Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1983 1
1992 1
1997 1
1998 1
2000 3
2002 3
2003 3
2004 2
2005 1
2006 6
2007 10
2008 12
2009 8
2010 4
2011 6
2012 7
2013 12
2014 15
2015 12
2016 6
2017 8
2018 7
2019 16
2020 10
2021 28
2022 36
2023 34
2024 29
2025 1

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

247 results

Results by year

Filters applied: . Clear all
Page 1
AHCC() Supplementation to Support Immune Function to Clear Persistent Human Papillomavirus Infections.
Smith JA, Gaikwad AA, Mathew L, Rech B, Faro JP, Lucci JA 3rd, Bai Y, Olsen RJ, Byrd TT. Smith JA, et al. Front Oncol. 2022 Jun 22;12:881902. doi: 10.3389/fonc.2022.881902. eCollection 2022. Front Oncol. 2022. PMID: 35814366 Free PMC article.
The AHCC supplement is a proprietary, standardized extract of cultured lentinula edodes mycelia (AHCC(), Amino Up, Ltd., Sapporo, Japan) that has been shown to have unique immune modulatory benefits. ...The duration of AHCC supplementation required beyond the …
The AHCC supplement is a proprietary, standardized extract of cultured lentinula edodes mycelia (AHCC(), Amino Up, Ltd., Sappo …
The Effects of AHCC, a Standardized Extract of Cultured Lentinura edodes Mycelia, on Natural Killer and T Cells in Health and Disease: Reviews on Human and Animal Studies.
Shin MS, Park HJ, Maeda T, Nishioka H, Fujii H, Kang I. Shin MS, et al. J Immunol Res. 2019 Dec 20;2019:3758576. doi: 10.1155/2019/3758576. eCollection 2019. J Immunol Res. 2019. PMID: 31930148 Free PMC article. Review.
AHCC is reported to modulate the numbers and functions of immune cells including natural killer (NK) and T cells which play important roles in host defense, suggesting the possible implication of its supplementation in defending the host against infections and malignancies
AHCC is reported to modulate the numbers and functions of immune cells including natural killer (NK) and T cells which play important
AHCC(), a Standardized Extract of Cultured Lentinula Edodes Mycelia, Promotes the Anti-Tumor Effect of Dual Immune Checkpoint Blockade Effect in Murine Colon Cancer.
Park HJ, Boo S, Park I, Shin MS, Takahashi T, Takanari J, Homma K, Kang I. Park HJ, et al. Front Immunol. 2022 Apr 20;13:875872. doi: 10.3389/fimmu.2022.875872. eCollection 2022. Front Immunol. 2022. PMID: 35514996 Free PMC article.
Here we investigated whether AHCC() promotes the therapeutic effect of immunotherapy in cancers. A combination of oral AHCC() and dual immune checkpoint blockade (DICB), including PD-1/CTLA-4 blockade, had reduced tumor growth and increased granzyme B and Ki-67 expr …
Here we investigated whether AHCC() promotes the therapeutic effect of immunotherapy in cancers. A combination of oral AHCC() …
Nucleotides and AHCC Enhance Th1 Responses In Vitro in Leishmania-Stimulated/Infected Murine Cells.
Dea-Ayuela MA, Segarra S, Serrano DR, Bolás-Fernández F. Dea-Ayuela MA, et al. Molecules. 2020 Aug 27;25(17):3918. doi: 10.3390/molecules25173918. Molecules. 2020. PMID: 32867338 Free PMC article.
The potential leishmanicidal activity of nucleotides and AHCC was assessed by quantifying nitric oxide (NO) production and replication of parasites. ...Lymphocyte proliferation was significantly enhanced by nucleotides, AHCC, and their combinations only after SLA st …
The potential leishmanicidal activity of nucleotides and AHCC was assessed by quantifying nitric oxide (NO) production and replicatio …
Molecular Markers of Response to Anti-PD1 Therapy in Advanced Hepatocellular Carcinoma.
Haber PK, Castet F, Torres-Martin M, Andreu-Oller C, Puigvehí M, Miho M, Radu P, Dufour JF, Verslype C, Zimpel C, Marquardt JU, Galle PR, Vogel A, Bathon M, Meyer T, Labgaa I, Digklia A, Roberts LR, Mohamed Ali MA, Mínguez B, Citterio D, Mazzaferro V, Finkelmeier F, Trojan J, Özdirik B, Müller T, Schmelzle M, Bejjani A, Sung MW, Schwartz ME, Finn RS, Thung S, Villanueva A, Sia D, Llovet JM. Haber PK, et al. Gastroenterology. 2023 Jan;164(1):72-88.e18. doi: 10.1053/j.gastro.2022.09.005. Epub 2022 Sep 12. Gastroenterology. 2023. PMID: 36108710 Free article.
BACKGROUND & AIMS: Single-agent anti-PD1 checkpoint inhibitors convey outstanding clinical benefits in a small fraction (20%) of patients with advanced hepatocellular carcinoma (aHCC) but the molecular mechanisms determining response are unknown. To fill this gap, we h …
BACKGROUND & AIMS: Single-agent anti-PD1 checkpoint inhibitors convey outstanding clinical benefits in a small fraction (20%) of patient …
Oral Supplementation with AHCC(), a Standardized Extract of Cultured Lentinula edodes Mycelia, Enhances Host Resistance against SARS-CoV-2 Infection.
Singh A, Adam A, Rodriguez L, Peng BH, Wang B, Xie X, Shi PY, Homma K, Wang T. Singh A, et al. Pathogens. 2023 Apr 3;12(4):554. doi: 10.3390/pathogens12040554. Pathogens. 2023. PMID: 37111440 Free PMC article.
AHCC treatment also significantly reduced SARS-CoV-2-induced lethality in the K18-hACE2 mice. ...In AHCC-fed BALB/c mice, SARS-CoV-2 specific IgG responses were also enhanced. In summary, AHCC supplementation enhances host resistance against mild and severe C
AHCC treatment also significantly reduced SARS-CoV-2-induced lethality in the K18-hACE2 mice. ...In AHCC-fed BALB/c mice, SARS
Effects of AHCC on Immune and Stress Responses in Healthy Individuals.
Takanari J, Sato A, Waki H, Miyazaki S, Uebaba K, Hisajima T. Takanari J, et al. J Evid Based Integr Med. 2018 Jan-Dec;23:2156587218756511. doi: 10.1177/2156587218756511. J Evid Based Integr Med. 2018. PMID: 29558822 Free PMC article.
AHCC is a functional food from the basidiomycete Lentinula edodes. We evaluated the effects of AHCC on subjects under different kinds of stress and at rest. ...In subjects with chronic mental stress, self-reported "initiation and maintenance of sleep" was significan
AHCC is a functional food from the basidiomycete Lentinula edodes. We evaluated the effects of AHCC on subjects under differen
Short-term and long-term efficacy of 7 targeted therapies for the treatment of advanced hepatocellular carcinoma: a network meta-analysis: Efficacy of 7 targeted therapies for AHCC.
Niu M, Hong D, Ma TC, Chen XW, Han JH, Sun J, Xu K. Niu M, et al. Medicine (Baltimore). 2016 Dec;95(49):e5591. doi: 10.1097/MD.0000000000005591. Medicine (Baltimore). 2016. PMID: 27930578 Free PMC article. Review.
Our study aims to compare the short-term and long-term efficacies of different targeted drugs in advanced hepatocellular carcinoma (AHCC) treatment using a network meta-analysis approach. METHODS: PubMed, Embase, Ovid, EBSCO, and Cochrane central register of controlled tri …
Our study aims to compare the short-term and long-term efficacies of different targeted drugs in advanced hepatocellular carcinoma (AHCC
Effect of Active Hexose Correlated Compound (AHCC) in alcohol-induced liver enzyme elevation.
Kim H, Kim JH, Im JA. Kim H, et al. J Nutr Sci Vitaminol (Tokyo). 2014;60(5):348-56. doi: 10.3177/jnsv.60.348. J Nutr Sci Vitaminol (Tokyo). 2014. PMID: 25744424 Free article. Clinical Trial.
To investigate the effects of Active Hexose Correlated Compound (AHCC) supplementation and the mechanism action of AHCC in patients with alcohol-induced mildly elevated liver enzyme levels, participants were randomly allocated to the placebo, 1 g AHCC, or 3 g …
To investigate the effects of Active Hexose Correlated Compound (AHCC) supplementation and the mechanism action of AHCC in pat …
247 results