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HDAC inhibition improves cardiopulmonary function in a feline model of diastolic dysfunction.
Wallner M, Eaton DM, Berretta RM, Liesinger L, Schittmayer M, Gindlhuber J, Wu J, Jeong MY, Lin YH, Borghetti G, Baker ST, Zhao H, Pfleger J, Blass S, Rainer PP, von Lewinski D, Bugger H, Mohsin S, Graier WF, Zirlik A, McKinsey TA, Birner-Gruenberger R, Wolfson MR, Houser SR. Wallner M, et al. Among authors: zirlik a. Sci Transl Med. 2020 Jan 8;12(525):eaay7205. doi: 10.1126/scitranslmed.aay7205. Sci Transl Med. 2020. PMID: 31915304 Free PMC article.
Impaired SIRT3 activity mediates cardiac dysfunction in endotoxemia by calpain-dependent disruption of ATP synthesis.
Koentges C, Cimolai MC, Pfeil K, Wolf D, Marchini T, Tarkhnishvili A, Hoffmann MM, Odening KE, Diehl P, von Zur Mühlen C, Alvarez S, Bode C, Zirlik A, Bugger H. Koentges C, et al. Among authors: zirlik a. J Mol Cell Cardiol. 2019 Aug;133:138-147. doi: 10.1016/j.yjmcc.2019.06.008. Epub 2019 Jun 13. J Mol Cell Cardiol. 2019. PMID: 31201798
Mitochondrial Mechanisms in Diabetic Cardiomyopathy.
Gollmer J, Zirlik A, Bugger H. Gollmer J, et al. Among authors: zirlik a. Diabetes Metab J. 2020 Feb;44(1):33-53. doi: 10.4093/dmj.2019.0185. Diabetes Metab J. 2020. PMID: 32097997 Free PMC article. Review.
Established and Emerging Mechanisms of Diabetic Cardiomyopathy.
Gollmer J, Zirlik A, Bugger H. Gollmer J, et al. Among authors: zirlik a. J Lipid Atheroscler. 2019 May;8(1):26-47. doi: 10.12997/jla.2019.8.1.26. Epub 2019 May 13. J Lipid Atheroscler. 2019. PMID: 32821697 Free PMC article. Review.
Nicotinamide for the treatment of heart failure with preserved ejection fraction.
Abdellatif M, Trummer-Herbst V, Koser F, Durand S, Adão R, Vasques-Nóvoa F, Freundt JK, Voglhuber J, Pricolo MR, Kasa M, Türk C, Aprahamian F, Herrero-Galán E, Hofer SJ, Pendl T, Rech L, Kargl J, Anto-Michel N, Ljubojevic-Holzer S, Schipke J, Brandenberger C, Auer M, Schreiber R, Koyani CN, Heinemann A, Zirlik A, Schmidt A, von Lewinski D, Scherr D, Rainer PP, von Maltzahn J, Mühlfeld C, Krüger M, Frank S, Madeo F, Eisenberg T, Prokesch A, Leite-Moreira AF, Lourenço AP, Alegre-Cebollada J, Kiechl S, Linke WA, Kroemer G, Sedej S. Abdellatif M, et al. Among authors: zirlik a. Sci Transl Med. 2021 Feb 10;13(580):eabd7064. doi: 10.1126/scitranslmed.abd7064. Sci Transl Med. 2021. PMID: 33568522 Free PMC article.
Loss of autophagy protein ATG5 impairs cardiac capacity in mice and humans through diminishing mitochondrial abundance and disrupting Ca2+ cycling.
Ljubojević-Holzer S, Kraler S, Djalinac N, Abdellatif M, Voglhuber J, Schipke J, Schmidt M, Kling KM, Franke GT, Herbst V, Zirlik A, von Lewinski D, Scherr D, Rainer PP, Kohlhaas M, Nickel A, Mühlfeld C, Maack C, Sedej S. Ljubojević-Holzer S, et al. Among authors: zirlik a. Cardiovasc Res. 2022 May 6;118(6):1492-1505. doi: 10.1093/cvr/cvab112. Cardiovasc Res. 2022. PMID: 33752242 Free PMC article.
193 results