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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1984 4
1985 1
1987 4
1989 4
1990 4
1991 1
1992 3
1993 2
1994 4
1995 2
1996 2
1997 1
1998 3
1999 1
2000 3
2001 1
2002 7
2003 2
2004 4
2005 4
2006 4
2008 2
2009 5
2010 10
2011 9
2012 7
2013 9
2014 10
2015 10
2016 7
2017 1
2018 3
2019 6
2020 9
2021 5
2022 3
2023 1
2024 2
2025 4
2026 1

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152 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Pharmacokinetics and food impact assessment of ademetionine enteric-coated tablet as an endogenous substance drug in healthy Chinese volunteers.
Zhang J, Liu H, Tang L, Lin H, Yao Y, Tong Y, Jin M, Wang K. Zhang J, et al. J Clin Pharm Ther. 2022 Jun;47(6):738-744. doi: 10.1111/jcpt.13601. Epub 2022 Jan 3. J Clin Pharm Ther. 2022. PMID: 34981547 Clinical Trial.
WHAT IS KNOWN AND OBJECTIVES: Ademetionine 1,4-Butanedisulfonate (SAMe) enteric-coated tablets are widely used for treatment of pre-cirrhotic and cirrhotic intrahepatic cholestasis, as well as intrahepatic cholestasis of pregnancy (ICP), but incomplete clinical data and in …
WHAT IS KNOWN AND OBJECTIVES: Ademetionine 1,4-Butanedisulfonate (SAMe) enteric-coated tablets are widely used for treatment of pre-c …
Efficacy of Pharmacological Interventions in Milder Depression: A Systematic Review and Meta-Analysis.
Urata M, Sakurai H, Ueno F, Maruki T, Tada T, Uchida T, Matsumoto Y, Murao M, Tomita M, Baba H, Kato M, Tsuboi T, Watanabe K. Urata M, et al. Neuropsychopharmacol Rep. 2025 Mar;45(1):e70008. doi: 10.1002/npr2.70008. Neuropsychopharmacol Rep. 2025. PMID: 40014460 Free PMC article.
Other interventions, such as lavender, lemon balm, and transcranial electroacupuncture stimulation, were as effective as antidepressants. Conversely, S-adenosylmethionine did not produce significant improvements relative to placebo. CONCLUSION: This review demonstra …
Other interventions, such as lavender, lemon balm, and transcranial electroacupuncture stimulation, were as effective as antidepressants. Co …
Pharmacological interventions for treating intrahepatic cholestasis of pregnancy.
Walker KF, Chappell LC, Hague WM, Middleton P, Thornton JG. Walker KF, et al. Cochrane Database Syst Rev. 2020 Jul 27;7(7):CD000493. doi: 10.1002/14651858.CD000493.pub3. Cochrane Database Syst Rev. 2020. PMID: 32716060 Free PMC article.
The ten different pharmacological interventions were: agents believed to detoxify bile acids (UCDA) and S-adenosylmethionine (SAMe); agents used to bind bile acids in the intestine (activated charcoal, guar gum, cholestyramine); Chinese herbal medicines (yinchenghao …
The ten different pharmacological interventions were: agents believed to detoxify bile acids (UCDA) and S-adenosylmethionine ( …
Metabolic Signature of Arsenic Exposure and Metabolism: The Folic Acid and Creatine Trial.
Li W, Wu H, Goldsmith J, Glabonjat RA, Ilievski V, Balac O, Slavkovich V, Pinto-Pacheco B, Lin X, Parvez F, Jackson GL, Siddique AB, Uddin MN, Islam T, Martinez-Morata I, Navas-Acien A, Niedzwiecki MM, Kioumourtzoglou MA, Pierce BL, Graziano JH, Bottiglieri T, Walker DI, Gamble MV. Li W, et al. Environ Sci Technol. 2025 Jul 29;59(29):14905-14916. doi: 10.1021/acs.est.5c01597. Epub 2025 Jul 16. Environ Sci Technol. 2025. PMID: 40668877 Free PMC article. Clinical Trial.
Of 11 measured OCM metabolites, cystathionine was positively associated with all bAs species. Methionine, S-adenosylmethionine, S-adenosylhomocysteine, cysteine, choline, betaine, and dimethylglycine were associated with increased As methylation profiles in u …
Of 11 measured OCM metabolites, cystathionine was positively associated with all bAs species. Methionine, S-adenosylmethionine …
[A trial of ademetionine in the treatment of intrahepatic biliary stasis viral hepatitis].
Qin B, Guo S, Zhao Y, Zou S, Zhang Q, Wang Z, Zeng W, Zhang D. Qin B, et al. Zhonghua Gan Zang Bing Za Zhi. 2000 Jun;8(3):158-60. Zhonghua Gan Zang Bing Za Zhi. 2000. PMID: 10880165 Clinical Trial. Chinese.
OBJECTIVE: To observe the efficacy and safety of ademetionine in the treatment of viral hepatitis with intrahepatic biliary stasis. METHODS: In this series, 110 patients with viral hepatitis associated intrahepatic biliary stasis were randomly divided into Groups A and B. …
OBJECTIVE: To observe the efficacy and safety of ademetionine in the treatment of viral hepatitis with intrahepatic biliary stasis. M …
SAMe and sexual functioning.
Dording CM, Mischoulon D, Shyu I, Alpert JE, Papakostas GI. Dording CM, et al. Eur Psychiatry. 2012 Aug;27(6):451-4. doi: 10.1016/j.eurpsy.2011.01.003. Epub 2011 Mar 12. Eur Psychiatry. 2012. PMID: 21398094 Clinical Trial.
152 results