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Page 1
Field cancerization: Definition, epidemiology, risk factors, and outcomes.
Willenbrink TJ, Ruiz ES, Cornejo CM, Schmults CD, Arron ST, Jambusaria-Pahlajani A. Willenbrink TJ, et al. J Am Acad Dermatol. 2020 Sep;83(3):709-717. doi: 10.1016/j.jaad.2020.03.126. Epub 2020 May 7. J Am Acad Dermatol. 2020. PMID: 32387665 Review.
Since this initial study, field cancerization has been applied to numerous other epithelial tissues, including the skin. Cutaneous field cancerization occurs in areas exposed to chronic ultraviolet radiation, which leads to clonal proliferations of p53 …
Since this initial study, field cancerization has been applied to numerous other epithelial tissues, including the skin. Cutan …
Field Cancerization Therapies for the Management of Actinic Keratosis: An Updated Review.
Aggarwal I, Puyana C, Chandan N, Jetter N, Tsoukas M. Aggarwal I, et al. Am J Clin Dermatol. 2024 May;25(3):391-405. doi: 10.1007/s40257-023-00839-8. Epub 2024 Feb 13. Am J Clin Dermatol. 2024. PMID: 38351246 Review.
Field cancerization theory highlights that the skin surrounding actinic keratoses (AK) is also at increased risk for possible malignant transformation; thus, field-directed treatments may both reduce the risk of AK recurrence and potentially reduce the
Field cancerization theory highlights that the skin surrounding actinic keratoses (AK) is also at increased risk for po
European consensus-based interdisciplinary guideline for diagnosis, treatment and prevention of actinic keratoses, epithelial UV-induced dysplasia and field cancerization on behalf of European Association of Dermato-Oncology, European Dermatology Forum, European Academy of Dermatology and Venereology and Union of Medical Specialists (Union Europeenne des Medecins Specialistes).
Kandolf L, Peris K, Malvehy J, Mosterd K, Heppt MV, Fargnoli MC, Berking C, Arenberger P, Bylaite-Bučinskiene M, Del Marmol V, Dirschka T, Dreno B, Forsea AM, Harwood CA, Hauschild A, Heerfordt IM, Kauffman R, Kelleners-Smeets N, Lallas A, Lebbe C, Leiter U, Longo C, Mijušković Ž, Pellacani G, Puig S, Saiag P, Šitum M, Stockfleth E, Salavastru C, Stratigos A, Zalaudek I, Garbe C; European Association of Dermato‐Oncology, European Dermatology Forum, European Academy of Dermatology and Venereology and Union of Medical Specialists (Union Européenne des Médecins Spécialistes). Kandolf L, et al. J Eur Acad Dermatol Venereol. 2024 Jun;38(6):1024-1047. doi: 10.1111/jdv.19897. Epub 2024 Mar 7. J Eur Acad Dermatol Venereol. 2024. PMID: 38451047 Free article.
The diagnosis of AK and field cancerization is made by clinical examination. Dermatoscopy, confocal microscopy, optical coherence tomography or line-field confocal-OCT can help in the differential diagnosis of AK and other skin neoplasms. ...Preventive …
The diagnosis of AK and field cancerization is made by clinical examination. Dermatoscopy, confocal microscopy, optical cohere …
Current therapies for actinic keratosis.
Dianzani C, Conforti C, Giuffrida R, Corneli P, di Meo N, Farinazzo E, Moret A, Magaton Rizzi G, Zalaudek I. Dianzani C, et al. Int J Dermatol. 2020 Jun;59(6):677-684. doi: 10.1111/ijd.14767. Epub 2020 Feb 3. Int J Dermatol. 2020. PMID: 32012240 Free article. Review.
Actinic keratosis (AK) is a very common skin disease caused by chronic sun damage, which in 75% of cases arises on chronically sun-exposed areas, such as face, scalp, neck, hands, and forearms. ...Whereas, field-directed treatments are: (i) 5-fluorouracil (5-
Actinic keratosis (AK) is a very common skin disease caused by chronic sun damage, which in 75% of cases arises on chronically
Treatment of actinic keratosis: a systematic review.
Worley B, Harikumar V, Reynolds K, Dirr MA, Christensen RE, Anvery N, Yi MD, Poon E, Alam M. Worley B, et al. Arch Dermatol Res. 2023 Jul;315(5):1099-1108. doi: 10.1007/s00403-022-02490-5. Epub 2022 Dec 1. Arch Dermatol Res. 2023. PMID: 36454335
Treatment of actinic keratoses (AKs) can help lower the risk of eventual skin cancer and address field pre-cancerization. This review compares the different therapeutic options for actinic keratosis. Databases used include Medline, EMBASE …
Treatment of actinic keratoses (AKs) can help lower the risk of eventual skin cancer and address field pre-canceriza
Field Cancerization Therapies for Management of Actinic Keratosis: A Narrative Review.
Jetter N, Chandan N, Wang S, Tsoukas M. Jetter N, et al. Am J Clin Dermatol. 2018 Aug;19(4):543-557. doi: 10.1007/s40257-018-0348-7. Am J Clin Dermatol. 2018. PMID: 29582369 Review.
Actinic keratoses (AKs) are atypical, precancerous proliferations of keratinocytes that develop because of chronic exposure to ultraviolet (UV) radiation. Treatment of AK can be lesion-directed or field-directed. Field cancerization theory postulates t
Actinic keratoses (AKs) are atypical, precancerous proliferations of keratinocytes that develop because of chronic exposure to ultrav
Field cancerization: Treatment.
Cornejo CM, Jambusaria-Pahlajani A, Willenbrink TJ, Schmults CD, Arron ST, Ruiz ES. Cornejo CM, et al. J Am Acad Dermatol. 2020 Sep;83(3):719-730. doi: 10.1016/j.jaad.2020.03.127. Epub 2020 May 6. J Am Acad Dermatol. 2020. PMID: 32387663 Review.
The goal of field cancerization treatment is to reduce the risk of developing keratinocyte carcinoma. ...The second article in this continuing medical education series provides a framework to guide evidence-based decision making for field cancerization
The goal of field cancerization treatment is to reduce the risk of developing keratinocyte carcinoma. ...The second article in …
Daylight Photodynamic Therapy for Actinic Keratosis and Field Cancerization: A Narrative Review.
Sotiriou E, Kiritsi D, Chaitidis N, Arabatzis M, Lallas A, Vakirlis E. Sotiriou E, et al. Cancers (Basel). 2025 Mar 20;17(6):1050. doi: 10.3390/cancers17061050. Cancers (Basel). 2025. PMID: 40149382 Free PMC article. Review.
Actinic keratoses (AKs), also known as solar keratoses, are rough, scaly lesions that appear as macules, papules, or plaques [...]....
Actinic keratoses (AKs), also known as solar keratoses, are rough, scaly lesions that appear as macules, papules, or plaques [...]...
Field cancerization in clinically solitary actinic keratosis: A pilot study.
Micali G, Verzì AE, Barresi S, Dirschka T, Lacarrubba F. Micali G, et al. Dermatol Ther. 2021 Jan;34(1):e14607. doi: 10.1111/dth.14607. Epub 2020 Dec 9. Dermatol Ther. 2021. PMID: 33249729
Clinical studies have demonstrated that subclinical actinic keratoses (AKs) may be clinically evidenced following treatment of multiple AKs with a topical immunotherapy agent known to reveal a "field cancerization". ...At the end of treatment, subclinical les …
Clinical studies have demonstrated that subclinical actinic keratoses (AKs) may be clinically evidenced following treatment of multip …
[Actinic keratosis].
Heppt MV, Steeb T, Szeimies RM, Berking C. Heppt MV, et al. Hautarzt. 2020 Aug;71(8):588-596. doi: 10.1007/s00105-020-04612-4. Hautarzt. 2020. PMID: 32468291 Review. German.
Actinic keratoses (AK) are common precancerous cutaneous lesions in fair-skinned individuals as a result of cumulative exposure to ultraviolet radiation. ...As AK may potentially progress into invasive cutaneous squamous cell carcinoma, guidelines recommend early and conse
Actinic keratoses (AK) are common precancerous cutaneous lesions in fair-skinned individuals as a result of cumulative exposure to ul
657 results