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Pruritus as a Distinctive Feature of Type 2 Inflammation.
Garcovich S, Maurelli M, Gisondi P, Peris K, Yosipovitch G, Girolomoni G. Garcovich S, et al. Vaccines (Basel). 2021 Mar 23;9(3):303. doi: 10.3390/vaccines9030303. Vaccines (Basel). 2021. PMID: 33807098 Free PMC article. Review.
Pruritus is a common symptom of several skin diseases, both inflammatory and neoplastic. ...In contrast, in other skin diseases, such as scleroderma, lupus erythematosus, hidradenitis suppurativa, and acne, type 2 inflammation is less represented, and prur …
Pruritus is a common symptom of several skin diseases, both inflammatory and neoplastic. ...In contrast, in other skin diseases, such …
What causes hidradenitis suppurativa ?-15 years after.
Zouboulis CC, Benhadou F, Byrd AS, Chandran NS, Giamarellos-Bourboulis EJ, Fabbrocini G, Frew JW, Fujita H, González-López MA, Guillem P, Gulliver WPF, Hamzavi I, Hayran Y, Hórvath B, Hüe S, Hunger RE, Ingram JR, Jemec GBE, Ju Q, Kimball AB, Kirby JS, Konstantinou MP, Lowes MA, MacLeod AS, Martorell A, Marzano AV, Matusiak Ł, Nassif A, Nikiphorou E, Nikolakis G, Nogueira da Costa A, Okun MM, Orenstein LAV, Pascual JC, Paus R, Perin B, Prens EP, Röhn TA, Szegedi A, Szepietowski JC, Tzellos T, Wang B, van der Zee HH. Zouboulis CC, et al. Exp Dermatol. 2020 Dec;29(12):1154-1170. doi: 10.1111/exd.14214. Exp Dermatol. 2020. PMID: 33058306 Free article. Review.
Efficacy and safety of upadacitinib versus dupilumab in adults and adolescents with moderate-to-severe atopic dermatitis: week 16 results of an open-label randomized efficacy assessor-blinded head-to-head phase IIIb/IV study (Level Up).
Silverberg JI, Bunick CG, Hong HC, Mendes-Bastos P, Stein Gold L, Costanzo A, Ibrahim N, Sancho C, Wu X, Han Y, Levy G, Altman K, Calimlim B, Eyerich K. Silverberg JI, et al. Br J Dermatol. 2024 Dec 23;192(1):36-45. doi: 10.1093/bjd/ljae404. Br J Dermatol. 2024. PMID: 39438067 Free article. Clinical Trial.
Patients taking upadacitinib were more likely to have acne, headache, colds or certain types of infections, including shingles and a skin infection called eczema herpeticum, than patients taking dupilumab. Patients taking dupilumab were more likely to have inflammation …
Patients taking upadacitinib were more likely to have acne, headache, colds or certain types of infections, including shingles and a …
Once-daily upadacitinib versus placebo in adolescents and adults with moderate-to-severe atopic dermatitis (Measure Up 1 and Measure Up 2): results from two replicate double-blind, randomised controlled phase 3 trials.
Guttman-Yassky E, Teixeira HD, Simpson EL, Papp KA, Pangan AL, Blauvelt A, Thaçi D, Chu CY, Hong HC, Katoh N, Paller AS, Calimlim B, Gu Y, Hu X, Liu M, Yang Y, Liu J, Tenorio AR, Chu AD, Irvine AD. Guttman-Yassky E, et al. Lancet. 2021 Jun 5;397(10290):2151-2168. doi: 10.1016/S0140-6736(21)00588-2. Epub 2021 May 21. Lancet. 2021. PMID: 34023008 Clinical Trial.
Eligible patients were adolescents (aged 12-17 years) and adults (aged 18-75 years) with moderate-to-severe atopic dermatitis ( 10% of body surface area affected by atopic dermatitis, Eczema Area and Severity Index [EASI] score of 16, validated Investigator's Global Assessment f …
Eligible patients were adolescents (aged 12-17 years) and adults (aged 18-75 years) with moderate-to-severe atopic dermatitis ( 10% of body …
Cannabis and the skin.
Shao K, Stewart C, Grant-Kels JM. Shao K, et al. Clin Dermatol. 2021 Sep-Oct;39(5):784-795. doi: 10.1016/j.clindermatol.2021.05.006. Epub 2021 May 14. Clin Dermatol. 2021. PMID: 34785006 Review.
In vitro and in vivo studies of Cannabis have suggested it has favorable effects on regulating pain, pruritus, and inflammation, making it a potentially attractive therapeutic agent for many dermatologic conditions. ...We review the current research, possible cutane …
In vitro and in vivo studies of Cannabis have suggested it has favorable effects on regulating pain, pruritus, and inflammation …
Adverse Events Associated with Apremilast and Deucravacitinib for Psoriasis: A Pharmacovigilance Study Based on the FAERS Database.
Xu Y, Liu X, Guo L, Jiang X. Xu Y, et al. Clin Cosmet Investig Dermatol. 2025 May 5;18:1121-1135. doi: 10.2147/CCID.S439643. eCollection 2025. Clin Cosmet Investig Dermatol. 2025. PMID: 40351849 Free PMC article.
Deucravacitinib showed stronger associations with cutaneous AEs, including acne, folliculitis, pruritus, rash, and erythema, along with oral conditions. AEs not previously documented on drug labels, such as sinus headache and multiple allergies for apremilast, and a …
Deucravacitinib showed stronger associations with cutaneous AEs, including acne, folliculitis, pruritus, rash, and erythema, a …
Zidovudine-induced leukocytoclastic vasculitis.
Torres RA, Lin RY, Lee M, Barr MR. Torres RA, et al. Arch Intern Med. 1992 Apr;152(4):850-1. Arch Intern Med. 1992. PMID: 1558446
Cutaneous reactions, including acne, pruritus, urticaria, and nail dyschromia, have been associated with zidovudine use. Cutaneous leukocytoclastic vasculitis is characterized by distinctive patterns of dermal perivascular inflammation without visceral involv …
Cutaneous reactions, including acne, pruritus, urticaria, and nail dyschromia, have been associated with zidovudine use. Cutan …
The expression of pruritus-associated genes in seven skin diseases: Evidence from microarray.
Alsabbagh MM. Alsabbagh MM. J Eur Acad Dermatol Venereol. 2026 Mar;40(3):464-472. doi: 10.1111/jdv.70109. Epub 2025 Oct 13. J Eur Acad Dermatol Venereol. 2026. PMID: 41081460
BACKGROUND: Pruritus may accompany different skin diseases including atopic dermatitis, lichen planus, psoriasis, cutaneous lupus erythematosus, acne, alopecia areata and rosacea. ...We searched the Gene Set Enrichment Analysis-Molecular Signatures database to obtai …
BACKGROUND: Pruritus may accompany different skin diseases including atopic dermatitis, lichen planus, psoriasis, cutaneous lupus ery …
Therapeutic textiles: A promising approach for human skin dysbiosis?
de Oliveira CSF, Tavaria FK. de Oliveira CSF, et al. Exp Dermatol. 2024 Apr;33(4):e15081. doi: 10.1111/exd.15081. Exp Dermatol. 2024. PMID: 38628046
Skin microbiota imbalance is known in several skin diseases, including atopic dermatitis (AD), psoriasis, seborrheic dermatitis, rosacea, acne and hidradenitis suppurative (HS). Such microbiota dysregulation is usually correlated with inflammation, discomfort and …
Skin microbiota imbalance is known in several skin diseases, including atopic dermatitis (AD), psoriasis, seborrheic dermatitis, rosacea, …
Hypochlorous Acid: Clinical Insights and Experience in Dermatology, Surgery, Dentistry, Ophthalmology, Rhinology, and Other Specialties.
Haralović V, Mokos M, Špoljar S, Dolački L, Šitum M, Lugović-Mihić L. Haralović V, et al. Biomedicines. 2025 Nov 28;13(12):2921. doi: 10.3390/biomedicines13122921. Biomedicines. 2025. PMID: 41462936 Free PMC article. Review.
Results: Due to its anti-inflammatory/antimicrobial/immunomodulatory and healing properties, HOCl is advantageous in treating various skin disorders: ulcus cruris (and wound care), diabetic ulcers, atopic dermatitis, seborrheic dermatitis, pruritus, acne vulgaris …
Results: Due to its anti-inflammatory/antimicrobial/immunomodulatory and healing properties, HOCl is advantageous in treating various skin d …
29 results