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The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.
Franklin BS, Bossaller L, De Nardo D, Ratter JM, Stutz A, Engels G, Brenker C, Nordhoff M, Mirandola SR, Al-Amoudi A, Mangan MS, Zimmer S, Monks BG, Fricke M, Schmidt RE, Espevik T, Jones B, Jarnicki AG, Hansbro PM, Busto P, Marshak-Rothstein A, Hornemann S, Aguzzi A, Kastenmüller W, Latz E. Franklin BS, et al. Among authors: zimmer s. Nat Immunol. 2014 Aug;15(8):727-37. doi: 10.1038/ni.2913. Epub 2014 Jun 22. Nat Immunol. 2014. PMID: 24952505 Free PMC article.
High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3.
De Nardo D, Labzin LI, Kono H, Seki R, Schmidt SV, Beyer M, Xu D, Zimmer S, Lahrmann C, Schildberg FA, Vogelhuber J, Kraut M, Ulas T, Kerksiek A, Krebs W, Bode N, Grebe A, Fitzgerald ML, Hernandez NJ, Williams BR, Knolle P, Kneilling M, Röcken M, Lütjohann D, Wright SD, Schultze JL, Latz E. De Nardo D, et al. Among authors: zimmer s. Nat Immunol. 2014 Feb;15(2):152-60. doi: 10.1038/ni.2784. Epub 2013 Dec 8. Nat Immunol. 2014. PMID: 24317040 Free PMC article.
Danger signaling in atherosclerosis.
Zimmer S, Grebe A, Latz E. Zimmer S, et al. Circ Res. 2015 Jan 16;116(2):323-40. doi: 10.1161/CIRCRESAHA.116.301135. Circ Res. 2015. PMID: 25593277 Review.
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming.
Zimmer S, Grebe A, Bakke SS, Bode N, Halvorsen B, Ulas T, Skjelland M, De Nardo D, Labzin LI, Kerksiek A, Hempel C, Heneka MT, Hawxhurst V, Fitzgerald ML, Trebicka J, Björkhem I, Gustafsson JÅ, Westerterp M, Tall AR, Wright SD, Espevik T, Schultze JL, Nickenig G, Lütjohann D, Latz E. Zimmer S, et al. Sci Transl Med. 2016 Apr 6;8(333):333ra50. doi: 10.1126/scitranslmed.aad6100. Sci Transl Med. 2016. PMID: 27053774 Free PMC article.
Statins improve NASH via inhibition of RhoA and Ras.
Schierwagen R, Maybüchen L, Hittatiya K, Klein S, Uschner FE, Braga TT, Franklin BS, Nickenig G, Strassburg CP, Plat J, Sauerbruch T, Latz E, Lütjohann D, Zimmer S, Trebicka J. Schierwagen R, et al. Among authors: zimmer s. Am J Physiol Gastrointest Liver Physiol. 2016 Oct 1;311(4):G724-G733. doi: 10.1152/ajpgi.00063.2016. Epub 2016 Sep 15. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 27634010 Free article.
Large extracellular vesicles in the left atrial appendage in patients with atrial fibrillation-the missing link?
Zietzer A, Al-Kassou B, Jamme P, Rolfes V, Steffen E, Bulic M, Hosen MR, Goody PR, Tiyerili V, Zimmer S, Schrickel JW, Sedaghat A, Franklin BS, Werner N, Nickenig G, Jansen F. Zietzer A, et al. Among authors: zimmer s. Clin Res Cardiol. 2022 Jan;111(1):34-49. doi: 10.1007/s00392-021-01873-4. Epub 2021 Jun 1. Clin Res Cardiol. 2022. PMID: 34061226 Free PMC article.
Cholesterol Crystal Dissolution Rate of Serum Predicts Outcomes in Patients With Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement.
Al-Kassou B, Al-Kassou L, Mahn T, Lütjohann D, Shamekhi J, Willemsen N, Niepmann ST, Baldus S, Kelm M, Nickenig G, Latz E, Zimmer S. Al-Kassou B, et al. Among authors: zimmer s. J Am Heart Assoc. 2024 Feb 6;13(3):e031997. doi: 10.1161/JAHA.123.031997. Epub 2024 Jan 19. J Am Heart Assoc. 2024. PMID: 38240198 Free article.
Circulating MicroRNA-122-5p Is Associated With a Lack of Improvement in Left Ventricular Function After Transcatheter Aortic Valve Replacement and Regulates Viability of Cardiomyocytes Through Extracellular Vesicles.
Hosen MR, Goody PR, Zietzer A, Xiang X, Niepmann ST, Sedaghat A, Tiyerili V, Chennupati R, Moore JB 4th, Boon RA, Uchida S, Sinning JM, Zimmer S, Latz E, Werner N, Nickenig G, Jansen F. Hosen MR, et al. Among authors: zimmer s. Circulation. 2022 Dec 13;146(24):1836-1854. doi: 10.1161/CIRCULATIONAHA.122.060258. Epub 2022 Jul 8. Circulation. 2022. PMID: 35862223 Free article.
633 results