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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 1
1997 3
1998 7
1999 8
2000 10
2001 16
2002 15
2003 31
2004 34
2005 49
2006 41
2007 44
2008 37
2009 52
2010 56
2011 67
2012 62
2013 64
2014 71
2015 66
2016 63
2017 72
2018 52
2019 59
2020 36
2021 4
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Page 1
Association of High-Sensitivity Cardiac Troponin I Concentration With Cardiac Outcomes in Patients With Suspected Acute Coronary Syndrome.
Chapman AR, Lee KK, McAllister DA, Cullen L, Greenslade JH, Parsonage W, Worster A, Kavsak PA, Blankenberg S, Neumann J, Sörensen NA, Westermann D, Buijs MM, Verdel GJE, Pickering JW, Than MP, Twerenbold R, Badertscher P, Sabti Z, Mueller C, Anand A, Adamson P, Strachan FE, Ferry A, Sandeman D, Gray A, Body R, Keevil B, Carlton E, Greaves K, Korley FK, Metkus TS, Sandoval Y, Apple FS, Newby DE, Shah ASV, Mills NL. Chapman AR, et al. JAMA. 2017 Nov 21;318(19):1913-1924. doi: 10.1001/jama.2017.17488. JAMA. 2017. PMID: 29127948 Free PMC article. Review.
IMPORTANCE: High-sensitivity cardiac troponin I testing is widely used to evaluate patients with suspected acute coronary syndrome. ...OBJECTIVE: To evaluate the performance of a cardiac troponin I threshold of 5 ng/L at presentation as a risk s …
IMPORTANCE: High-sensitivity cardiac troponin I testing is widely used to evaluate patients with suspected acute coronary …
Cardiac troponins: from myocardial infarction to chronic disease.
Park KC, Gaze DC, Collinson PO, Marber MS. Park KC, et al. Cardiovasc Res. 2017 Dec 1;113(14):1708-1718. doi: 10.1093/cvr/cvx183. Cardiovasc Res. 2017. PMID: 29016754 Free PMC article. Review.
By exploiting cardiac-restricted epitopes within these proteins, one of the most successful diagnostic tests to date has been developed: cardiac troponin (cTn) assays. For the past decade, cTn has been regarded as the gold-standard marker for acute myocardial nec …
By exploiting cardiac-restricted epitopes within these proteins, one of the most successful diagnostic tests to date has been developed: car …
High-Sensitivity Cardiac Troponin for the Diagnosis of Patients with Acute Coronary Syndromes.
Vasile VC, Jaffe AS. Vasile VC, et al. Curr Cardiol Rep. 2017 Aug 24;19(10):92. doi: 10.1007/s11886-017-0904-4. Curr Cardiol Rep. 2017. PMID: 28840515 Review.
PURPOSE OF REVIEW: High-sensitivity cardiac troponin (hscTn) assays are replacing the older-generation assays used to detect myocardial injury because they have improved analytical sensitivity and lead to a more rapid diagnosis of acute myocardial infarction (AMI) a …
PURPOSE OF REVIEW: High-sensitivity cardiac troponin (hscTn) assays are replacing the older-generation assays used to detect myocardi …
A Randomized Trial of a 1-Hour Troponin T Protocol in Suspected Acute Coronary Syndromes: The Rapid Assessment of Possible Acute Coronary Syndrome in the Emergency Department With High-Sensitivity Troponin T Study (RAPID-TnT).
Chew DP, Lambrakis K, Blyth A, Seshadri A, Edmonds MJR, Briffa T, Cullen LA, Quinn S, Karnon J, Chuang A, Nelson AJ, Wright D, Horsfall M, Morton E, French JK, Papendick C. Chew DP, et al. Circulation. 2019 Nov 5;140(19):1543-1556. doi: 10.1161/CIRCULATIONAHA.119.042891. Epub 2019 Sep 3. Circulation. 2019. PMID: 31478763 Clinical Trial.
This multicenter study evaluated the noninferiority of a 0/1-hour high-sensitivity cardiac troponin T (hs-cTnT) protocol in comparison with a 0/3-hour masked hs-cTnT protocol in patients with suspected acute coronary syndrome presenting to the emergenc …
This multicenter study evaluated the noninferiority of a 0/1-hour high-sensitivity cardiac troponin T (hs-cTnT) protocol in compariso …
State-of-the-art diagnosis of myocardial infarction.
Vafaie M. Vafaie M. Diagnosis (Berl). 2016 Dec 1;3(4):137-142. doi: 10.1515/dx-2016-0024. Diagnosis (Berl). 2016. PMID: 29536900 Free article. Review.
The current version of the Universal Definition of Myocardial Infarction (MI) was published in 2012. An acute myocardial infarction (AMI) is characterized by evidence of myocardial necrosis in a clinical setting of acute myocardial ischemia. ...Compared to pr …
The current version of the Universal Definition of Myocardial Infarction (MI) was published in 2012. An acute myocardial infarction ( …
Novel high-sensitivity cardiac troponin I assay in patients with suspected acute coronary syndrome.
Chapman AR, Fujisawa T, Lee KK, Andrews JP, Anand A, Sandeman D, Ferry AV, Stewart S, Marshall L, Strachan FE, Gray A, Newby DE, Shah ASV, Mills NL. Chapman AR, et al. Heart. 2019 Apr;105(8):616-622. doi: 10.1136/heartjnl-2018-314093. Epub 2018 Nov 15. Heart. 2019. PMID: 30442743 Free PMC article. Clinical Trial.
BACKGROUND: High-sensitivity cardiac troponin assays enable the early risk stratification of patients with suspected acute coronary syndrome to identify those at low risk of myocardial infarction or cardiac death. We evaluated the performance of a nove …
BACKGROUND: High-sensitivity cardiac troponin assays enable the early risk stratification of patients with suspected acute …
The Biomarkers for Acute Myocardial Infarction and Heart Failure.
Wang XY, Zhang F, Zhang C, Zheng LR, Yang J. Wang XY, et al. Biomed Res Int. 2020 Jan 17;2020:2018035. doi: 10.1155/2020/2018035. eCollection 2020. Biomed Res Int. 2020. PMID: 32016113 Free PMC article. Review.
There is a broad consensus that cardiac troponin and natriuretic peptides are the preferred biomarkers in clinical practice for the diagnosis of the acute coronary syndrome and heart failure, respectively, while the roles and possible clinical a …
There is a broad consensus that cardiac troponin and natriuretic peptides are the preferred biomarkers in clinical practice fo …
High-sensitivity troponin in the evaluation of patients with suspected acute coronary syndrome: a stepped-wedge, cluster-randomised controlled trial.
Shah ASV, Anand A, Strachan FE, Ferry AV, Lee KK, Chapman AR, Sandeman D, Stables CL, Adamson PD, Andrews JPM, Anwar MS, Hung J, Moss AJ, O'Brien R, Berry C, Findlay I, Walker S, Cruickshank A, Reid A, Gray A, Collinson PO, Apple FS, McAllister DA, Maguire D, Fox KAA, Newby DE, Tuck C, Harkess R, Parker RA, Keerie C, Weir CJ, Mills NL; High-STEACS Investigators. Shah ASV, et al. Lancet. 2018 Sep 15;392(10151):919-928. doi: 10.1016/S0140-6736(18)31923-8. Epub 2018 Aug 28. Lancet. 2018. PMID: 30170853 Free PMC article. Clinical Trial.
We aimed to determine whether the introduction of a high-sensitivity cardiac troponin I (hs-cTnI) assay with a sex-specific 99th centile diagnostic threshold would reduce subsequent myocardial infarction or cardiovascular death in patients with suspected acute co …
We aimed to determine whether the introduction of a high-sensitivity cardiac troponin I (hs-cTnI) assay with a sex-specific 99th cent …
High-Sensitivity Cardiac Troponin I and Clinical Risk Scores in Patients With Suspected Acute Coronary Syndrome.
Chapman AR, Hesse K, Andrews J, Lee KK, Anand A, Shah ASV, Sandeman D, Ferry AV, Jameson J, Piya S, Stewart S, Marshall L, Strachan FE, Gray A, Newby DE, Mills NL. Chapman AR, et al. Circulation. 2018 Oct 16;138(16):1654-1665. doi: 10.1161/CIRCULATIONAHA.118.036426. Circulation. 2018. PMID: 30354460 Free PMC article.
We aimed to determine whether the addition of clinical risk scores would improve the safety of early rule-out pathways for myocardial infarction. METHODS: In 1935 patients with suspected acute coronary syndrome, we evaluated the safety and efficacy of 2 rule- …
We aimed to determine whether the addition of clinical risk scores would improve the safety of early rule-out pathways for myocardial infarc …
High-Sensitivity Troponin and the Application of Risk Stratification Thresholds in Patients With Suspected Acute Coronary Syndrome.
Bularga A, Lee KK, Stewart S, Ferry AV, Chapman AR, Marshall L, Strachan FE, Cruickshank A, Maguire D, Berry C, Findlay I, Shah ASV, Newby DE, Mills NL, Anand A. Bularga A, et al. Circulation. 2019 Nov 5;140(19):1557-1568. doi: 10.1161/CIRCULATIONAHA.119.042866. Epub 2019 Sep 1. Circulation. 2019. PMID: 31475856 Free PMC article.
We evaluate the safety and effectiveness of risk stratification thresholds in patients with suspected acute coronary syndrome. METHODS: Consecutive patients with suspected acute coronary syndrome (n=48 282) were enrolled in a multicenter …
We evaluate the safety and effectiveness of risk stratification thresholds in patients with suspected acute coronary syndro …
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