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1971 1
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154 results

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Page 1
The copolymer of Poly(2-dimethylaminoethyl methacrylate) and methacrylated chondroitin sulfate with low cytotoxicity for gene delivery.
Lo YL, Wang YS, Wang LF. Lo YL, et al. Adv Healthc Mater. 2013 Nov;2(11):1458-68. doi: 10.1002/adhm.201200373. Epub 2013 Apr 25. Adv Healthc Mater. 2013. PMID: 23616370
Poly(2-dimethylaminoethyl methacrylate) (PDMAEMA) is one of the most potent synthetic nonviral gene-delivery vectors because of its high transfection efficiency. ...An anionic crosslinker is synthesized based on a natural polysaccharide, chondroitin sulfate (CS), by …
Poly(2-dimethylaminoethyl methacrylate) (PDMAEMA) is one of the most potent synthetic nonviral gene-delivery vectors because o …
Dissolution Behavior of Weakly Basic Pharmaceuticals from Amorphous Dispersions Stabilized by a Poly(dimethylaminoethyl Methacrylate) Copolymer.
Frank DS, Prasad P, Iuzzolino L, Schenck L. Frank DS, et al. Mol Pharm. 2022 Sep 5;19(9):3304-3313. doi: 10.1021/acs.molpharmaceut.2c00456. Epub 2022 Aug 19. Mol Pharm. 2022. PMID: 35985017
This work examines the release mechanisms of amorphous dispersions containing model weakly basic pharmaceuticals posaconazole and lumefantrine from a basic poly(dimethylaminoethyl methacrylate) copolymer (Eudragit EPO) and compares their dissolution behavior …
This work examines the release mechanisms of amorphous dispersions containing model weakly basic pharmaceuticals posaconazole and lumefantri …
Stimuli-Responsive Nanodiamond-Polyelectrolyte Composite Films.
Tiainen T, Lobanova M, Karjalainen E, Tenhu H, Hietala S. Tiainen T, et al. Polymers (Basel). 2020 Feb 26;12(3):507. doi: 10.3390/polym12030507. Polymers (Basel). 2020. PMID: 32110929 Free PMC article.
In this work, tough, flexible, and stimuli-responsive polyelectrolyte films composed of cross-linked poly(butyl acrylate-co-dimethylaminoethyl methacrylate) (P(BA-co-DMAEMA)) were prepared by photopolymerization. ...In order to disperse and distribute the NDs …
In this work, tough, flexible, and stimuli-responsive polyelectrolyte films composed of cross-linked poly(butyl acrylate-co-dimeth
Synthesis and characterization of thermo/pH-sensitive pectin-graft-poly(dimethylaminoethyl methacrylate) coated magnetic nanoparticles.
Işıklan N, Polat S. Işıklan N, et al. Int J Biol Macromol. 2020 Dec 1;164:4499-4515. doi: 10.1016/j.ijbiomac.2020.09.002. Epub 2020 Sep 6. Int J Biol Macromol. 2020. PMID: 32898537
Herein, thermo- and pH-sensitive pectin-graft-poly(dimethylaminoethyl methacrylate) copolymer-coated magnetic nanoparticles were synthesized via a green and rapid synthetic approach based on microwave irradiation. Firstly, a novel thermo- and pH-sensitive pec …
Herein, thermo- and pH-sensitive pectin-graft-poly(dimethylaminoethyl methacrylate) copolymer-coated magnetic nanoparti …
Interpenetrating polymer network systems based on poly(dimethylaminoethyl methacrylate) and a copolymer containing pendant spiroacetal moieties.
Nita LE, Chiriac AP, Rusu AG, Bercea M, Diaconu A, Tudorachi N. Nita LE, et al. Mater Sci Eng C Mater Biol Appl. 2018 Jun 1;87:22-31. doi: 10.1016/j.msec.2018.02.016. Epub 2018 Feb 21. Mater Sci Eng C Mater Biol Appl. 2018. PMID: 29549946
In this context, in the present study, new IPN structures based on poly(dimethylaminoethyl methacrylate) (PDMAEMA) and poly(itaconic anhydride-co-3,9-divinyl-2,4,8,10-tetraoxaspiro[5.5] undecane) (PITAU) were synthesized. ...
In this context, in the present study, new IPN structures based on poly(dimethylaminoethyl methacrylate) (PDMAEMA) and poly(it …
Oxygen-nitrogen switchable copolymers of 2,2,2-trifluoroethyl methacrylate and n,n-dimethylaminoethyl methacrylate.
Zhang Q, Zhu S. Zhang Q, et al. Macromol Rapid Commun. 2014 Oct;35(19):1692-6. doi: 10.1002/marc.201400346. Epub 2014 Sep 1. Macromol Rapid Commun. 2014. PMID: 25179665
In this work, a novel class of O2 /N2 switchable polymers is reported, which is prepared by atom transfer radical copolymerization (ATRcoP) of commercially available 2,2,2-trifluoroethyl methacrylate (FMA) and N,N-dimethylaminoethyl methacrylate (DMA). The …
In this work, a novel class of O2 /N2 switchable polymers is reported, which is prepared by atom transfer radical copolymerization (ATRcoP) …
Unexpected Solubility Enhancement of Drug Bases in the Presence of a Dimethylaminoethyl Methacrylate Copolymer.
Saal W, Ross A, Wyttenbach N, Alsenz J, Kuentz M. Saal W, et al. Mol Pharm. 2018 Jan 2;15(1):186-192. doi: 10.1021/acs.molpharmaceut.7b00804. Epub 2017 Dec 6. Mol Pharm. 2018. PMID: 29164891
The methacrylate copolymer Eudragit EPO (EPO) has previously shown to greatly enhance solubilization of acidic drugs via ionic interactions and by multiple hydrophobic contacts with polymeric side chains. ...
The methacrylate copolymer Eudragit EPO (EPO) has previously shown to greatly enhance solubilization of acidic drugs via ionic …
Interactions of dimethylaminoethyl methacrylate copolymer with non-acidic drugs demonstrated high solubilization in vitro and pronounced sustained release in vivo.
Saal W, Wyttenbach N, Alsenz J, Kuentz M. Saal W, et al. Eur J Pharm Biopharm. 2018 Apr;125:68-75. doi: 10.1016/j.ejpb.2018.01.006. Epub 2018 Jan 10. Eur J Pharm Biopharm. 2018. PMID: 29331439
Recent work demonstrated remarkable solubilization effects of methacrylate-copolymer Eudragit EPO (EPO) not only with acidic drugs but interestingly also with poorly soluble basic compounds. ...
Recent work demonstrated remarkable solubilization effects of methacrylate-copolymer Eudragit EPO (EPO) not only with acidic d …
Controlled drug dissolution by radiation-induced polymerization in the presence of dimethylaminoethyl methacrylate-methyl methacrylate copolymer or methacrylic acid-methyl acrylate copolymer.
Yoshida M, Kumakura M, Kaetsu I. Yoshida M, et al. J Pharm Sci. 1979 Jul;68(7):860-2. doi: 10.1002/jps.2600680719. J Pharm Sci. 1979. PMID: 458603
Polymer-containing tablet preparation was studied using radiation-induced polymerization of glass-forming monomers at low temperatures in the presence of dimethylaminoethyl methacrylate-methyl methacrylate copolymer or methyl acrylate-methacr
Polymer-containing tablet preparation was studied using radiation-induced polymerization of glass-forming monomers at low temperatures in th …
154 results