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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor.
Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS, Anderson MJ, Arden KC, Blenis J, Greenberg ME. Brunet A, et al. Cell. 1999 Mar 19;96(6):857-68. doi: 10.1016/s0092-8674(00)80595-4. Cell. 1999. PMID: 10102273
GST P1, a novel downstream regulator of LRRK2, G2019S-induced neuronal cell death.
Chen J, Liou A, Zhang L, Weng Z, Gao Y, Cao G, Zigmond MJ, Chen J. Chen J, et al. Front Biosci (Elite Ed). 2012 Jun 1;4:2365-77. doi: 10.2741/e548. Front Biosci (Elite Ed). 2012. PMID: 22652643 Free PMC article.
Wild-type LRRK2 but not its mutant attenuates stress-induced cell death via ERK pathway.
Liou AK, Leak RK, Li L, Zigmond MJ. Liou AK, et al. Neurobiol Dis. 2008 Oct;32(1):116-24. doi: 10.1016/j.nbd.2008.06.016. Epub 2008 Jul 8. Neurobiol Dis. 2008. PMID: 18675914 Free PMC article.
Protective effects and mechanisms of sirtuins in the nervous system.
Zhang F, Wang S, Gan L, Vosler PS, Gao Y, Zigmond MJ, Chen J. Zhang F, et al. Prog Neurobiol. 2011 Nov;95(3):373-95. doi: 10.1016/j.pneurobio.2011.09.001. Epub 2011 Sep 10. Prog Neurobiol. 2011. PMID: 21930182 Free PMC article. Review.
Preconditioning provides neuroprotection in models of CNS disease: paradigms and clinical significance.
Stetler RA, Leak RK, Gan Y, Li P, Zhang F, Hu X, Jing Z, Chen J, Zigmond MJ, Gao Y. Stetler RA, et al. Prog Neurobiol. 2014 Mar;114:58-83. doi: 10.1016/j.pneurobio.2013.11.005. Epub 2014 Jan 2. Prog Neurobiol. 2014. PMID: 24389580 Free PMC article. Review.
Adaptation to chronic MG132 reduces oxidative toxicity by a CuZnSOD-dependent mechanism.
Leak RK, Zigmond MJ, Liou AK. Leak RK, et al. J Neurochem. 2008 Jul;106(2):860-74. doi: 10.1111/j.1471-4159.2008.05459.x. Epub 2008 May 3. J Neurochem. 2008. PMID: 18466318 Free PMC article.
Role of ERK1, 2, and 5 in dopamine neuron survival during aging.
Parmar MS, Jaumotte JD, Wyrostek SL, Zigmond MJ, Cavanaugh JE. Parmar MS, et al. Among authors: zigmond mj. Neurobiol Aging. 2014 Mar;35(3):669-79. doi: 10.1016/j.neurobiolaging.2013.09.031. Epub 2013 Oct 23. Neurobiol Aging. 2014. PMID: 24411019 Free PMC article.
Triggering endogenous neuroprotective processes through exercise in models of dopamine deficiency.
Zigmond MJ, Cameron JL, Leak RK, Mirnics K, Russell VA, Smeyne RJ, Smith AD. Zigmond MJ, et al. Parkinsonism Relat Disord. 2009 Dec;15 Suppl 3:S42-5. doi: 10.1016/S1353-8020(09)70778-3. Parkinsonism Relat Disord. 2009. PMID: 20083005
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