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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1936 1
1957 1
1958 2
1959 1
1960 1
1962 1
1963 1
1964 5
1965 1
1966 2
1967 5
1968 2
1969 5
1970 8
1971 4
1972 6
1973 1
1974 2
1975 11
1976 7
1977 8
1978 9
1979 7
1980 11
1981 9
1982 14
1983 22
1984 15
1985 21
1986 16
1987 16
1988 18
1989 45
1990 36
1991 48
1992 37
1993 46
1994 51
1995 54
1996 82
1997 70
1998 97
1999 84
2000 103
2001 148
2002 173
2003 210
2004 249
2005 364
2006 387
2007 449
2008 503
2009 617
2010 758
2011 808
2012 905
2013 1155
2014 1426
2015 1613
2016 1809
2017 2082
2018 2318
2019 2559
2020 3249
2021 3661
2022 3536
2023 3693
2024 1249

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30,833 results

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Page 1
Single-cell analyses of aging, inflammation and senescence.
Uyar B, Palmer D, Kowald A, Murua Escobar H, Barrantes I, Möller S, Akalin A, Fuellen G. Uyar B, et al. Ageing Res Rev. 2020 Dec;64:101156. doi: 10.1016/j.arr.2020.101156. Epub 2020 Sep 16. Ageing Res Rev. 2020. PMID: 32949770 Free PMC article. Review.
Single-cell gene expression (transcriptomics) data are becoming robust and abundant, and are increasingly used to track organisms along their life-course. This allows investigation into how aging affects cellular transcriptomes, and how changes in transcriptomes may underl …
Single-cell gene expression (transcriptomics) data are becoming robust and abundant, and are increasingly used to track organisms along thei …
Connecting aging biology and inflammation in the omics era.
Walker KA, Basisty N, Wilson DM 3rd, Ferrucci L. Walker KA, et al. J Clin Invest. 2022 Jul 15;132(14):e158448. doi: 10.1172/JCI158448. J Clin Invest. 2022. PMID: 35838044 Free PMC article. Review.
Aging is characterized by the accumulation of damage to macromolecules and cell architecture that triggers a proinflammatory state in blood and solid tissues, termed inflammaging. ...Finally, we review the emerging evidence that inflammation is involved in brain
Aging is characterized by the accumulation of damage to macromolecules and cell architecture that triggers a proinflammatory state in
DNA damage and repair in age-related inflammation.
Zhao Y, Simon M, Seluanov A, Gorbunova V. Zhao Y, et al. Nat Rev Immunol. 2023 Feb;23(2):75-89. doi: 10.1038/s41577-022-00751-y. Epub 2022 Jul 13. Nat Rev Immunol. 2023. PMID: 35831609 Free PMC article. Review.
However, emerging evidence shows that inflammation is another major consequence of DNA damage. Inflammation is a hallmark of ageing and the driver of multiple age-related diseases. Here, we review the evidence linking DNA damage, inflammation and ag
However, emerging evidence shows that inflammation is another major consequence of DNA damage. Inflammation is a hallmark of …
Inflammation, Aging and Hematopoiesis: A Complex Relationship.
Bousounis P, Bergo V, Trompouki E. Bousounis P, et al. Cells. 2021 Jun 4;10(6):1386. doi: 10.3390/cells10061386. Cells. 2021. PMID: 34199874 Free PMC article. Review.
Although homeostatic levels of inflammatory signaling play an intricate role in HSC maintenance, activation, proliferation, and differentiation, acute or chronic exposure to inflammation can have deleterious effects on HSC function and self-renewal capacity, and bias their …
Although homeostatic levels of inflammatory signaling play an intricate role in HSC maintenance, activation, proliferation, and differentiat …
Gut microbiota and aging.
Mangiola F, Nicoletti A, Gasbarrini A, Ponziani FR. Mangiola F, et al. Eur Rev Med Pharmacol Sci. 2018 Nov;22(21):7404-7413. doi: 10.26355/eurrev_201811_16280. Eur Rev Med Pharmacol Sci. 2018. PMID: 30468488 Free article. Review.
Given this perspective, looking at the mutual influence between microbiota products, inflammation mediators and immune system, the modulation of gut microbiota may help to facilitate a physiological and non-pathological aging process and, perhaps, to contrast the pr …
Given this perspective, looking at the mutual influence between microbiota products, inflammation mediators and immune system, the mo …
The Role of Signaling Pathways of Inflammation and Oxidative Stress in Development of Senescence and Aging Phenotypes in Cardiovascular Disease.
Papaconstantinou J. Papaconstantinou J. Cells. 2019 Nov 4;8(11):1383. doi: 10.3390/cells8111383. Cells. 2019. PMID: 31689891 Free PMC article. Review.
The ASK1-signalosomep38 MAPK and SAPK/JNK signaling networks promote senescence (in vitro) and aging (in vivo, animal models and human cohorts) in response to oxidative stress and inflammation. These networks contribute to the promotion of age-associated cardiovascu …
The ASK1-signalosomep38 MAPK and SAPK/JNK signaling networks promote senescence (in vitro) and aging (in vivo, animal models and huma …
Inflammation, Frailty and Cardiovascular Disease.
Soysal P, Arik F, Smith L, Jackson SE, Isik AT. Soysal P, et al. Adv Exp Med Biol. 2020;1216:55-64. doi: 10.1007/978-3-030-33330-0_7. Adv Exp Med Biol. 2020. PMID: 31894547 Review.
Chronic inflammation, which is called "inflamm-aging" , is characterized by an increased level of inflammatory cytokines in response to physiological and environmental stressors, and causes the immune system to function consistently at a low level, even though it is …
Chronic inflammation, which is called "inflamm-aging" , is characterized by an increased level of inflammatory cytokines in re …
The Skin Epilipidome in Stress, Aging, and Inflammation.
Gruber F, Marchetti-Deschmann M, Kremslehner C, Schosserer M. Gruber F, et al. Front Endocrinol (Lausanne). 2021 Jan 21;11:607076. doi: 10.3389/fendo.2020.607076. eCollection 2020. Front Endocrinol (Lausanne). 2021. PMID: 33551998 Free PMC article. Review.
As the skin is an organ that is frequently exposed to oxidative-, chemical- and thermal stress, and to injury and inflammation, it is an ideal organ to study epilipidome dynamics, their causes, and their biological consequences. ...
As the skin is an organ that is frequently exposed to oxidative-, chemical- and thermal stress, and to injury and inflammation, it is …
Relationship of Aging, Inflammation, and Skeletal Stem Cells and Their Effects on Fracture Repair.
Goodnough LH, Goodman SB. Goodnough LH, et al. Curr Osteoporos Rep. 2022 Oct;20(5):320-325. doi: 10.1007/s11914-022-00742-x. Epub 2022 Sep 21. Curr Osteoporos Rep. 2022. PMID: 36129609 Review.
PURPOSE OF REVIEW: This review summarizes recent investigations into the cellular and molecular effects of skeletal aging on the inflammatory response and stem cell function after fracture. RECENT FINDINGS: Proper regulation of the inflammatory phase of fracture healing is …
PURPOSE OF REVIEW: This review summarizes recent investigations into the cellular and molecular effects of skeletal aging on the infl …
30,833 results
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