Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 1
2007 1
2009 1
2010 1
2011 1
2012 1
2013 1
2016 2
2018 1
2019 1
2020 4
2022 5
2024 3
2025 5
2026 2

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

28 results

Results by year

Filters applied: . Clear all
Page 1
Bioactive potential of Centella asiatica leaf extract in acetylcholinesterase (AChE) inhibition: Insights from multiple ligand mapping.
Khairinisa MA, Fakih TM, Ramadhan DSF. Khairinisa MA, et al. Comput Biol Med. 2025 Oct;197(Pt A):110970. doi: 10.1016/j.compbiomed.2025.110970. Epub 2025 Aug 26. Comput Biol Med. 2025. PMID: 40865263
Centella asiatica, commonly known as Gotu Kola, has been used for centuries in traditional medicine due to its neuroprotective and cognitive-enhancing properties. This study explores the potential of bioactive compounds from Centella asiatica, including asiaticoside …
Centella asiatica, commonly known as Gotu Kola, has been used for centuries in traditional medicine due to its neuroprotective and co …
Inhibitory Effects of Raw-Extract Centella asiatica (RECA) on Acetylcholinesterase, Inflammations, and Oxidative Stress Activities via In Vitro and In Vivo.
Hafiz ZZ, Amin M'M, Johari James RM, Teh LK, Salleh MZ, Adenan MI. Hafiz ZZ, et al. Molecules. 2020 Feb 17;25(4):892. doi: 10.3390/molecules25040892. Molecules. 2020. PMID: 32079355 Free PMC article.
Centella asiatica (C. asiatica) is one of the medicinal plants that has been reported to exert comprehensive neuroprotection in vitro and in vivo. In view of this, the present study was performed to investigate the effect of ethanolic extract of C. asiatica, designated as …
Centella asiatica (C. asiatica) is one of the medicinal plants that has been reported to exert comprehensive neuroprotection in vitro …
Centella asiatica ameliorates scopolamine-induced cognitive impairment via acetylcholinesterase modulation and oxidative stress reduction.
Kim YJ, Kang YM, Pak ME, Eom HJ, Kim KY, Hur N, Seo Y, Oh TK, Bae J, Lee JK, Kim K. Kim YJ, et al. Food Sci Biotechnol. 2026 Mar 25;35(6):1611-1623. doi: 10.1007/s10068-026-02132-w. eCollection 2026 May. Food Sci Biotechnol. 2026. PMID: 42077787 Free PMC article.
Centella asiatica, a traditional medicinal herb, is well-known for its neuroprotective, antioxidant, and anti-inflammatory effects. ...Furthermore, CAE elevated hippocampal acetylcholine levels, inhibited acetylcholinesterase activity, and enhanced antioxidant defen …
Centella asiatica, a traditional medicinal herb, is well-known for its neuroprotective, antioxidant, and anti-inflammatory effects. . …
Centella asiatica prevents D-galactose-Induced cognitive deficits, oxidative stress and neurodegeneration in the adult rat brain.
Firdaus Z, Singh N, Prajapati SK, Krishnamurthy S, Singh TD. Firdaus Z, et al. Drug Chem Toxicol. 2022 May;45(3):1417-1426. doi: 10.1080/01480545.2020.1833907. Epub 2020 Oct 20. Drug Chem Toxicol. 2022. PMID: 33078641
Chronic D-galactose (D-gal) administration causes cognitive impairment and is used widely in animal models for anti-aging studies. Centella asiatica (CA), a traditional herbal medicine, has been used as a brain tonic to enhance memory. This study evaluates the neuroprotect …
Chronic D-galactose (D-gal) administration causes cognitive impairment and is used widely in animal models for anti-aging studies. Centel …
Combining In Silico and In Vitro Studies to Evaluate the Acetylcholinesterase Inhibitory Profile of Different Accessions and the Biomarker Triterpenes of Centella asiatica.
Jusril NA, Muhamad Juhari ANN, Abu Bakar SI, Md Saad WM, Adenan MI. Jusril NA, et al. Molecules. 2020 Jul 24;25(15):3353. doi: 10.3390/molecules25153353. Molecules. 2020. PMID: 32721993 Free PMC article.
Alzheimer's disease (AD) is a neurodegenerative disease and the most cause of dementia in elderly adults. Acetylcholinesterase (AChE) is an important beneficial target for AD to control cholinergic signaling deficit. Centella asiatica (CA) has proven to be rich with …
Alzheimer's disease (AD) is a neurodegenerative disease and the most cause of dementia in elderly adults. Acetylcholinesterase (AChE) …
Protective Effects of Centella asiatica on Cognitive Deficits Induced by D-gal/AlCl3 via Inhibition of Oxidative Stress and Attenuation of Acetylcholinesterase Level.
Chiroma SM, Baharuldin MTH, Mat Taib CN, Amom Z, Jagadeesan S, Ilham Adenan M, Mahdi O, Moklas MAM. Chiroma SM, et al. Toxics. 2019 Mar 30;7(2):19. doi: 10.3390/toxics7020019. Toxics. 2019. PMID: 30935005 Free PMC article.
Alzheimer's disease (AD) is a progressive neurodegenerative disorder with cholinergic dysfunctions and impaired redox homeostasis. The plant Centella asiatica (CA) is renowned for its nutritional benefits and herbal formulas for promoting health, enhancing cognition, and i …
Alzheimer's disease (AD) is a progressive neurodegenerative disorder with cholinergic dysfunctions and impaired redox homeostasis. The plant …
Nanoemulsion of Ethanolic Extract of Centella asiatica (NanoSECA)Ameliorates Learning and Memory Performance by EnhancingCholinergic Activities, Increasing Antioxidative Levels, and AttenuatingOxidative Stress Markers in Adult Rats.
Jusril NA, Mukhtar SM, Abu Bakar SI, Md Saad WM, Wen NK, Adenan MI. Jusril NA, et al. Pharm Nanotechnol. 2024;12(4):329-339. doi: 10.2174/2211738511666230831122844. Pharm Nanotechnol. 2024. PMID: 37653639
BACKGROUND: Centella asiatica (C. asiatica) has long been traditionally used as a memory enhancer. Nanoemulsion of ethanolic extract C. asiatica (NanoSECA) has been developed to improve brain functions. ...Different brain sections were isolated, homogenized, and tested for …
BACKGROUND: Centella asiatica (C. asiatica) has long been traditionally used as a memory enhancer. Nanoemulsion of ethanolic extract …
Computer-aided discovery of dual-target compounds for Alzheimer's from ayurvedic medicinal plants.
Shah M, Pervaiz S, Ahmad I, Ansari SH, Junior VFP, Ahmed S, Khan MU, Fawy KF, Nishan U, Dib H, Abdelfattah MAO. Shah M, et al. PLoS One. 2025 Jun 25;20(6):e0325441. doi: 10.1371/journal.pone.0325441. eCollection 2025. PLoS One. 2025. PMID: 40560959 Free PMC article.
It involves the dysfunction of key enzymes such as Acetylcholinesterase (AChE) and beta-secretase (BACE1), making them critical targets for therapeutic intervention. ...Virtual screening resulted in 15 ligands, mostly belonging to the ursane-type or dammarene-type triterpe …
It involves the dysfunction of key enzymes such as Acetylcholinesterase (AChE) and beta-secretase (BACE1), making them critical targe …
Centella asiatica Alleviates AlCl(3)-induced Cognitive Impairment, Oxidative Stress, and Neurodegeneration by Modulating Cholinergic Activity and Oxidative Burden in Rat Brain.
Firdaus Z, Kumar D, Singh SK, Singh TD. Firdaus Z, et al. Biol Trace Elem Res. 2022 Dec;200(12):5115-5126. doi: 10.1007/s12011-021-03083-5. Epub 2022 Jan 4. Biol Trace Elem Res. 2022. PMID: 34984596
Aluminum (Al) is linked to the development of many neurological disorders such as Alzheimer's disease (AD), Parkinson's disease, and autism. Centella asiatica (CA) is a regenerating herb traditionally used to stimulate memory. This study was designed to assess the neuropro …
Aluminum (Al) is linked to the development of many neurological disorders such as Alzheimer's disease (AD), Parkinson's disease, and autism. …
28 results