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Renal hypertrophy is associated with upregulation of TGF-beta 1 gene expression in diabetic BB rat and NOD mouse.
Sharma K, Ziyadeh FN. Sharma K, et al. Among authors: ziyadeh fn. Am J Physiol. 1994 Dec;267(6 Pt 2):F1094-01. doi: 10.1152/ajprenal.1994.267.6.F1094. Am J Physiol. 1994. PMID: 7810696
ANG II is a mitogen for a murine cell line isolated from medullary thick ascending limb of Henle's loop.
Wolf G, Ziyadeh FN, Helmchen U, Zahner G, Schroeder R, Stahl RA. Wolf G, et al. Among authors: ziyadeh fn. Am J Physiol. 1995 May;268(5 Pt 2):F940-7. doi: 10.1152/ajprenal.1995.268.5.F940. Am J Physiol. 1995. PMID: 7771522
Inhibiting albumin glycation ameliorates diabetic nephropathy in the db/db mouse.
Cohen MP, Masson N, Hud E, Ziyadeh F, Han DC, Clements RS. Cohen MP, et al. Exp Nephrol. 2000 May-Jun;8(3):135-43. doi: 10.1159/000020661. Exp Nephrol. 2000. PMID: 10810230
Assessment of 115 candidate genes for diabetic nephropathy by transmission/disequilibrium test.
Ewens KG, George RA, Sharma K, Ziyadeh FN, Spielman RS. Ewens KG, et al. Among authors: ziyadeh fn. Diabetes. 2005 Nov;54(11):3305-18. doi: 10.2337/diabetes.54.11.3305. Diabetes. 2005. PMID: 16249459
From the periphery of the glomerular capillary wall toward the center of disease: podocyte injury comes of age in diabetic nephropathy.
Wolf G, Chen S, Ziyadeh FN. Wolf G, et al. Among authors: ziyadeh fn. Diabetes. 2005 Jun;54(6):1626-34. doi: 10.2337/diabetes.54.6.1626. Diabetes. 2005. PMID: 15919782 Review.
Angiotensin II stimulates alpha3(IV) collagen production in mouse podocytes via TGF-beta and VEGF signalling: implications for diabetic glomerulopathy.
Chen S, Lee JS, Iglesias-de la Cruz MC, Wang A, Izquierdo-Lahuerta A, Gandhi NK, Danesh FR, Wolf G, Ziyadeh FN. Chen S, et al. Among authors: ziyadeh fn. Nephrol Dial Transplant. 2005 Jul;20(7):1320-8. doi: 10.1093/ndt/gfh837. Epub 2005 Apr 19. Nephrol Dial Transplant. 2005. PMID: 15840669
Podocyte-derived vascular endothelial growth factor mediates the stimulation of alpha3(IV) collagen production by transforming growth factor-beta1 in mouse podocytes.
Chen S, Kasama Y, Lee JS, Jim B, Marin M, Ziyadeh FN. Chen S, et al. Among authors: ziyadeh fn. Diabetes. 2004 Nov;53(11):2939-49. doi: 10.2337/diabetes.53.11.2939. Diabetes. 2004. PMID: 15504975
Mediators of diabetic renal disease: the case for tgf-Beta as the major mediator.
Ziyadeh FN. Ziyadeh FN. J Am Soc Nephrol. 2004 Jan;15 Suppl 1:S55-7. doi: 10.1097/01.asn.0000093460.24823.5b. J Am Soc Nephrol. 2004. PMID: 14684674 Review.
Regulation of inducible class II MHC, costimulatory molecules, and cytokine expression in TGF-beta1 knockout renal epithelial cells: effect of exogenous TGF-beta1.
Banu N, Mozes MM, Kopp JB, Ziyadeh FN, Meyers CM. Banu N, et al. Among authors: ziyadeh fn. Exp Nephrol. 2002;10(5-6):320-31. doi: 10.1159/000065295. Exp Nephrol. 2002. PMID: 12381916
Reversibility of established diabetic glomerulopathy by anti-TGF-beta antibodies in db/db mice.
Chen S, Iglesias-de la Cruz MC, Jim B, Hong SW, Isono M, Ziyadeh FN. Chen S, et al. Among authors: ziyadeh fn. Biochem Biophys Res Commun. 2003 Jan 3;300(1):16-22. doi: 10.1016/s0006-291x(02)02708-0. Biochem Biophys Res Commun. 2003. PMID: 12480514
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