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164 results
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Page 1
Microglia-Neutrophil Interactions Drive Dry AMD-like Pathology in a Mouse Model.
Boyce M, Xin Y, Chowdhury O, Shang P, Liu H, Koontz V, Strizhakova A, Nemani M, Hose S, Zigler JS Jr, Campbell M, Sinha D, Handa JT, Kaarniranta K, Qian J, Ghosh S. Boyce M, et al. Among authors: zigler js jr. Cells. 2022 Nov 9;11(22):3535. doi: 10.3390/cells11223535. Cells. 2022. PMID: 36428965 Free article.
Reducing Akt2 in retinal pigment epithelial cells causes a compensatory increase in Akt1 and attenuates diabetic retinopathy.
Liu H, Stepicheva NA, Ghosh S, Shang P, Chowdhury O, Daley RA, Yazdankhah M, Gupta U, Hose SL, Valapala M, Fitting CS, Strizhakova A, Shan Y, Feenstra D, Sahel JA, Jayagopal A, Handa JT, Zigler JS Jr, Fort PE, Sodhi A, Sinha D. Liu H, et al. Among authors: zigler js jr. Nat Commun. 2022 Oct 13;13(1):6045. doi: 10.1038/s41467-022-33773-0. Nat Commun. 2022. PMID: 36229454 Free PMC article.
Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD.
Gupta U, Ghosh S, Wallace CT, Shang P, Xin Y, Nair AP, Yazdankhah M, Strizhakova A, Ross MA, Liu H, Hose S, Stepicheva NA, Chowdhury O, Nemani M, Maddipatla V, Grebe R, Das M, Lathrop KL, Sahel JA, Zigler JS Jr, Qian J, Ghosh A, Sergeev Y, Handa JT, St Croix CM, Sinha D. Gupta U, et al. Among authors: zigler js jr. Autophagy. 2022 Apr 26:1-20. doi: 10.1080/15548627.2022.2062887. Online ahead of print. Autophagy. 2022. PMID: 35473441
βA1-crystallin regulates glucose metabolism and mitochondrial function in mouse retinal astrocytes by modulating PTP1B activity.
Ghosh S, Liu H, Yazdankhah M, Stepicheva N, Shang P, Vaidya T, Hose S, Gupta U, Calderon MJ, Hu MW, Nair AP, Weiss J, Fitting CS, Bhutto IA, Gadde SGK, Naik NK, Jaydev C, Lutty GA, Handa JT, Jayagopal A, Qian J, Sahel JA, Rajasundaram D, Sergeev Y, Zigler JS Jr, Sethu S, Watkins S, Ghosh A, Sinha D. Ghosh S, et al. Among authors: zigler js jr. Commun Biol. 2021 Feb 24;4(1):248. doi: 10.1038/s42003-021-01763-5. Commun Biol. 2021. PMID: 33627831 Free PMC article.
BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes.
Yazdankhah M, Ghosh S, Shang P, Stepicheva N, Hose S, Liu H, Chamling X, Tian S, Sullivan MLG, Calderon MJ, Fitting CS, Weiss J, Jayagopal A, Handa JT, Sahel JA, Zigler JS Jr, Kinchington PR, Zack DJ, Sinha D. Yazdankhah M, et al. Among authors: zigler js jr. Autophagy. 2021 Oct;17(10):3140-3159. doi: 10.1080/15548627.2020.1871204. Epub 2021 Jan 19. Autophagy. 2021. PMID: 33404293 Free PMC article.
Role of glia in optic nerve.
Yazdankhah M, Shang P, Ghosh S, Hose S, Liu H, Weiss J, Fitting CS, Bhutto IA, Zigler JS Jr, Qian J, Sahel JA, Sinha D, Stepicheva NA. Yazdankhah M, et al. Among authors: zigler js jr. Prog Retin Eye Res. 2021 Mar;81:100886. doi: 10.1016/j.preteyeres.2020.100886. Epub 2020 Aug 6. Prog Retin Eye Res. 2021. PMID: 32771538 Free PMC article. Review.
The role of lipocalin-2 in age-related macular degeneration (AMD).
Ghosh S, Stepicheva N, Yazdankhah M, Shang P, Watson AM, Hose S, Liu H, Weiss J, Zigler JS Jr, Valapala M, Watkins SC, Sinha D. Ghosh S, et al. Among authors: zigler js jr. Cell Mol Life Sci. 2020 Mar;77(5):835-851. doi: 10.1007/s00018-019-03423-8. Epub 2020 Jan 4. Cell Mol Life Sci. 2020. PMID: 31901947 Free PMC article. Review.
Neutrophils homing into the retina trigger pathology in early age-related macular degeneration.
Ghosh S, Padmanabhan A, Vaidya T, Watson AM, Bhutto IA, Hose S, Shang P, Stepicheva N, Yazdankhah M, Weiss J, Das M, Gopikrishna S, Aishwarya, Yadav N, Berger T, Mak TW, Xia S, Qian J, Lutty GA, Jayagopal A, Zigler JS Jr, Sethu S, Handa JT, Watkins SC, Ghosh A, Sinha D. Ghosh S, et al. Among authors: zigler js jr. Commun Biol. 2019 Sep 20;2:348. doi: 10.1038/s42003-019-0588-y. eCollection 2019. Commun Biol. 2019. PMID: 31552301 Free PMC article.
164 results