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Page 1
Growth inhibitory activity of extracts and purified components of black cohosh on human breast cancer cells.
Einbond LS, Shimizu M, Xiao D, Nuntanakorn P, Lim JT, Suzui M, Seter C, Pertel T, Kennelly EJ, Kronenberg F, Weinstein IB. Einbond LS, et al. Breast Cancer Res Treat. 2004 Feb;83(3):221-31. doi: 10.1023/B:BREA.0000014043.56230.a3. Breast Cancer Res Treat. 2004. PMID: 14758092
The triterpene glycoside fraction obtained by polyamide column chromatography, and the specific triterpene glycosides actein, 23-epi-26-deoxyactein and cimiracemoside A, inhibited growth of the MCF7 human breast cancer cells and induced cell cycle arrest at G1. ...F …
The triterpene glycoside fraction obtained by polyamide column chromatography, and the specific triterpene glycosides actein, 23-epi- …
Quantitative determination of triterpenoids and formononetin in rhizomes of black cohosh (Actaea racemosa) and dietary supplements by using UPLC-UV/ELS detection and identification by UPLC-MS.
Avula B, Wang YH, Smillie TJ, Khan IA. Avula B, et al. Planta Med. 2009 Mar;75(4):381-6. doi: 10.1055/s-0028-1088384. Epub 2008 Dec 5. Planta Med. 2009. PMID: 19061153
Within 5.5 minutes, three main triterpenoid glycosides [cimiracemoside A, 23- EPI-26-deoxyactein, and actein] and an isoflavonoid, formononetin, could be separated, with detection limits of 5, 5, 10, and 0.01 microg/mL, respectively. ...
Within 5.5 minutes, three main triterpenoid glycosides [cimiracemoside A, 23- EPI-26-deoxyactein, and actein] and an isoflavon …
Development of a fast and convenient method for the isolation of triterpene saponins from Actaea racemosa by high-speed countercurrent chromatography coupled with evaporative light scattering detection.
Cicek SS, Schwaiger S, Ellmerer EP, Stuppner H. Cicek SS, et al. Planta Med. 2010 Mar;76(5):467-73. doi: 10.1055/s-0029-1186236. Epub 2009 Oct 21. Planta Med. 2010. PMID: 19847744
Size exclusion chromatography was used to separate actein and 23-epi-26-deoxyactein from other triterpenoids, which were collected in a third fraction. ...The same method was suitable for the purification of actein and 23-epi-26-deoxyactein, with purities of 97.0 % …
Size exclusion chromatography was used to separate actein and 23-epi-26-deoxyactein from other triterpenoids, which were collected in …
Oral administration of Cimicifuga racemosa extract attenuates immobilization stress-induced reactions.
Nadaoka I, Watanabe K, Yasue M, Sami M, Kitagawa Y, Mimaki Y. Nadaoka I, et al. Nat Prod Commun. 2012 Jan;7(1):15-8. Nat Prod Commun. 2012. PMID: 22428232
Bioassay-guided fractionation of the CR extract resulted in the isolation of 10 triterpenes, among which actein, 23-epi-26-deoxyactein, and cimiracemoside F (100 mg/kg, per os) were shown to contribute to the anti-stress effects. ...
Bioassay-guided fractionation of the CR extract resulted in the isolation of 10 triterpenes, among which actein, 23-epi-26-deoxyactei …
In vivo effects of black cohosh and genistein on estrogenic activity and lipid peroxidation in Japanese Medaka (Oryzias latipes).
Zhang L, Khan IA, Willett KL, Foran CM. Zhang L, et al. J Herb Pharmacother. 2003;3(3):33-50. J Herb Pharmacother. 2003. PMID: 15277055
While both genistein and estradiol altered ovarian and testicular steroid release and decreased circulating testosterone levels in males, neither black cohosh total extract (75-30,000 ng/fish), cimiracemoside A, 25-O-methyl-cimigenoside, actein, nor 26-deoxy-acte …
While both genistein and estradiol altered ovarian and testicular steroid release and decreased circulating testosterone levels in males, ne …