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Peripheral cannabinoid receptor, CB2, regulates bone mass.
Ofek O, Karsak M, Leclerc N, Fogel M, Frenkel B, Wright K, Tam J, Attar-Namdar M, Kram V, Shohami E, Mechoulam R, Zimmer A, Bab I. Ofek O, et al. Among authors: zimmer a. Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):696-701. doi: 10.1073/pnas.0504187103. Epub 2006 Jan 9. Proc Natl Acad Sci U S A. 2006. PMID: 16407142 Free PMC article.
The major central endocannabinoid directly acts at GABA(A) receptors.
Sigel E, Baur R, Rácz I, Marazzi J, Smart TG, Zimmer A, Gertsch J. Sigel E, et al. Among authors: zimmer a. Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):18150-5. doi: 10.1073/pnas.1113444108. Epub 2011 Oct 24. Proc Natl Acad Sci U S A. 2011. PMID: 22025726 Free PMC article.
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