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Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.
Jørgensen H, Degnes KF, Sletta H, Fjaervik E, Dikiy A, Herfindal L, Bruheim P, Klinkenberg G, Bredholt H, Nygård G, Døskeland SO, Ellingsen TE, Zotchev SB. Jørgensen H, et al. Among authors: zotchev sb. Chem Biol. 2009 Oct 30;16(10):1109-21. doi: 10.1016/j.chembiol.2009.09.014. Chem Biol. 2009. PMID: 19875084
87 results