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Systematic review: T-cell-based assays for the diagnosis of latent tuberculosis infection: an update.
Pai M, Zwerling A, Menzies D. Pai M, et al. Ann Intern Med. 2008 Aug 5;149(3):177-84. doi: 10.7326/0003-4819-149-3-200808050-00241. Epub 2008 Jun 30. Ann Intern Med. 2008. PMID: 18593687 Free PMC article. Review.
A recent meta-analysis showed that IGRAs have high specificity, even among populations that have received bacille Calmette-Guérin (BCG) vaccination. ...DATA SYNTHESIS: A fixed-effects meta-analysis with correction for overdispersion was done to pool data within pres
A recent meta-analysis showed that IGRAs have high specificity, even among populations that have received bacille Calmette-Guérin (BC
Use of geographic and genotyping tools to characterise tuberculosis transmission in Montreal.
Haase I, Olson S, Behr MA, Wanyeki I, Thibert L, Scott A, Zwerling A, Ross N, Brassard P, Menzies D, Schwartzman K. Haase I, et al. Int J Tuberc Lung Dis. 2007 Jun;11(6):632-8. Int J Tuberc Lung Dis. 2007. PMID: 17519094
After a hot spot analysis suggested two areas of overconcentration, we conducted a spatial scan, with census tracts (population 2500-8000) as the primary unit of analysis and stratification by birthplace. ...CONCLUSIONS: In a city with low overall incidence, …
After a hot spot analysis suggested two areas of overconcentration, we conducted a spatial scan, with census tracts (populatio …
GenoType MTBDR assays for the diagnosis of multidrug-resistant tuberculosis: a meta-analysis.
Ling DI, Zwerling AA, Pai M. Ling DI, et al. Eur Respir J. 2008 Nov;32(5):1165-74. doi: 10.1183/09031936.00061808. Epub 2008 Jul 9. Eur Respir J. 2008. PMID: 18614561
The present authors carried out a systematic review and used meta-analysis methods appropriate for diagnostic accuracy. After the literature searches, 14 comparisons for rifampicin and 15 comparisons for isoniazid were identified in 10 articles that used GenoType MTBDR ass …
The present authors carried out a systematic review and used meta-analysis methods appropriate for diagnostic accuracy. After the lit …
T-cell assay conversions and reversions among household contacts of tuberculosis patients in rural India.
Pai M, Joshi R, Dogra S, Zwerling AA, Gajalakshmi D, Goswami K, Reddy MV, Kalantri A, Hill PC, Menzies D, Hopewell PC. Pai M, et al. Int J Tuberc Lung Dis. 2009 Jan;13(1):84-92. Int J Tuberc Lung Dis. 2009. PMID: 19105884 Free PMC article.
In a pilot study, we determined conversions and reversions using QuantiFERON-TB Gold In-Tube((R)) (QFT) among household contacts of TB cases, and evaluated the effect of using various definitions and criteria for conversions. DESIGN: In a cohort of 250 contacts in I …
In a pilot study, we determined conversions and reversions using QuantiFERON-TB Gold In-Tube((R)) (QFT) among household contacts of T …
Major Mycobacterium tuberculosis lineages associate with patient country of origin.
Reed MB, Pichler VK, McIntosh F, Mattia A, Fallow A, Masala S, Domenech P, Zwerling A, Thibert L, Menzies D, Schwartzman K, Behr MA. Reed MB, et al. J Clin Microbiol. 2009 Apr;47(4):1119-28. doi: 10.1128/JCM.02142-08. Epub 2009 Feb 11. J Clin Microbiol. 2009. PMID: 19213699 Free PMC article.
Presently, the most effective means of assigning isolates into a series of unambiguous lineages is the method of Gagneux et al. ...In this manner, isolates are classified into six major lineages, the majority of which display a high degree of geographic restriction. …
Presently, the most effective means of assigning isolates into a series of unambiguous lineages is the method of Gagneux et al. ...In …
Tuberculosis and the city.
Carter A, Zwerling A, Olson S, Tannenbaum TN, Schwartzman K. Carter A, et al. Health Place. 2009 Sep;15(3):777-83. doi: 10.1016/j.healthplace.2009.01.002. Epub 2009 Jan 29. Health Place. 2009. PMID: 19233710
Novel and improved technologies for tuberculosis diagnosis: progress and challenges.
Pai M, Minion J, Sohn H, Zwerling A, Perkins MD. Pai M, et al. Clin Chest Med. 2009 Dec;30(4):701-16, viii. doi: 10.1016/j.ccm.2009.08.016. Clin Chest Med. 2009. PMID: 19925962 Review.
Despite a decade of success in improving cure rates for tuberculosis (TB), diagnosis and case detection remain a major obstacle to TB control. This article reviews the existing evidence base on TB diagnostics, describes the progress of new technologies, and ends wit …
Despite a decade of success in improving cure rates for tuberculosis (TB), diagnosis and case detection remain a major obstacl …
Within-subject variability of interferon-g assay results for tuberculosis and boosting effect of tuberculin skin testing: a systematic review.
van Zyl-Smit RN, Zwerling A, Dheda K, Pai M. van Zyl-Smit RN, et al. PLoS One. 2009 Dec 30;4(12):e8517. doi: 10.1371/journal.pone.0008517. PLoS One. 2009. PMID: 20041113 Free PMC article. Review.
However, the effect of a preceding TST on subsequent IGRA results has been reported in studies with apparently conflicting results. ...A TST induced "boosting" of IGRA responses was demonstrated in several studies and although more pronounced in IGRA-positive (i.e. …
However, the effect of a preceding TST on subsequent IGRA results has been reported in studies with apparently conflicting results. . …
Rapid diagnosis of drug-resistant TB using line probe assays: from evidence to policy.
Ling DI, Zwerling AA, Pai M. Ling DI, et al. Expert Rev Respir Med. 2008 Oct;2(5):583-8. doi: 10.1586/17476348.2.5.583. Expert Rev Respir Med. 2008. PMID: 20477293
Evidence from a systematic review suggests that INNO-LiPA is a highly sensitive and specific test for the detection of rifampicin resistance in culture isolates. ...Whether molecular tools, such as line probe assays, will actually make a clinical and public-h …
Evidence from a systematic review suggests that INNO-LiPA is a highly sensitive and specific test for the detection of rifampi …
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