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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 1
1980 1
1981 6
1982 4
1983 8
1984 10
1985 11
1986 11
1987 6
1988 6
1989 12
1990 9
1991 5
1992 6
1993 2
1994 7
1995 5
1996 5
1997 10
1998 12
1999 11
2000 9
2001 18
2002 10
2003 11
2004 13
2005 8
2006 16
2007 9
2008 13
2009 17
2010 23
2011 45
2012 60
2013 79
2014 99
2015 134
2016 140
2017 150
2018 169
2019 171
2020 86
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Page 1
Brown adipose tissue and thermogenesis.
Fenzl A, Kiefer FW. Fenzl A, et al. Horm Mol Biol Clin Investig. 2014 Jul;19(1):25-37. doi: 10.1515/hmbci-2014-0022. Horm Mol Biol Clin Investig. 2014. PMID: 25390014 Free article. Review.
Brown adipose tissue (BAT), in contrast to bona fide white fat, can dissipate significant amounts of chemical energy through uncoupled respiration and heat production (thermogenesis). ...White adipose tissue (WAT) depots, however, also po
Brown adipose tissue (BAT), in contrast to bona fide white fat, can dissipate significant amounts of chemical energy th
Accumulation of succinate controls activation of adipose tissue thermogenesis.
Mills EL, Pierce KA, Jedrychowski MP, Garrity R, Winther S, Vidoni S, Yoneshiro T, Spinelli JB, Lu GZ, Kazak L, Banks AS, Haigis MC, Kajimura S, Murphy MP, Gygi SP, Clish CB, Chouchani ET. Mills EL, et al. Nature. 2018 Aug;560(7716):102-106. doi: 10.1038/s41586-018-0353-2. Epub 2018 Jul 18. Nature. 2018. PMID: 30022159 Free PMC article.
Thermogenesis by brown and beige adipose tissue, which requires activation by external stimuli, can counter metabolic disease(1). ...Finally, we show that pharmacological elevation of circulating succinate drives UCP1-dependent thermogenesis
Thermogenesis by brown and beige adipose tissue, which requires activation by external stimuli, can count
Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation.
Wang G, Meyer JG, Cai W, Softic S, Li ME, Verdin E, Newgard C, Schilling B, Kahn CR. Wang G, et al. Mol Cell. 2019 May 16;74(4):844-857.e7. doi: 10.1016/j.molcel.2019.03.021. Epub 2019 Apr 15. Mol Cell. 2019. PMID: 31000437 Free PMC article.
Brown adipose tissue (BAT) is rich in mitochondria and plays important roles in energy expenditure, thermogenesis, and glucose homeostasis. ...Mutation of the two succinylated lysines in UCP1 to acyl-mimetic glutamine and glutamic acid significantly de
Brown adipose tissue (BAT) is rich in mitochondria and plays important roles in energy expenditure, thermogenesis
BCAA catabolism in brown fat controls energy homeostasis through SLC25A44.
Yoneshiro T, Wang Q, Tajima K, Matsushita M, Maki H, Igarashi K, Dai Z, White PJ, McGarrah RW, Ilkayeva OR, Deleye Y, Oguri Y, Kuroda M, Ikeda K, Li H, Ueno A, Ohishi M, Ishikawa T, Kim K, Chen Y, Sponton CH, Pradhan RN, Majd H, Greiner VJ, Yoneshiro M, Brown Z, Chondronikola M, Takahashi H, Goto T, Kawada T, Sidossis L, Szoka FC, McManus MT, Saito M, Soga T, Kajimura S. Yoneshiro T, et al. Nature. 2019 Aug;572(7771):614-619. doi: 10.1038/s41586-019-1503-x. Epub 2019 Aug 21. Nature. 2019. PMID: 31435015 Free PMC article.
Here we report that, on cold exposure, brown adipose tissue (BAT) actively utilizes BCAA in the mitochondria for thermogenesis and promotes systemic BCAA clearance in mice and humans. In turn, a BAT-specific defect in BCAA catabolism attenuates …
Here we report that, on cold exposure, brown adipose tissue (BAT) actively utilizes BCAA in the mitochondria for …
Brown Adipose Tissue: an Update on Recent Findings.
Marlatt KL, Ravussin E. Marlatt KL, et al. Curr Obes Rep. 2017 Dec;6(4):389-396. doi: 10.1007/s13679-017-0283-6. Curr Obes Rep. 2017. PMID: 29101739 Free PMC article. Review.
Given its potential role in stimulating energy expenditure, brown adipose tissue (BAT) activation has become a trending topic as an anti-obesity treatment. ...More research is needed to confirm the relevance of BAT and beige tissue to who …
Given its potential role in stimulating energy expenditure, brown adipose tissue (BAT) activation has become a t …
Brown Adipose Tissue Development and Metabolism.
Jung SM, Sanchez-Gurmaches J, Guertin DA. Jung SM, et al. Handb Exp Pharmacol. 2019;251:3-36. doi: 10.1007/164_2018_168. Handb Exp Pharmacol. 2019. PMID: 30203328 Free PMC article. Review.
Brown adipose tissue is well known to be a thermoregulatory organ particularly important in small rodents and human infants, but it was only recently that its existence and significance to metabolic fitness in adult humans have been widely realized. The abili
Brown adipose tissue is well known to be a thermoregulatory organ particularly important in small rodents and human inf
Contribution of brown adipose tissue to human energy metabolism.
Fernández-Verdejo R, Marlatt KL, Ravussin E, Galgani JE. Fernández-Verdejo R, et al. Mol Aspects Med. 2019 Aug;68:82-89. doi: 10.1016/j.mam.2019.07.003. Epub 2019 Jul 16. Mol Aspects Med. 2019. PMID: 31306668 Free PMC article. Review.
With the discovery of brown adipose tissue (BAT) in adult humans, BAT activation soon emerged as a potential strategy for elevating energy expenditure. ...Remarkable advances have been made in quantifying the amount and activity of BAT in humans …
With the discovery of brown adipose tissue (BAT) in adult humans, BAT activation soon emerged as a potential str …
Glucocorticoids and Brown Adipose Tissue: Do glucocorticoids really inhibit thermogenesis?
Luijten IHN, Cannon B, Nedergaard J. Luijten IHN, et al. Mol Aspects Med. 2019 Aug;68:42-59. doi: 10.1016/j.mam.2019.07.002. Epub 2019 Jul 27. Mol Aspects Med. 2019. PMID: 31323252 Free article. Review.
A reduction in the thermogenic activity of brown adipose tissue (BAT) is presently discussed as a possible determinant for the development of obesity in humans. ...It is thus unlikely that glucocorticoids affect organismal metabolism and induce …
A reduction in the thermogenic activity of brown adipose tissue (BAT) is presently discussed as a possible deter …
Berberine activates thermogenesis in white and brown adipose tissue.
Zhang Z, Zhang H, Li B, Meng X, Wang J, Zhang Y, Yao S, Ma Q, Jin L, Yang J, Wang W, Ning G. Zhang Z, et al. Nat Commun. 2014 Nov 25;5:5493. doi: 10.1038/ncomms6493. Nat Commun. 2014. PMID: 25423280
Obesity develops when energy intake exceeds energy expenditure. Promoting brown adipose tissue formation and function increases energy expenditure and hence may counteract obesity. ...Here we show that BBR increases energy expenditure, limits we
Obesity develops when energy intake exceeds energy expenditure. Promoting brown adipose tissue formation and fun
Adipose tissue browning and metabolic health.
Bartelt A, Heeren J. Bartelt A, et al. Nat Rev Endocrinol. 2014 Jan;10(1):24-36. doi: 10.1038/nrendo.2013.204. Epub 2013 Oct 22. Nat Rev Endocrinol. 2014. PMID: 24146030 Review.
Accumulation of excess white adipose tissue (WAT) has deleterious consequences for metabolic health. The activation of brown adipose tissue (BAT), the primary organ for heat production, confers beneficial effects on adiposity, insulin res …
Accumulation of excess white adipose tissue (WAT) has deleterious consequences for metabolic health. The activation of …
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