Zou L - Search Results

1

Interactions of Oral Molecular Excipients with Breast Cancer Resistance Protein, BCRP.

Zou L, Pottel J, Khuri N, Ngo HX, Ni Z, Tsakalozou E, Warren MS, Huang Y, Shoichet BK, Giacomini KM. Zou L, et al. Mol Pharm. 2020 Mar 2;17(3):748-756. doi: 10.1021/acs.molpharmaceut.9b00658. Epub 2020 Feb 10. Mol Pharm. 2020. PMID: 31990564 Free PMC article.

2

Impact of Pharmaceutical Excipients on Oral Drug Absorption: A Focus on Intestinal Drug Transporters.

Zou L, Ni Z, Tsakalozou E, Giacomini KM. Zou L, et al. Clin Pharmacol Ther. 2019 Feb;105(2):323-325. doi: 10.1002/cpt.1292. Epub 2019 Jan 20. Clin Pharmacol Ther. 2019. PMID: 30663035 No abstract available.

3

Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives.

Zou L, Spanogiannopoulos P, Pieper LM, Chien HC, Cai W, Khuri N, Pottel J, Vora B, Ni Z, Tsakalozou E, Zhang W, Shoichet BK, Giacomini KM, Turnbaugh PJ. Zou L, et al. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):16009-16018. doi: 10.1073/pnas.1920483117. Epub 2020 Jun 22. Proc Natl Acad Sci U S A. 2020. PMID: 32571913 Free PMC article.

4

Interaction of Commonly Used Oral Molecular Excipients with P-glycoprotein.

Bajaj R, Chong LB, Zou L, Tsakalozou E, Ni Z, Giacomini KM, Kroetz DL. Bajaj R, et al. Among authors: zou l. AAPS J. 2021 Sep 15;23(5):106. doi: 10.1208/s12248-021-00631-8. AAPS J. 2021. PMID: 34528148 Free PMC article.

5

A Molecular Basis for Innovation in Drug Excipients.

Irwin JJ, Pottel J, Zou L, Wen H, Zuk S, Zhang X, Sterling T, Shoichet BK, Lionberger R, Giacomini KM. Irwin JJ, et al. Among authors: zou l. Clin Pharmacol Ther. 2017 Mar;101(3):320-323. doi: 10.1002/cpt.458. Epub 2016 Sep 28. Clin Pharmacol Ther. 2017. PMID: 27557422 Review.

6

The activities of drug inactive ingredients on biological targets.

Pottel J, Armstrong D, Zou L, Fekete A, Huang XP, Torosyan H, Bednarczyk D, Whitebread S, Bhhatarai B, Liang G, Jin H, Ghaemi SN, Slocum S, Lukacs KV, Irwin JJ, Berg EL, Giacomini KM, Roth BL, Shoichet BK, Urban L. Pottel J, et al. Among authors: zou l. Science. 2020 Jul 24;369(6502):403-413. doi: 10.1126/science.aaz9906. Science. 2020. PMID: 32703874 Free PMC article.

7

Drug Metabolites Potently Inhibit Renal Organic Anion Transporters, OAT1 and OAT3.

Zou L, Matsson P, Stecula A, Ngo HX, Zur AA, Giacomini KM. Zou L, et al. J Pharm Sci. 2021 Jan;110(1):347-353. doi: 10.1016/j.xphs.2020.09.004. Epub 2020 Sep 7. J Pharm Sci. 2021. PMID: 32910949 Free PMC article.

8

Deorphaning a solute carrier 22 family member, SLC22A15, through functional genomic studies.

Yee SW, Buitrago D, Stecula A, Ngo HX, Chien HC, Zou L, Koleske ML, Giacomini KM. Yee SW, et al. Among authors: zou l. FASEB J. 2020 Dec;34(12):15734-15752. doi: 10.1096/fj.202001497R. Epub 2020 Oct 30. FASEB J. 2020. PMID: 33124720 Free PMC article.

9

Oxypurinol pharmacokinetics and pharmacodynamics in healthy volunteers: Influence of BCRP Q141K polymorphism and patient characteristics.

Vora B, Brackman DJ, Zou L, Garcia-Cremades M, Sirota M, Savic RM, Giacomini KM. Vora B, et al. Among authors: zou l. Clin Transl Sci. 2021 Jul;14(4):1431-1443. doi: 10.1111/cts.12992. Epub 2021 May 1. Clin Transl Sci. 2021. PMID: 33931953 Free PMC article. Clinical Trial.

10

Drugs in COVID-19 Clinical Trials: Predicting Transporter-Mediated Drug-Drug Interactions Using In Vitro Assays and Real-World Data.

Yee SW, Vora B, Oskotsky T, Zou L, Jakobsen S, Enogieru OJ, Koleske ML, Kosti I, Rödin M, Sirota M, Giacomini KM. Yee SW, et al. Among authors: zou l. Clin Pharmacol Ther. 2021 Jul;110(1):108-122. doi: 10.1002/cpt.2236. Epub 2021 May 3. Clin Pharmacol Ther. 2021. PMID: 33759449 Free PMC article.

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