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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1952 1
1963 1
1966 1
1967 4
1968 2
1970 2
1971 4
1972 6
1974 2
1975 17
1976 11
1977 20
1978 11
1979 13
1980 17
1981 16
1982 15
1983 20
1984 25
1985 8
1986 20
1987 14
1988 30
1989 18
1990 27
1991 20
1992 31
1993 21
1994 48
1995 44
1996 62
1997 113
1998 88
1999 117
2000 145
2001 138
2002 175
2003 187
2004 204
2005 249
2006 262
2007 313
2008 316
2009 319
2010 323
2011 438
2012 475
2013 514
2014 537
2015 604
2016 629
2017 785
2018 818
2019 1002
2020 1177
2021 1432
2022 103
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10,694 results
Results by year
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Page 1
Adeno-associated virus (AAV) vectors in cancer gene therapy.
Santiago-Ortiz JL, Schaffer DV. Santiago-Ortiz JL, et al. J Control Release. 2016 Oct 28;240:287-301. doi: 10.1016/j.jconrel.2016.01.001. Epub 2016 Jan 12. J Control Release. 2016. PMID: 26796040 Free PMC article. Review.
Gene delivery vectors based on adeno-associated virus (AAV) have been utilized in a large number of gene therapy clinical trials, which have demonstrated their strong safety profile and increasingly their therapeutic efficacy for treating monogenic dis …
Gene delivery vectors based on adeno-associated virus (AAV) have been utilized in a large number of gene therapy …
Emerging Issues in AAV-Mediated In Vivo Gene Therapy.
Colella P, Ronzitti G, Mingozzi F. Colella P, et al. Mol Ther Methods Clin Dev. 2017 Dec 1;8:87-104. doi: 10.1016/j.omtm.2017.11.007. eCollection 2018 Mar 16. Mol Ther Methods Clin Dev. 2017. PMID: 29326962 Free PMC article. Review.
In recent years, the number of clinical trials in which adeno-associated virus (AAV) vectors have been used for in vivo gene transfer has steadily increased. ...In this review, we will give an overview on the biology of AAV vector, discuss the d …
In recent years, the number of clinical trials in which adeno-associated virus (AAV) vectors have been used for …
Adeno-associated virus serotypes: vector toolkit for human gene therapy.
Wu Z, Asokan A, Samulski RJ. Wu Z, et al. Mol Ther. 2006 Sep;14(3):316-27. doi: 10.1016/j.ymthe.2006.05.009. Epub 2006 Jul 7. Mol Ther. 2006. PMID: 16824801 Free article. Review.
Recombinant adeno-associated viral (AAV) vectors have rapidly advanced to the forefront of gene therapy in the past decade. ...Strategies for engineering hybrid AAV vectors derived from AAV serotypes and potential implications of the rapidly exp …
Recombinant adeno-associated viral (AAV) vectors have rapidly advanced to the forefront of gene therapy in the past dec …
The role of infection in miscarriage.
Giakoumelou S, Wheelhouse N, Cuschieri K, Entrican G, Howie SE, Horne AW. Giakoumelou S, et al. Hum Reprod Update. 2016 Jan-Feb;22(1):116-33. doi: 10.1093/humupd/dmv041. Epub 2015 Sep 19. Hum Reprod Update. 2016. PMID: 26386469 Free PMC article. Review.
Q fever, adeno-associated virus, Bocavirus, Hepatitis C and Mycoplasma genitalium infections do not appear to affect pregnancy outcome. The effects of Chlamydia trachomatis, Toxoplasma gondii, human papillomavirus, herpes simplex virus, parvo
Q fever, adeno-associated virus, Bocavirus, Hepatitis C and Mycoplasma genitalium infections do not appear to af …
Crossing the blood-brain barrier with AAV vectors.
Liu D, Zhu M, Zhang Y, Diao Y. Liu D, et al. Metab Brain Dis. 2021 Jan;36(1):45-52. doi: 10.1007/s11011-020-00630-2. Epub 2020 Nov 17. Metab Brain Dis. 2021. PMID: 33201426 Review.
Central nervous system (CNS) diseases are some of the most difficult to treat because the blood-brain barrier (BBB) almost entirely limits the passage of many therapeutic drugs into the CNS. Gene therapy based on the adeno-associated virus (AAV) vector …
Central nervous system (CNS) diseases are some of the most difficult to treat because the blood-brain barrier (BBB) almost entirely limits t …
Adeno-associated Virus (AAV) Dual Vector Strategies for Gene Therapy Encoding Large Transgenes.
McClements ME, MacLaren RE. McClements ME, et al. Yale J Biol Med. 2017 Dec 19;90(4):611-623. eCollection 2017 Dec. Yale J Biol Med. 2017. PMID: 29259525 Free PMC article. Review.
The use of adeno-associated viral (AAV) vectors for gene therapy treatments of inherited disorders has accelerated over the past decade with multiple clinical trials ongoing in varying tissue types and new ones initiating every year. ...Given that numerous di …
The use of adeno-associated viral (AAV) vectors for gene therapy treatments of inherited disorders has accelerated over …
Adeno-associated Virus (AAV) Capsid Chimeras with Enhanced Infectivity Reveal a Core Element in the AAV Genome Critical for both Cell Transduction and Capsid Assembly.
Viney L, Bürckstümmer T, Eddington C, Mietzsch M, Choudhry M, Henley T, Agbandje-McKenna M. Viney L, et al. J Virol. 2021 Jan 13;95(7):e02023-20. doi: 10.1128/JVI.02023-20. Online ahead of print. J Virol. 2021. PMID: 33441336 Free PMC article.
Adeno-associated viruses (AAV) have attracted significant attention in the field of gene and cell therapy due to highly effective delivery of therapeutic genes into human cells. ...Furthermore, we demonstrate a novel finding, and an important consideration fo
Adeno-associated viruses (AAV) have attracted significant attention in the field of gene and cell therapy due to highly
AAV: An Overview of Unanswered Questions.
Berns KI, Muzyczka N. Berns KI, et al. Hum Gene Ther. 2017 Apr;28(4):308-313. doi: 10.1089/hum.2017.048. Hum Gene Ther. 2017. PMID: 28335618 Free PMC article. Review.
AAV has been studied for 55 years and has been developed as a vector for about 35 years. By now, there is a fairly good idea of the dimensions of what would be useful to know to employ AAV optimally as a vector, but there are still many unanswered questions within t
AAV has been studied for 55 years and has been developed as a vector for about 35 years. By now, there is a fairly good idea of the d
CNS Transduction Benefits of AAV-PHP.eB over AAV9 Are Dependent on Administration Route and Mouse Strain.
Mathiesen SN, Lock JL, Schoderboeck L, Abraham WC, Hughes SM. Mathiesen SN, et al. Mol Ther Methods Clin Dev. 2020 Oct 20;19:447-458. doi: 10.1016/j.omtm.2020.10.011. eCollection 2020 Dec 11. Mol Ther Methods Clin Dev. 2020. PMID: 33294493 Free PMC article.
Adeno-associated viral (AAV) vectors are attractive tools for central nervous system (CNS) gene therapy because some vectors can cross the blood-brain barrier (BBB), allowing them to be used as minimally invasive treatments. A novel AAV vector recently
Adeno-associated viral (AAV) vectors are attractive tools for central nervous system (CNS) gene therapy because some ve
Adeno-associated virus (AAV) capsid engineering in liver-directed gene therapy.
Rodríguez-Márquez E, Meumann N, Büning H. Rodríguez-Márquez E, et al. Expert Opin Biol Ther. 2021 Jun;21(6):749-766. doi: 10.1080/14712598.2021.1865303. Epub 2020 Dec 30. Expert Opin Biol Ther. 2021. PMID: 33331201
Introduction: Gene therapy clinical trials with adeno-associated virus (AAV) vectors report impressive clinical efficacy data. ...Capsid engineering is also expected to result in AAV vectors applicable to patients with preexisting immunity towar …
Introduction: Gene therapy clinical trials with adeno-associated virus (AAV) vectors report impressive clinical …
10,694 results
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