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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 3
1981 8
1982 23
1983 33
1984 17
1985 23
1986 21
1987 18
1988 24
1989 19
1990 12
1991 25
1992 22
1993 27
1994 34
1995 45
1996 33
1997 37
1998 41
1999 24
2000 25
2001 25
2002 37
2003 28
2004 26
2005 23
2006 20
2007 24
2008 37
2009 41
2010 35
2011 33
2012 39
2013 25
2014 16
2015 30
2016 24
2017 23
2018 20
2019 19
2020 17
2021 22
2022 16
2023 16
2024 17

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1,072 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Antiviral treatment for acute retinal necrosis: A systematic review and meta-analysis.
Putera I, Ridwan AS, Dewi M, Cifuentes-González C, Rojas-Carabali W, Sitompul R, Edwar L, Susiyanti M, Aziza Y, Pavesio C, Chee SP, Mahendradas P, Biswas J, Kempen JH, Gupta V, de-la-Torre A, La Distia Nora R, Agrawal R. Putera I, et al. Surv Ophthalmol. 2024 Jan-Feb;69(1):67-84. doi: 10.1016/j.survophthal.2023.09.004. Epub 2023 Sep 27. Surv Ophthalmol. 2024. PMID: 37774799 Free article. Review.
Once-daily valacyclovir to reduce the risk of transmission of genital herpes.
Corey L, Wald A, Patel R, Sacks SL, Tyring SK, Warren T, Douglas JM Jr, Paavonen J, Morrow RA, Beutner KR, Stratchounsky LS, Mertz G, Keene ON, Watson HA, Tait D, Vargas-Cortes M; Valacyclovir HSV Transmission Study Group. Corey L, et al. N Engl J Med. 2004 Jan 1;350(1):11-20. doi: 10.1056/NEJMoa035144. N Engl J Med. 2004. PMID: 14702423 Free article. Clinical Trial.
Kanuka honey versus aciclovir for the topical treatment of herpes simplex labialis: a randomised controlled trial.
Semprini A, Singer J, Braithwaite I, Shortt N, Thayabaran D, McConnell M, Weatherall M, Beasley R. Semprini A, et al. BMJ Open. 2019 May 14;9(5):e026201. doi: 10.1136/bmjopen-2018-026201. BMJ Open. 2019. PMID: 31092654 Free PMC article. Clinical Trial.
OBJECTIVE: To compare New Zealand medical grade kanuka honey with topical aciclovir for the treatment of herpes simplex labialis. DESIGN: Prospective parallel randomised controlled open-label superiority trial. ...CONCLUSION: There was no evidence of a difference in effica …
OBJECTIVE: To compare New Zealand medical grade kanuka honey with topical aciclovir for the treatment of herpes simplex labialis. DES …
Acyclovir in shingles.
Bean B, Aeppli D, Balfour HH Jr. Bean B, et al. J Antimicrob Chemother. 1983 Sep;12 Suppl B:123-7. doi: 10.1093/jac/12.suppl_b.123. J Antimicrob Chemother. 1983. PMID: 6355047 Review.
Acyclovir given intravenously in either low dose (5 mg/kg every 8 h) or high dose (500 mg/m2 every 8 h) significantly reduced pain and accelerated skin healing in acute herpes zoster occurring in otherwise healthy adults. ...No adverse effects were associated with the lowe
Acyclovir given intravenously in either low dose (5 mg/kg every 8 h) or high dose (500 mg/m2 every 8 h) significantly reduced pain an
Lack of bioequivalence between two aciclovir tablets in healthy subjects.
Amini H, Javan M, Gazerani P, Ghaffari A, Ahmadiani A. Amini H, et al. Clin Drug Investig. 2008;28(1):47-53. doi: 10.2165/00044011-200828010-00006. Clin Drug Investig. 2008. PMID: 18081360 Clinical Trial.
OBJECTIVE: This study aimed to compare the systemic bioavailability of two aciclovir tablets, Rouz-Aciclovir (test) and Zovirax (reference), in 12 healthy volunteers. METHODS: In a crossover design, each subject received a single oral dose of aciclovir 400 mg …
OBJECTIVE: This study aimed to compare the systemic bioavailability of two aciclovir tablets, Rouz-Aciclovir (test) and Zovira …
Comparable aciclovir exposures produced by oral valaciclovir and intravenous aciclovir in immunocompromised cancer patients.
Höglund M, Ljungman P, Weller S. Höglund M, et al. J Antimicrob Chemother. 2001 Jun;47(6):855-61. doi: 10.1093/jac/47.6.855. J Antimicrob Chemother. 2001. PMID: 11389118 Clinical Trial.
The objective of this study was to evaluate the comparability of systemic aciclovir exposure at steady state in immunocompromised patients following oral valaciclovir 1000 mg tds and intravenous (iv) aciclovir 5 mg/kg tds. ...The mean absolute bioavailability of …
The objective of this study was to evaluate the comparability of systemic aciclovir exposure at steady state in immunocompromised pat …
Effect of aciclovir on HIV-1 acquisition in herpes simplex virus 2 seropositive women and men who have sex with men: a randomised, double-blind, placebo-controlled trial.
Celum C, Wald A, Hughes J, Sanchez J, Reid S, Delany-Moretlwe S, Cowan F, Casapia M, Ortiz A, Fuchs J, Buchbinder S, Koblin B, Zwerski S, Rose S, Wang J, Corey L; HPTN 039 Protocol Team. Celum C, et al. Lancet. 2008 Jun 21;371(9630):2109-19. doi: 10.1016/S0140-6736(08)60920-4. Lancet. 2008. PMID: 18572080 Free PMC article. Clinical Trial.
Incidence of genital ulcers on examination was reduced by 47% (relative risk 0.53 [0.46-0.62]) and HSV-2 positive genital ulcers by 63% (0.37 [0.31-0.45]) in the aciclovir group. Adherence to dispensed study drug was 94% in the aciclovir group and 94% in the placebo …
Incidence of genital ulcers on examination was reduced by 47% (relative risk 0.53 [0.46-0.62]) and HSV-2 positive genital ulcers by 63% (0.3 …
WITHDRAWN: Acyclovir for treating primary herpetic gingivostomatitis.
Nasser M, Fedorowicz Z, Khoshnevisan MH, Shahiri Tabarestani M. Nasser M, et al. Cochrane Database Syst Rev. 2016 Jan 19;2016(1):CD006700. doi: 10.1002/14651858.CD006700.pub3. Cochrane Database Syst Rev. 2016. PMID: 26784280 Free PMC article. Review.
Valaciclovir versus aciclovir in patient initiated treatment of recurrent genital herpes: a randomised, double blind clinical trial. International Valaciclovir HSV Study Group.
Bodsworth NJ, Crooks RJ, Borelli S, Vejlsgaard G, Paavonen J, Worm AM, Uexkull N, Esmann J, Strand A, Ingamells AJ, Gibb A. Bodsworth NJ, et al. Genitourin Med. 1997 Apr;73(2):110-6. doi: 10.1136/sti.73.2.110. Genitourin Med. 1997. PMID: 9215092 Free PMC article. Clinical Trial.
The hazard ratio [95% confidence interval] for valaciclovir v aciclovir was 0.93 [0.79, 1.08]. Lesion healing time was similar in each treatment group (hazard ratio valaciclovir v aciclovir 0.96 [0.80, 1.14]). The odds ratio of valaciclovir v aciclovir in pre …
The hazard ratio [95% confidence interval] for valaciclovir v aciclovir was 0.93 [0.79, 1.08]. Lesion healing time was similar in eac …
A Network Meta-Analysis of Randomized Clinical Trials to Assess the Efficacy and Safety of Antiviral Agents for Immunocompetent Patients with Herpes Zoster-Associated Pain.
Liu Y, Xiao S, Li J, Long X, Zhang Y, Li X. Liu Y, et al. Pain Physician. 2023 Jul;26(4):337-346. Pain Physician. 2023. PMID: 37535772 Free article.
According to the results of the network meta-analysis, for the treatment of acute pain, there was no significant difference between oral acyclovir and intravenous acyclovir. Furthermore, oral famciclovir was the most effective treatment concerning both the odds rati …
According to the results of the network meta-analysis, for the treatment of acute pain, there was no significant difference between oral …
1,072 results