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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1970 2
1971 1
1975 1
1977 3
1978 3
1979 1
1982 1
1983 2
1984 5
1985 3
1986 4
1987 4
1988 6
1989 6
1990 7
1991 4
1992 5
1993 7
1994 11
1995 15
1996 12
1997 12
1998 15
1999 24
2000 23
2001 35
2002 45
2003 51
2004 68
2005 103
2006 128
2007 154
2008 151
2009 176
2010 246
2011 258
2012 280
2013 343
2014 399
2015 416
2016 446
2017 478
2018 549
2019 626
2020 777
2021 908
2022 911
2023 1016
2024 1141
2025 358

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9,059 results

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Page 1
DNA damage and repair in age-related inflammation.
Zhao Y, Simon M, Seluanov A, Gorbunova V. Zhao Y, et al. Nat Rev Immunol. 2023 Feb;23(2):75-89. doi: 10.1038/s41577-022-00751-y. Epub 2022 Jul 13. Nat Rev Immunol. 2023. PMID: 35831609 Free PMC article. Review.
However, emerging evidence shows that inflammation is another major consequence of DNA damage. Inflammation is a hallmark of ageing and the driver of multiple age-related diseases. ...We also discuss how epigenetic changes triggered by DNA damage can l …
However, emerging evidence shows that inflammation is another major consequence of DNA damage. Inflammation is a hallmark of a …
Age and Age-Related Diseases: Role of Inflammation Triggers and Cytokines.
Rea IM, Gibson DS, McGilligan V, McNerlan SE, Alexander HD, Ross OA. Rea IM, et al. Front Immunol. 2018 Apr 9;9:586. doi: 10.3389/fimmu.2018.00586. eCollection 2018. Front Immunol. 2018. PMID: 29686666 Free PMC article. Review.
Despite research there is no clear understanding about the causes of "inflamm-aging" that underpin most major age-related diseases, including atherosclerosis, diabetes, Alzheimer's disease, rheumatoid arthritis, cancer, and aging itself. ...The age-related …
Despite research there is no clear understanding about the causes of "inflamm-aging" that underpin most major age-related dise …
Inflammaging: a new immune-metabolic viewpoint for age-related diseases.
Franceschi C, Garagnani P, Parini P, Giuliani C, Santoro A. Franceschi C, et al. Nat Rev Endocrinol. 2018 Oct;14(10):576-590. doi: 10.1038/s41574-018-0059-4. Nat Rev Endocrinol. 2018. PMID: 30046148 Review.
Ageing and age-related diseases share some basic mechanistic pillars that largely converge on inflammation. During ageing, chronic, sterile, low-grade inflammation - called inflammaging - develops, which contributes to the pathogenesis of age- …
Ageing and age-related diseases share some basic mechanistic pillars that largely converge on inflammation. During agei …
Chronic inflammation and oxidative stress as a major cause of age-related diseases and cancer.
Khansari N, Shakiba Y, Mahmoudi M. Khansari N, et al. Recent Pat Inflamm Allergy Drug Discov. 2009 Jan;3(1):73-80. doi: 10.2174/187221309787158371. Recent Pat Inflamm Allergy Drug Discov. 2009. PMID: 19149749 Review.
Moreover, many studies suggest that chronic inflammation could have serious role in wide variety of age-related diseases including diabetes, cardiovascular and autoimmune diseases. ...In addition, free radicals can lead to mutation and DNA damage that can be …
Moreover, many studies suggest that chronic inflammation could have serious role in wide variety of age-related disease …
Age-related changes in the gut microbiota influence systemic inflammation and stroke outcome.
Spychala MS, Venna VR, Jandzinski M, Doran SJ, Durgan DJ, Ganesh BP, Ajami NJ, Putluri N, Graf J, Bryan RM, McCullough LD. Spychala MS, et al. Ann Neurol. 2018 Jul;84(1):23-36. doi: 10.1002/ana.25250. Epub 2018 Jul 18. Ann Neurol. 2018. PMID: 29733457 Free PMC article.
OBJECTIVE: Chronic systemic inflammation contributes to the pathogenesis of many age-related diseases. Although not well understood, alterations in the gut microbiota, or dysbiosis, may be responsible for age-related inflammation. ...We c …
OBJECTIVE: Chronic systemic inflammation contributes to the pathogenesis of many age-related diseases. Although not wel …
The changing landscape of atherosclerosis.
Libby P. Libby P. Nature. 2021 Apr;592(7855):524-533. doi: 10.1038/s41586-021-03392-8. Epub 2021 Apr 21. Nature. 2021. PMID: 33883728 Review.
Probing the pathogenesis of atherosclerosis has highlighted the role of the bone marrow: somatic mutations in stem cells can cause clonal haematopoiesis, which represents a previously unrecognized but common and potent age-related contributor to the risk of developi …
Probing the pathogenesis of atherosclerosis has highlighted the role of the bone marrow: somatic mutations in stem cells can cause clonal ha …
Age-Related Alterations in Immune Function and Inflammation: Focus on Ischemic Stroke.
Chen Q, Wu M, Tang Q, Yan P, Zhu L. Chen Q, et al. Aging Dis. 2024 May 7;15(3):1046-1074. doi: 10.14336/AD.2023.0721-1. Aging Dis. 2024. PMID: 37728582 Free PMC article. Review.
Preventing brain aging remains a priority public health goal, and integrative and comprehensive aging analyses have revealed that immunosenescence is a potential cause of age-related brain damage and disease (e.g., stroke). Importantly, the neuroinflammatory and imm …
Preventing brain aging remains a priority public health goal, and integrative and comprehensive aging analyses have revealed that immunosene …
Modulation of inflammation and immunity by omega-3 fatty acids: a possible role for prevention and to halt disease progression in autoimmune, viral, and age-related disorders.
Poggioli R, Hirani K, Jogani VG, Ricordi C. Poggioli R, et al. Eur Rev Med Pharmacol Sci. 2023 Aug;27(15):7380-7400. doi: 10.26355/eurrev_202308_33310. Eur Rev Med Pharmacol Sci. 2023. PMID: 37606147 Free article.
Over the last 30 years, however, the Western diet has shifted largely from Omega-3 to Omega-6 consumption. Uncontrolled aberrant and chronic inflammation is a leading component of many common diseases, including arthritis, cardiovascular diseases, neurodegenerative disease …
Over the last 30 years, however, the Western diet has shifted largely from Omega-3 to Omega-6 consumption. Uncontrolled aberrant and chronic …
Inflammation produced by senescent osteocytes mediates age-related bone loss.
Wang Z, Zhang X, Cheng X, Ren T, Xu W, Li J, Wang H, Zhang J. Wang Z, et al. Front Immunol. 2023 Feb 6;14:1114006. doi: 10.3389/fimmu.2023.1114006. eCollection 2023. Front Immunol. 2023. PMID: 36814916 Free PMC article.
PURPOSE: The molecular mechanisms of age-related bone loss are unclear and without valid drugs yet. The aims of this study were to explore the molecular changes that occur in bone tissue during age-related bone loss, to further clarify the changes in f …
PURPOSE: The molecular mechanisms of age-related bone loss are unclear and without valid drugs yet. The aims of this study wer …
The role of nutrition in inflammaging.
Di Giosia P, Stamerra CA, Giorgini P, Jamialahamdi T, Butler AE, Sahebkar A. Di Giosia P, et al. Ageing Res Rev. 2022 May;77:101596. doi: 10.1016/j.arr.2022.101596. Epub 2022 Feb 24. Ageing Res Rev. 2022. PMID: 35219904 Review.
This is believed to substantially contribute to the pathogenesis of many age-related diseases and to the progression of the ageing process. An adequate nutritional status is of great importance for maintaining proper immune system functionality and preventing frailt …
This is believed to substantially contribute to the pathogenesis of many age-related diseases and to the progression of the ag …
9,059 results