Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 1
2009 2
2012 1
2013 2
2014 4
2015 5
2016 4
2018 4
2019 4
2020 9
2021 10
2022 4
2023 2
2024 2
2025 2

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

49 results

Results by year

Filters applied: . Clear all
Page 1
Size effect and mucus role on the intestinal toxicity of the E551 food additive and engineered silica nanoparticles.
Zaiter T, Cornu R, Millot N, Herbst M, Pellequer Y, Moarbess G, Martin H, Diab-Assaf M, Béduneau A. Zaiter T, et al. Nanotoxicology. 2022 Mar;16(2):165-182. doi: 10.1080/17435390.2022.2063084. Epub 2022 May 17. Nanotoxicology. 2022. PMID: 35579945
Digestion did not affect the physicochemical properties of the additive. Due to a mean hydrodynamic diameter close to 200 nm, both native and digested E551 additives did not induce any toxic effect in intestinal barrier models. This study emphasized a cutoff …
Digestion did not affect the physicochemical properties of the additive. Due to a mean hydrodynamic diameter close to 200 nm, both na …
Toxicity to RAW264.7 Macrophages of Silica Nanoparticles and the E551 Food Additive, in Combination with Genotoxic Agents.
Dussert F, Arthaud PA, Arnal ME, Dalzon B, Torres A, Douki T, Herlin N, Rabilloud T, Carriere M. Dussert F, et al. Nanomaterials (Basel). 2020 Jul 21;10(7):1418. doi: 10.3390/nano10071418. Nanomaterials (Basel). 2020. PMID: 32708108 Free PMC article.
In this study, we assessed the toxicity towards macrophages and intestinal epithelial cells of three SAS particles, either isolated SiO(2) nanoparticles (LS30) or SiO(2) particles composed of agglomerated-aggregates of fused primary particles, either food-grade (E551) or n …
In this study, we assessed the toxicity towards macrophages and intestinal epithelial cells of three SAS particles, either isolated SiO(2) n …
Novel insights into the risk assessment of the nanomaterial synthetic amorphous silica, additive E551, in food.
van Kesteren PC, Cubadda F, Bouwmeester H, van Eijkeren JC, Dekkers S, de Jong WH, Oomen AG. van Kesteren PC, et al. Nanotoxicology. 2015 May;9(4):442-52. doi: 10.3109/17435390.2014.940408. Epub 2014 Jul 18. Nanotoxicology. 2015. PMID: 25033893
Depending on the production process, SAS exists in four main forms, and each form comprises various types with different physicochemical characteristics. SAS is widely used in foods as additive E551. The novel insights from other studies relate to low gastrointestin …
Depending on the production process, SAS exists in four main forms, and each form comprises various types with different physicochemical cha …
Co-exposure to commercial food product ingredient E341 and E551 triggers cytotoxicity in human mesenchymal stem cells.
Athinarayanan J, Khaibary AAL, Periasamy VS, Alatiah KA, Shamlan G, Alsawmahi ON, Alshatwi AA. Athinarayanan J, et al. Environ Sci Pollut Res Int. 2023 Mar;30(12):33264-33274. doi: 10.1007/s11356-022-24497-1. Epub 2022 Dec 7. Environ Sci Pollut Res Int. 2023. PMID: 36474033
Still, nanoscale ingredients from food products are not explored well, and only a few have attended to the possible effects of food additive-based nanoparticles in food. The physicochemical properties of food additives and their fate on human health are still unknow …
Still, nanoscale ingredients from food products are not explored well, and only a few have attended to the possible effects of food addit …
Presence of nanosilica (E551) in commercial food products: TNF-mediated oxidative stress and altered cell cycle progression in human lung fibroblast cells.
Athinarayanan J, Periasamy VS, Alsaif MA, Al-Warthan AA, Alshatwi AA. Athinarayanan J, et al. Cell Biol Toxicol. 2014 Apr;30(2):89-100. doi: 10.1007/s10565-014-9271-8. Epub 2014 Feb 14. Cell Biol Toxicol. 2014. PMID: 24526451
Silica (E551) is commonly used as an anti-caking agent in food products. The morphology and the dimension of the added silica particles are not, however, usually stated on the food product label. ...The results suggest that E551 induces a dose-dependent cytotoxicity …
Silica (E551) is commonly used as an anti-caking agent in food products. The morphology and the dimension of the added silica particl …
Evidence-based Recommendations for Pediatric Orthopaedic Practice.
Mulpuri K, Schaeffer EK, Sanders J, Zaltz I, Kocher MS. Mulpuri K, et al. J Pediatr Orthop. 2018 Oct;38(9):e551-e555. doi: 10.1097/BPO.0000000000001230. J Pediatr Orthop. 2018. PMID: 30074590 Review.
SIGNIFICANCE: Despite a positive result demonstrating an effect of botulinum toxin treatment on spastic equinus in CP, the long-term functional impact and optimal dose remains to be determined. In addition, the negative result in the second study demonstrates the need for …
SIGNIFICANCE: Despite a positive result demonstrating an effect of botulinum toxin treatment on spastic equinus in CP, the long-term functio …
Short-term biodistribution and clearance of intravenously administered silica nanoparticles.
Waegeneers N, Brasseur A, Van Doren E, Van der Heyden S, Serreyn PJ, Pussemier L, Mast J, Schneider YJ, Ruttens A, Roels S. Waegeneers N, et al. Toxicol Rep. 2018 May 23;5:632-638. doi: 10.1016/j.toxrep.2018.05.004. eCollection 2018. Toxicol Rep. 2018. PMID: 30622900 Free PMC article.
Recently, concerns have been raised about potential adverse effects of synthetic amorphous silica, commonly used as food additive (E551), since silica nanoparticles have been detected in food containing E551. ...In treated animals the liver showed in addit …
Recently, concerns have been raised about potential adverse effects of synthetic amorphous silica, commonly used as food additive ( …
Inorganic food additive nanomaterials alter the allergenicity of milk proteins.
Phue WH, Xu K, George S. Phue WH, et al. Food Chem Toxicol. 2022 Apr;162:112874. doi: 10.1016/j.fct.2022.112874. Epub 2022 Feb 17. Food Chem Toxicol. 2022. PMID: 35183651
This study analyzed the effect of widely used food additive nanomaterials (silica and titania) on the antigenicity and allergenicity of milk proteins (beta-lactoglobulin and casein) and skimmed milk. ...
This study analyzed the effect of widely used food additive nanomaterials (silica and titania) on the antigenicity and allergenicity …
Co-exposure to boscalid and TiO(2) (E171) or SiO(2) (E551) downregulates cell junction gene expression in small intestinal epithelium cellular model and increases pesticide translocation.
Cao X, Khare S, DeLoid GM, Gokulan K, Demokritou P. Cao X, et al. NanoImpact. 2021 Apr;22:100306. doi: 10.1016/j.impact.2021.100306. Epub 2021 Mar 10. NanoImpact. 2021. PMID: 33869896 Free PMC article.
A recent published study showed that TiO(2) (E171) and SiO(2) (E551), two widely used nano-enabled food additives, increased the translocation of the commonly used pesticide boscalid by 20% and 30% respectively. ...This novel finding raises health safety concerns fo …
A recent published study showed that TiO(2) (E171) and SiO(2) (E551), two widely used nano-enabled food additives, increased t …
Co-exposure to boscalid and TiO(2) (E171) or SiO(2) (E551) downregulates cell junction gene expression in small intestinal epithelium cellular model and increases pesticide translocation.
Cao X, Khare S, DeLoid GM, Gokulan K, Demokritou P. Cao X, et al. NanoImpact. 2021 Apr;22:100306. doi: 10.1016/j.impact.2021.100306. Epub 2021 Mar 10. NanoImpact. 2021. PMID: 35559963
A recent published study showed that TiO(2) (E171) and SiO(2) (E551), two widely used nano-enabled food additives, increased the translocation of the commonly used pesticide boscalid by 20% and 30% respectively. ...This novel finding raises health safety concerns fo …
A recent published study showed that TiO(2) (E171) and SiO(2) (E551), two widely used nano-enabled food additives, increased t …
49 results