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Estimation of sucrose esters (E473) in foods using gas chromatography-mass spectrometry.
Scotter MJ, Castle L, Roberts DP. Scotter MJ, et al. Food Addit Contam. 2006 Jun;23(6):539-46. doi: 10.1080/02652030600631877. Food Addit Contam. 2006. PMID: 16766452
A method was developed for estimating the content in foods of the emulsifying additive E473, sucrose esters of fatty acids. The analytical approach taken to estimate the complex mixtures that comprise this additive involved, selective solvent extraction of th …
A method was developed for estimating the content in foods of the emulsifying additive E473, sucrose esters of fatty acids. Th …
Diabetic cardiomyopathy: role of the E3 ubiquitin ligase.
Bai T, Wang F, Mellen N, Zheng Y, Cai L. Bai T, et al. Am J Physiol Endocrinol Metab. 2016 Apr 1;310(7):E473-83. doi: 10.1152/ajpendo.00467.2015. Epub 2016 Jan 5. Am J Physiol Endocrinol Metab. 2016. PMID: 26732687 Free article. Review.
They also modulate the activity of several transcription factors involved in the pathogenesis of DCM. In addition, the E3s degrade both insulin receptor and insulin receptor substrates and also regulate insulin gene transcription, leading to insulin resistance and insulin …
They also modulate the activity of several transcription factors involved in the pathogenesis of DCM. In addition, the E3s degrade bo …
Effects of targeting the VEGF and PDGF pathways in diffuse orthotopic glioma models.
Navis AC, Hamans BC, Claes A, Heerschap A, Jeuken JW, Wesseling P, Leenders WP. Navis AC, et al. J Pathol. 2011 Apr;223(5):626-34. doi: 10.1002/path.2836. Epub 2011 Feb 21. J Pathol. 2011. PMID: 21341272
Therefore, we tested whether combined inhibition of VEGFR and PDGFRbeta increases therapeutic benefit in the orthotopic glioma xenograft models E98 and E473, both displaying the diffuse infiltrative growth that is characteristically observed in most human gliomas. ...These …
Therefore, we tested whether combined inhibition of VEGFR and PDGFRbeta increases therapeutic benefit in the orthotopic glioma xenograft mod …
Identification of the general acid/base catalyst of a family 3 beta-glucosidase from Flavobacterium meningosepticum.
Li YK, Chir J, Tanaka S, Chen FY. Li YK, et al. Biochemistry. 2002 Feb 26;41(8):2751-9. doi: 10.1021/bi016049e. Biochemistry. 2002. PMID: 11851422
On the basis of amino acid sequence alignment of 15 family 3 enzymes, 11 residues (D71, R129, E132, E136, D137, K168, H169, E177, D247, D458, and E473) are highly conserved. All of these residues are studied by site-directed mutagenesis and kinetic investigation. ...All of …
On the basis of amino acid sequence alignment of 15 family 3 enzymes, 11 residues (D71, R129, E132, E136, D137, K168, H169, E177, D247, D458 …
COP1 mutation causes low leaf temperature under various abiotic stresses in Arabidopsis thaliana.
Kim JY, Lee SJ, Min WK, Cha S, Song JT, Seo HS. Kim JY, et al. Plant Direct. 2022 Dec 19;6(12):e473. doi: 10.1002/pld3.473. eCollection 2022 Dec. Plant Direct. 2022. PMID: 36545005 Free PMC article.
Expression of the genes encoding ABA receptors, ABA biosynthesis proteins, positive regulators of stomatal closure and heat tolerance, and ABA-responsive proteins was lower in cop1 mutants that that in WT. In addition, expression of respiration-related genes was lower in c …
Expression of the genes encoding ABA receptors, ABA biosynthesis proteins, positive regulators of stomatal closure and heat tolerance, and A …
Source and fate of circulating citrulline.
Windmueller HG, Spaeth AE. Windmueller HG, et al. Am J Physiol. 1981 Dec;241(6):E473-80. doi: 10.1152/ajpendo.1981.241.6.E473. Am J Physiol. 1981. PMID: 7325229
Acute experiments in which the intestine, intestine plus liver, or kidneys were excluded from the circulation indicate that additional organs may also participate in citrulline exchange, at least when the circulating citrulline level is abnormal. ...
Acute experiments in which the intestine, intestine plus liver, or kidneys were excluded from the circulation indicate that additional …
Use of Lean Healthcare to Improve Hospital Throughput and Reduce LOS.
Mangum CD, Andam-Mejia RL, Hale LR, Mananquil A, Fulcher KR, Hall JL, McDonald LAC, Sjogren KN, Villalon FD, Mehta A, Shomaker K, Johnson EA, Godambe SA. Mangum CD, et al. Pediatr Qual Saf. 2021 Sep 24;6(5):e473. doi: 10.1097/pq9.0000000000000473. eCollection 2021 Sep-Oct. Pediatr Qual Saf. 2021. PMID: 34589647 Free PMC article.
The team developed a daily dashboard that detailed the process and outcome measures to create situational awareness and daily visual management. Additional observations of staff workflow uncovered excessive walking for printer use. Printers were placed at the point of use …
The team developed a daily dashboard that detailed the process and outcome measures to create situational awareness and daily visual managem …
Multiparametric Monitoring of Early Pathophysiological Changes in a Porcine Model of Sequential Focal and Global Cerebral Ischemia.
Mader MM, Heimann A, Kempski O, Wöbker G, Alessandri B. Mader MM, et al. World Neurosurg. 2022 May;161:e473-e481. doi: 10.1016/j.wneu.2022.02.039. Epub 2022 Feb 19. World Neurosurg. 2022. PMID: 35189416
Insufficient reduction (i.e., <50% in both ptiO(2) and CBF) was followed by additional bilateral CCAO. Neurodegenerative changes were detected by Fluoro-Jade B (FJB) staining. RESULTS: Only 1 of 8 animals demonstrated a decrease of >50% in both ptiO(2) and CBF after …
Insufficient reduction (i.e., <50% in both ptiO(2) and CBF) was followed by additional bilateral CCAO. Neurodegenerative changes w …
Study Design and Rationale for the PACE-LUNG Trial: A Multicenter, Single-Arm, Phase II Clinical Trial Evaluating the Efficacy of Additional Chemotherapy for Patients with EGFRm NSCLC with the Continued Presence of Plasma ctDNA EGFRm at Week 3 After Start of Osimertinib First-Line Treatment.
Acker F, Aguinarte L, Althoff F, Heinzen S, Rost M, Wild P, Reiser L, Mänz M, Meyer F, Stratmann J, Sebastian M. Acker F, et al. Clin Lung Cancer. 2022 Nov;23(7):e473-e477. doi: 10.1016/j.cllc.2022.07.019. Epub 2022 Aug 10. Clin Lung Cancer. 2022. PMID: 36089483
Patients with stage IIIB or IV NSCLC and exon 19 deletion or p.L858R EGFR mutation not amenable to curative treatment with persisting ctDNA after 3 to 4 weeks of first-line osimertinib monotherapy will receive additional chemotherapy (4 cycles of either cisplatin/pemetrexe …
Patients with stage IIIB or IV NSCLC and exon 19 deletion or p.L858R EGFR mutation not amenable to curative treatment with persisting ctDNA …
Baseline characteristics, chromosomal alterations, and treatment affecting prognosis of deletion 17p in newly diagnosed myeloma.
Merz M, Hielscher T, Seckinger A, Hose D, Mai EK, Raab MS, Goldschmidt H, Jauch A, Hillengass J. Merz M, et al. Am J Hematol. 2016 Nov;91(11):E473-E477. doi: 10.1002/ajh.24533. Epub 2016 Sep 3. Am J Hematol. 2016. PMID: 27508939 Free article.
Patients with subclonal (10-60% of plasma cells) del(17p) had longer progression-free survival (PFS) than patients with del(17p) in >60% of plasma cells (26 vs. 19 months, P = 0.03). Additional gain of 1q21 was associated with shorter PFS (17 vs. 25 months, P = 0.01). H …
Patients with subclonal (10-60% of plasma cells) del(17p) had longer progression-free survival (PFS) than patients with del(17p) in >60% …
24 results