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Disposition of metformin: variability due to polymorphisms of organic cation transporters.
Zolk O. Zolk O. Ann Med. 2012 Mar;44(2):119-29. doi: 10.3109/07853890.2010.549144. Epub 2011 Mar 3. Ann Med. 2012. PMID: 21366511 Review.
ATP-binding cassette transporters in the heart.
Solbach TF, König J, Fromm MF, Zolk O. Solbach TF, et al. Among authors: zolk o. Trends Cardiovasc Med. 2006 Jan;16(1):7-15. doi: 10.1016/j.tcm.2005.10.001. Trends Cardiovasc Med. 2006. PMID: 16387624 Review.
MDR1 genotype-dependent regulation of the aldosterone system in humans.
Zolk O, Jacobi J, Pahl A, Fromm MF, Schmieder RE. Zolk O, et al. Pharmacogenet Genomics. 2007 Feb;17(2):137-44. doi: 10.1097/01.fpc.0000239969.46594.d0. Pharmacogenet Genomics. 2007. PMID: 17301693 Clinical Trial.
ATP-binding cassette transporters in human heart failure.
Solbach TF, Paulus B, Weyand M, Eschenhagen T, Zolk O, Fromm MF. Solbach TF, et al. Among authors: zolk o. Naunyn Schmiedebergs Arch Pharmacol. 2008 May;377(3):231-43. doi: 10.1007/s00210-008-0279-6. Epub 2008 Apr 8. Naunyn Schmiedebergs Arch Pharmacol. 2008. PMID: 18392808
Structural determinants of inhibitor interaction with the human organic cation transporter OCT2 (SLC22A2).
Zolk O, Solbach TF, König J, Fromm MF. Zolk O, et al. Naunyn Schmiedebergs Arch Pharmacol. 2009 Apr;379(4):337-48. doi: 10.1007/s00210-008-0369-5. Epub 2008 Nov 11. Naunyn Schmiedebergs Arch Pharmacol. 2009. PMID: 19002438
Functional characterization of the human organic cation transporter 2 variant p.270Ala>Ser.
Zolk O, Solbach TF, König J, Fromm MF. Zolk O, et al. Drug Metab Dispos. 2009 Jun;37(6):1312-8. doi: 10.1124/dmd.108.023762. Epub 2009 Feb 27. Drug Metab Dispos. 2009. PMID: 19251820
Current understanding of the pharmacogenomics of metformin.
Zolk O. Zolk O. Clin Pharmacol Ther. 2009 Dec;86(6):595-8. doi: 10.1038/clpt.2009.144. Clin Pharmacol Ther. 2009. PMID: 19915604
Gender is an important determinant of the disposition of the loop diuretic torasemide.
Werner U, Werner D, Heinbüchner S, Graf B, Ince H, Kische S, Thürmann P, König J, Fromm MF, Zolk O. Werner U, et al. Among authors: zolk o. J Clin Pharmacol. 2010 Feb;50(2):160-8. doi: 10.1177/0091270009337514. Epub 2009 Nov 23. J Clin Pharmacol. 2010. PMID: 19934028 Clinical Trial.
The prostaglandin transporter OATP2A1 is expressed in human ocular tissues and transports the antiglaucoma prostanoid latanoprost.
Kraft ME, Glaeser H, Mandery K, König J, Auge D, Fromm MF, Schlötzer-Schrehardt U, Welge-Lüssen U, Kruse FE, Zolk O. Kraft ME, et al. Among authors: zolk o. Invest Ophthalmol Vis Sci. 2010 May;51(5):2504-11. doi: 10.1167/iovs.09-4290. Epub 2009 Dec 17. Invest Ophthalmol Vis Sci. 2010. PMID: 20019365
Drug transport by breast cancer resistance protein.
Poguntke M, Hazai E, Fromm MF, Zolk O. Poguntke M, et al. Among authors: zolk o. Expert Opin Drug Metab Toxicol. 2010 Nov;6(11):1363-84. doi: 10.1517/17425255.2010.519700. Epub 2010 Sep 27. Expert Opin Drug Metab Toxicol. 2010. PMID: 20873966
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