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Inhibition of protein phosphatase 2A with a small molecule LB100 radiosensitizes nasopharyngeal carcinoma xenografts by inducing mitotic catastrophe and blocking DNA damage repair.
Lv P, Wang Y, Ma J, Wang Z, Li JL, Hong CS, Zhuang Z, Zeng YX. Lv P, et al. Among authors: zhuang z. Oncotarget. 2014 Sep 15;5(17):7512-24. doi: 10.18632/oncotarget.2258. Oncotarget. 2014. Retraction in: Oncotarget. 2025 May 19;16:361. doi: 10.18632/oncotarget.28727. PMID: 25245035 Free PMC article. Retracted.
Protein Phosphatase 2A Inhibition with LB100 Enhances Radiation-Induced Mitotic Catastrophe and Tumor Growth Delay in Glioblastoma.
Gordon IK, Lu J, Graves CA, Huntoon K, Frerich JM, Hanson RH, Wang X, Hong CS, Ho W, Feldman MJ, Ikejiri B, Bisht K, Chen XS, Tandle A, Yang C, Arscott WT, Ye D, Heiss JD, Lonser RR, Camphausen K, Zhuang Z. Gordon IK, et al. Among authors: zhuang z. Mol Cancer Ther. 2015 Jul;14(7):1540-1547. doi: 10.1158/1535-7163.MCT-14-0614. Epub 2015 May 4. Mol Cancer Ther. 2015. PMID: 25939762 Free PMC article.
Novel Targeting of Transcription and Metabolism in Glioblastoma.
Su YT, Chen R, Wang H, Song H, Zhang Q, Chen LY, Lappin H, Vasconcelos G, Lita A, Maric D, Li A, Celiku O, Zhang W, Meetze K, Estok T, Larion M, Abu-Asab M, Zhuang Z, Yang C, Gilbert MR, Wu J. Su YT, et al. Among authors: zhuang z. Clin Cancer Res. 2018 Mar 1;24(5):1124-1137. doi: 10.1158/1078-0432.CCR-17-2032. Epub 2017 Dec 18. Clin Cancer Res. 2018. PMID: 29254993 Free PMC article.
3,578 results