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Acemannan, an extracted polysaccharide from Aloe vera: A literature review.
Sierra-García GD, Castro-Ríos R, González-Horta A, Lara-Arias J, Chávez-Montes A. Sierra-García GD, et al. Nat Prod Commun. 2014 Aug;9(8):1217-21. Nat Prod Commun. 2014. PMID: 25233608 Review.
Acemannan has various medicinal properties like osteogenic, anti-inflammatory, and antibacterial, which accelerate healing of lesions. Also, acemannan is known to have antiviral and antitumor activities in vivo through activation of immune responses. ...
Acemannan has various medicinal properties like osteogenic, anti-inflammatory, and antibacterial, which accelerate healing of lesions …
Pharmacodynamics of Aloe vera and acemannan in therapeutic applications for skin, digestion, and immunomodulation.
Sadgrove NJ, Simmonds MSJ. Sadgrove NJ, et al. Phytother Res. 2021 Dec;35(12):6572-6584. doi: 10.1002/ptr.7242. Epub 2021 Aug 24. Phytother Res. 2021. PMID: 34427371 Review.
Furthermore, in vitro outcomes demonstrate that the breakage of acemannan chains into smaller fragments enhances biological effects. These fragments can intravenously boost vaccine efficacy or entrain the immune system to attack cancer cells by mannose receptor agon …
Furthermore, in vitro outcomes demonstrate that the breakage of acemannan chains into smaller fragments enhances biological effects. …
The impact of acemannan on the generation and function of cytotoxic T-lymphocytes.
Womble D, Helderman JH. Womble D, et al. Immunopharmacol Immunotoxicol. 1992;14(1-2):63-77. doi: 10.3109/08923979209009213. Immunopharmacol Immunotoxicol. 1992. PMID: 1597661
Acemannan, an antiviral agent with immune enhancement capabilities, was studied for its impact on cytotoxic T-lymphocyte (Tc) function generated in response to alloantigen. ...No dose of acemannan was found to be cytotoxic to these cells. In conclusion, ac …
Acemannan, an antiviral agent with immune enhancement capabilities, was studied for its impact on cytotoxic T-lymphocyte (Tc) …
Acemannan coated, cobalt-doped biphasic calcium phosphate nanoparticles for immunomodulation regulated bone regeneration.
Negi D, Bhavya K, Pal D, Singh Y. Negi D, et al. Biomater Sci. 2024 Jul 9;12(14):3672-3685. doi: 10.1039/d4bm00482e. Biomater Sci. 2024. PMID: 38864476
Biomaterials are used as scaffolds in bone regeneration to facilitate the restoration of bone tissues. The local immune microenvironment affects bone repair but the role of immune response in biomaterial-facilitated osteogenesis has been largely overlooked and it pr …
Biomaterials are used as scaffolds in bone regeneration to facilitate the restoration of bone tissues. The local immune microenvironm …
Role of acemannan O-acetyl group in murine radioprotection.
Kumar S, Kumar R. Kumar S, et al. Carbohydr Polym. 2019 Mar 1;207:460-470. doi: 10.1016/j.carbpol.2018.12.003. Epub 2018 Dec 6. Carbohydr Polym. 2019. PMID: 30600029
Acetylation enhances acemannan viscosity and thermal stability. Free radicals scavenging and Fenton reaction inhibition was mediated by acemannan acetyl and hydroxyl group respectively. ...Over-acetylated acemannan has stronger effects on immunomodulation/rad …
Acetylation enhances acemannan viscosity and thermal stability. Free radicals scavenging and Fenton reaction inhibition was mediated …
A New Biomaterial Derived from Aloe vera-Acemannan from Basic Studies to Clinical Application.
Bai Y, Niu Y, Qin S, Ma G. Bai Y, et al. Pharmaceutics. 2023 Jul 9;15(7):1913. doi: 10.3390/pharmaceutics15071913. Pharmaceutics. 2023. PMID: 37514099 Free PMC article. Review.
Aloe vera is a kind of herb rich in polysaccharides. Acemannan (AC) is considered to be a natural polysaccharide with good biodegradability and biocompatibility extracted from Aloe vera and has a wide range of applications in the biomedical field due to excellent immunomod …
Aloe vera is a kind of herb rich in polysaccharides. Acemannan (AC) is considered to be a natural polysaccharide with good biodegrada …
Enhancement of allo-responsiveness of human lymphocytes by acemannan (Carrisyn).
Womble D, Helderman JH. Womble D, et al. Int J Immunopharmacol. 1988;10(8):967-74. doi: 10.1016/0192-0561(88)90043-4. Int J Immunopharmacol. 1988. PMID: 2975271
The recent isolation of the active ingredient, acemannan, has made testing of this drug important. Since the drug appears to enhance monocyte function in other experiments, these studies were designed to test the capacity of acemannan to enhance immune respon …
The recent isolation of the active ingredient, acemannan, has made testing of this drug important. Since the drug appears to enhance …
The Effect of Aloe vera on Skin and Its Commensals: Contribution of Acemannan in Curing Acne Caused by Propionibacterium acnes.
Pal S, Raj M, Singh M, Saurav K, Paliwal C, Saha S, Sharma AK, Singh M. Pal S, et al. Microorganisms. 2024 Oct 16;12(10):2070. doi: 10.3390/microorganisms12102070. Microorganisms. 2024. PMID: 39458379 Free PMC article. Review.
Commensals present on the skin have a crucial role in training the human immune system against other pathogenic microbes. Propionibacterium acnes act as an opportunistic pathogen when the balance between the commensals is disturbed. ...The hyperproliferation of Propionibac …
Commensals present on the skin have a crucial role in training the human immune system against other pathogenic microbes. Propionibac …
Acemannan purified from Aloe vera induces phenotypic and functional maturation of immature dendritic cells.
Lee JK, Lee MK, Yun YP, Kim Y, Kim JS, Kim YS, Kim K, Han SS, Lee CK. Lee JK, et al. Int Immunopharmacol. 2001 Jul;1(7):1275-84. doi: 10.1016/s1567-5769(01)00052-2. Int Immunopharmacol. 2001. PMID: 11460308
Acemannan, a major carbohydrate fraction of Aloe vera gel, has been known to have antiviral and antitumoral activities in vivo through activation of immune responses. The present study was set out to define the immunomodulatory activity of acemannan on dendri …
Acemannan, a major carbohydrate fraction of Aloe vera gel, has been known to have antiviral and antitumoral activities in vivo throug …
Upregulation of phagocytosis and candidicidal activity of macrophages exposed to the immunostimulant acemannan.
Stuart RW, Lefkowitz DL, Lincoln JA, Howard K, Gelderman MP, Lefkowitz SS. Stuart RW, et al. Int J Immunopharmacol. 1997 Feb;19(2):75-82. doi: 10.1016/s0192-0561(97)00010-6. Int J Immunopharmacol. 1997. PMID: 9278177
The present study was done to determine if the immunostimulant, acemannan prepared from aloe vera, could stimulate MO in a similar manner. Resident peritoneal MO collected from C57BL/6 mice were exposed to acemannan for 10 min. ...If MO were incubated with aceman …
The present study was done to determine if the immunostimulant, acemannan prepared from aloe vera, could stimulate MO in a similar ma …
23 results