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PPARdelta regulates multiple proinflammatory pathways to suppress atherosclerosis.
Barish GD, Atkins AR, Downes M, Olson P, Chong LW, Nelson M, Zou Y, Hwang H, Kang H, Curtiss L, Evans RM, Lee CH. Barish GD, et al. Among authors: zou y. Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4271-6. doi: 10.1073/pnas.0711875105. Epub 2008 Mar 12. Proc Natl Acad Sci U S A. 2008. PMID: 18337509 Free PMC article.
AMPK and PPARdelta agonists are exercise mimetics.
Narkar VA, Downes M, Yu RT, Embler E, Wang YX, Banayo E, Mihaylova MM, Nelson MC, Zou Y, Juguilon H, Kang H, Shaw RJ, Evans RM. Narkar VA, et al. Among authors: zou y. Cell. 2008 Aug 8;134(3):405-15. doi: 10.1016/j.cell.2008.06.051. Epub 2008 Jul 31. Cell. 2008. PMID: 18674809 Free PMC article.
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