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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1925 2
1928 3
1929 1
1930 1
1934 2
1935 2
1936 3
1937 1
1939 1
1940 4
1942 6
1944 2
1945 11
1946 77
1947 80
1948 52
1949 43
1950 66
1951 86
1952 108
1953 212
1954 278
1955 353
1956 397
1957 381
1958 399
1959 423
1960 431
1961 528
1962 589
1963 862
1964 1480
1965 1354
1966 1329
1967 1519
1968 1314
1969 1286
1970 1162
1971 1330
1972 1306
1973 1456
1974 1624
1975 1962
1976 1919
1977 2105
1978 2718
1979 3012
1980 3515
1981 3710
1982 3971
1983 3733
1984 3983
1985 3862
1986 4274
1987 4471
1988 5100
1989 5740
1990 5806
1991 6075
1992 6331
1993 6470
1994 6616
1995 6726
1996 6875
1997 7700
1998 7427
1999 7626
2000 8371
2001 8696
2002 9508
2003 9975
2004 10635
2005 12123
2006 12798
2007 13768
2008 14839
2009 16350
2010 17726
2011 18784
2012 20190
2013 22536
2014 25962
2015 27940
2016 29888
2017 31340
2018 33119
2019 35736
2020 41317
2021 44394
2022 44136
2023 42948
2024 16171

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Search Results

639,717 results

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Page 1
Hallmarks of aging: An expanding universe.
López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. López-Otín C, et al. Cell. 2023 Jan 19;186(2):243-278. doi: 10.1016/j.cell.2022.11.001. Epub 2023 Jan 3. Cell. 2023. PMID: 36599349 Free article. Review.
Aging is driven by hallmarks fulfilling the following three premises: (1) their age-associated manifestation, (2) the acceleration of aging by experimentally accentuating them, and (3) the opportunity to decelerate, stop, or reverse aging by therapeutic inter …
Aging is driven by hallmarks fulfilling the following three premises: (1) their age-associated manifestation, (2) the acceleration of …
Targeting aging mechanisms: pharmacological perspectives.
Moskalev A, Guvatova Z, Lopes IA, Beckett CW, Kennedy BK, De Magalhaes JP, Makarov AA. Moskalev A, et al. Trends Endocrinol Metab. 2022 Apr;33(4):266-280. doi: 10.1016/j.tem.2022.01.007. Epub 2022 Feb 17. Trends Endocrinol Metab. 2022. PMID: 35183431 Review.
Geroprotectors slow down aging and promote healthy longevity in model animals. Although hundreds of compounds have been shown to extend the life of laboratory model organisms, clinical studies on potential geroprotectors are exceedingly rare, especially in healthy elders. …
Geroprotectors slow down aging and promote healthy longevity in model animals. Although hundreds of compounds have been shown to exte …
Biological psychological and social determinants of old age: bio-psycho-social aspects of human aging.
Dziechciaż M, Filip R. Dziechciaż M, et al. Ann Agric Environ Med. 2014;21(4):835-8. doi: 10.5604/12321966.1129943. Ann Agric Environ Med. 2014. PMID: 25528930 Free article. Review.
Psychical ageing refers to human awareness and his adaptability to the ageing process. ...Social ageing refers to how a human being perceives the ageing process and how society sees it....
Psychical ageing refers to human awareness and his adaptability to the ageing process. ...Social ageing refers to how a …
Biomarkers and aging.
Imbert I. Imbert I. Biomark Med. 2014;8(5):621-3. doi: 10.2217/bmm.14.40. Biomark Med. 2014. PMID: 25123029 Free article.
Biomarkers and Ageing 25 February 2014, London, UK This conference was organized by Euroscicon and was part of the 2014 Ageing Summit. ...Presentations as well as the discussion panel session brought opportunities to widely discuss the relevance of biomarkers as sig …
Biomarkers and Ageing 25 February 2014, London, UK This conference was organized by Euroscicon and was part of the 2014 Ageing …
Aging as disease.
De Winter G. De Winter G. Med Health Care Philos. 2015 May;18(2):237-43. doi: 10.1007/s11019-014-9600-y. Med Health Care Philos. 2015. PMID: 25240472
In this paper, I will argue that ageing can be construed as disease. First, the concept of disease is discussed, where the distinction is made between two lines of thought, an objectivist and a subjectivist one. ...In the third section, two potential implications of the vi …
In this paper, I will argue that ageing can be construed as disease. First, the concept of disease is discussed, where the distinctio …
Aging Fits the Disease Criteria of the International Classification of Diseases.
Khaltourina D, Matveyev Y, Alekseev A, Cortese F, Ioviţă A. Khaltourina D, et al. Mech Ageing Dev. 2020 Jul;189:111230. doi: 10.1016/j.mad.2020.111230. Epub 2020 Apr 3. Mech Ageing Dev. 2020. PMID: 32251691 Review.
The disease criteria used by the World Health Organization (WHO) were applied to human biological aging in order to assess whether aging can be classified as a disease. ...We identified a number of clinically proven interventions, as well as genetic and environmenta …
The disease criteria used by the World Health Organization (WHO) were applied to human biological aging in order to assess whether …
Hallmarks of Cellular Senescence.
Hernandez-Segura A, Nehme J, Demaria M. Hernandez-Segura A, et al. Trends Cell Biol. 2018 Jun;28(6):436-453. doi: 10.1016/j.tcb.2018.02.001. Epub 2018 Feb 21. Trends Cell Biol. 2018. PMID: 29477613 Review.
Therefore, the identification, characterization, and pharmacological elimination of senescent cells have gained attention in the field of aging research. However, the nonspecificity of current senescence markers and the existence of different senescence programs strongly l …
Therefore, the identification, characterization, and pharmacological elimination of senescent cells have gained attention in the field of …
From discoveries in ageing research to therapeutics for healthy ageing.
Campisi J, Kapahi P, Lithgow GJ, Melov S, Newman JC, Verdin E. Campisi J, et al. Nature. 2019 Jul;571(7764):183-192. doi: 10.1038/s41586-019-1365-2. Epub 2019 Jul 10. Nature. 2019. PMID: 31292558 Free PMC article. Review.
For several decades, understanding ageing and the processes that limit lifespan have challenged biologists. ...Here we summarize the milestones that mark this scientific triumph, discuss different ageing pathways and processes, and suggest that ageing researc …
For several decades, understanding ageing and the processes that limit lifespan have challenged biologists. ...Here we summarize the …
Telomere dysfunction in ageing and age-related diseases.
Rossiello F, Jurk D, Passos JF, d'Adda di Fagagna F. Rossiello F, et al. Nat Cell Biol. 2022 Feb;24(2):135-147. doi: 10.1038/s41556-022-00842-x. Epub 2022 Feb 14. Nat Cell Biol. 2022. PMID: 35165420 Free PMC article. Review.
Ageing organisms accumulate senescent cells that are thought to contribute to body dysfunction. Telomere shortening and damage are recognized causes of cellular senescence and ageing. Several human conditions associated with normal ageing are precipitated by …
Ageing organisms accumulate senescent cells that are thought to contribute to body dysfunction. Telomere shortening and damage are re …
Ageing as a risk factor for neurodegenerative disease.
Hou Y, Dan X, Babbar M, Wei Y, Hasselbalch SG, Croteau DL, Bohr VA. Hou Y, et al. Nat Rev Neurol. 2019 Oct;15(10):565-581. doi: 10.1038/s41582-019-0244-7. Epub 2019 Sep 9. Nat Rev Neurol. 2019. PMID: 31501588 Review.
Ageing is the primary risk factor for most neurodegenerative diseases, including Alzheimer disease (AD) and Parkinson disease (PD). ...The central biological mechanisms of ageing and their potential as targets of novel therapies for neurodegenerative diseases are al …
Ageing is the primary risk factor for most neurodegenerative diseases, including Alzheimer disease (AD) and Parkinson disease (PD). . …
639,717 results
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