Enhanced delivery of hydrophilic peptides in vitro by transdermal microneedle pretreatment.
Zhang S, Qiu Y, Gao Y.
Zhang S, et al.
Acta Pharm Sin B. 2014 Feb;4(1):100-4. doi: 10.1016/j.apsb.2013.12.011. Epub 2014 Jan 24.
Acta Pharm Sin B. 2014.
PMID: 26579370
Free PMC article.
Four model peptides were used (Gly-Gln-Pro-Arg [tetrapeptide-3, 456.6 Da], Val-Gly-Val-Ala-Pro-Gly [hexapeptide, 498.6 Da], AC-Glu-Glu-Met-Gln-Arg-Arg-NH2 [acetyl hexapeptide-3, 889 Da] and Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 [oxytocin, 1007.2 Da]). ...A …
Four model peptides were used (Gly-Gln-Pro-Arg [tetrapeptide-3, 456.6 Da], Val-Gly-Val-Ala-Pro-Gly [hexapeptide, 498.6 Da], AC-Glu-Glu-Met-G …