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HTS-compatible FRET-based conformational sensors clarify membrane receptor activation.
Scholler P, Moreno-Delgado D, Lecat-Guillet N, Doumazane E, Monnier C, Charrier-Savournin F, Fabre L, Chouvet C, Soldevila S, Lamarque L, Donsimoni G, Roux T, Zwier JM, Trinquet E, Rondard P, Pin JP. Scholler P, et al. Among authors: zwier jm. Nat Chem Biol. 2017 Apr;13(4):372-380. doi: 10.1038/nchembio.2286. Epub 2017 Jan 30. Nat Chem Biol. 2017. PMID: 28135236
Time-resolved FRET strategy to screen GPCR ligand library.
Oueslati N, Hounsou C, Belhocine A, Rodriguez T, Dupuis E, Zwier JM, Trinquet E, Pin JP, Durroux T. Oueslati N, et al. Among authors: zwier jm. Methods Mol Biol. 2015;1272:23-36. doi: 10.1007/978-1-4939-2336-6_2. Methods Mol Biol. 2015. PMID: 25563174
Structural insights into biased G protein-coupled receptor signaling revealed by fluorescence spectroscopy.
Rahmeh R, Damian M, Cottet M, Orcel H, Mendre C, Durroux T, Sharma KS, Durand G, Pucci B, Trinquet E, Zwier JM, Deupi X, Bron P, Banères JL, Mouillac B, Granier S. Rahmeh R, et al. Among authors: zwier jm. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6733-8. doi: 10.1073/pnas.1201093109. Epub 2012 Apr 9. Proc Natl Acad Sci U S A. 2012. PMID: 22493271 Free PMC article.
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