Tang J, Sui CJ, Wang DF, Lu XY, Luo GJ, Zhao Q, Lian QY, Jeong S, Lin XM, Zhu YJ, Zheng B, Wu R, Wang Q, Liu XL, Liu JF, Xia Q, Wu G, Gu J, Wang HY, Chen L. Tang J, et al. Theranostics. 2020 Apr 6;10(12):5384-5397. doi: 10.7150/thno.41616. eCollection 2020. Theranostics. 2020. PMID: 32373219 Free PMC article.
Genome-wide mapping of 5-hydroxymethylcytosines in circulating cell-free DNA as a non-invasive approach for early detection of hepatocellular carcinoma.
Cai J, Chen L, Zhang Z, Zhang X, Lu X, Liu W, Shi G, Ge Y, Gao P, Yang Y, Ke A, Xiao L, Dong R, Zhu Y, Yang X, Wang J, Zhu T, Yang D, Huang X, Sui C, Qiu S, Shen F, Sun H, Zhou W, Zhou J, Nie J, Zeng C, Stroup EK, Zhang X, Chiu BC, Lau WY, He C, Wang H, Zhang W, Fan J. Cai J, et al. Gut. 2019 Dec;68(12):2195-2205. doi: 10.1136/gutjnl-2019-318882. Epub 2019 Jul 29. Gut. 2019. PMID: 31358576 Free PMC article. Clinical Trial.
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