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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 1
1973 1
1975 1
1979 2
1980 1
1981 2
1982 3
1983 6
1984 5
1985 4
1986 1
1987 3
1988 4
1989 11
1990 5
1991 10
1992 16
1993 23
1994 26
1995 25
1996 34
1997 29
1998 25
1999 20
2000 24
2001 28
2002 21
2003 22
2004 46
2005 20
2006 41
2007 34
2008 42
2009 33
2010 51
2011 45
2012 51
2013 56
2014 57
2015 49
2016 58
2017 43
2018 63
2019 54
2020 107
2021 114
2022 6
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1,214 results
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Page 1
The airway epithelium in asthma.
Lambrecht BN, Hammad H. Lambrecht BN, et al. Nat Med. 2012 May 4;18(5):684-92. doi: 10.1038/nm.2737. Nat Med. 2012. PMID: 22561832 Review.
Asthma is a T lymphocyte-controlled disease of the airway wall caused by inflammation, overproduction of mucus and airway wall remodeling leading to bronchial hyperreactivity and airway obstruction. The airway epithelium is considered an essenti …
Asthma is a T lymphocyte-controlled disease of the airway wall caused by inflammation, overproduction of mucus and airway wall …
Expression of the SARS-CoV-2 ACE2 Receptor in the Human Airway Epithelium.
Zhang H, Rostami MR, Leopold PL, Mezey JG, O'Beirne SL, Strulovici-Barel Y, Crystal RG. Zhang H, et al. Am J Respir Crit Care Med. 2020 Jul 15;202(2):219-229. doi: 10.1164/rccm.202003-0541OC. Am J Respir Crit Care Med. 2020. PMID: 32432483 Free PMC article.
Rationale: Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease (COVID-19), a predominantly respiratory illness. The first step in SARS-CoV-2 infection is binding of the virus to ACE2 (angiotensin-converting enzyme 2) o …
Rationale: Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease (COVID-19), a predomin …
More Than Just a Barrier: The Immune Functions of the Airway Epithelium in Asthma Pathogenesis.
Frey A, Lunding LP, Ehlers JC, Weckmann M, Zissler UM, Wegmann M. Frey A, et al. Front Immunol. 2020 Apr 28;11:761. doi: 10.3389/fimmu.2020.00761. eCollection 2020. Front Immunol. 2020. PMID: 32411147 Free PMC article. Review.
This symptom-complex arises on the basis of chronic allergic inflammation of the airway wall. Consequently, the airway epithelium is central to the pathogenesis of this disease, because its multiple abilities directly have an impact on the inflammatory respon …
This symptom-complex arises on the basis of chronic allergic inflammation of the airway wall. Consequently, the airway epit
COVID-19, cilia, and smell.
Li W, Li M, Ou G. Li W, et al. FEBS J. 2020 Sep;287(17):3672-3676. doi: 10.1111/febs.15491. Epub 2020 Aug 6. FEBS J. 2020. PMID: 32692465 Free PMC article. Review.
In this Viewpoint, we summarize transmission electron microscopic studies of cilia in virus-infected cells. In the human nasal epithelium, coronavirus infects the ciliated cells and causes deciliation. ...The mucociliary escalator removes inhaled pathogenic particle …
In this Viewpoint, we summarize transmission electron microscopic studies of cilia in virus-infected cells. In the human nasal epi
Respiratory syncytial virus interaction with human airway epithelium.
Villenave R, Shields MD, Power UF. Villenave R, et al. Trends Microbiol. 2013 May;21(5):238-44. doi: 10.1016/j.tim.2013.02.004. Epub 2013 Mar 22. Trends Microbiol. 2013. PMID: 23523320 Review.
Although respiratory syncytial virus (RSV) is a major human respiratory pathogen, our knowledge of how it causes disease in humans is limited. ...Here we review the interaction of RSV with WD-PAEC cultures, the authenticity of the RSV-WD-PAEC models relative to RSV infecti …
Although respiratory syncytial virus (RSV) is a major human respiratory pathogen, our knowledge of how it causes disease in humans is …
Influenza virus-induced lung injury: pathogenesis and implications for treatment.
Herold S, Becker C, Ridge KM, Budinger GR. Herold S, et al. Eur Respir J. 2015 May;45(5):1463-78. doi: 10.1183/09031936.00186214. Epub 2015 Mar 18. Eur Respir J. 2015. PMID: 25792631 Free article. Review.
In humans, infection of the lower respiratory tract of can result in flooding of the alveolar compartment, development of acute respiratory distress syndrome and death from respiratory failure. Influenza-mediated damage of the airway, alveolar epithelium and alveola …
In humans, infection of the lower respiratory tract of can result in flooding of the alveolar compartment, development of acute respiratory …
SARS-CoV replication and pathogenesis in an in vitro model of the human conducting airway epithelium.
Sims AC, Burkett SE, Yount B, Pickles RJ. Sims AC, et al. Virus Res. 2008 Apr;133(1):33-44. doi: 10.1016/j.virusres.2007.03.013. Epub 2007 Apr 23. Virus Res. 2008. PMID: 17451829 Free PMC article. Review.
The second model system, derived from primary cells isolated from human airway epithelium and grown on Transwells, form a pseudostratified mucociliary epithelium that recapitulates the morphological and physiological features of the human conducting airway
The second model system, derived from primary cells isolated from human airway epithelium and grown on Transwells, form a pseu …
The Airway Epithelium-A Central Player in Asthma Pathogenesis.
Calvén J, Ax E, Rådinger M. Calvén J, et al. Int J Mol Sci. 2020 Nov 24;21(23):8907. doi: 10.3390/ijms21238907. Int J Mol Sci. 2020. PMID: 33255348 Free PMC article. Review.
The airway epithelium is the first line of defense and plays an important role in initiating host defense and controlling immune responses. ...Furthermore, many of the identified susceptibility genes for asthma are expressed in the airway epithelium. T …
The airway epithelium is the first line of defense and plays an important role in initiating host defense and controlling immu …
COVID-19 pulmonary pathology: a multi-institutional autopsy cohort from Italy and New York City.
Borczuk AC, Salvatore SP, Seshan SV, Patel SS, Bussel JB, Mostyka M, Elsoukkary S, He B, Del Vecchio C, Fortarezza F, Pezzuto F, Navalesi P, Crisanti A, Fowkes ME, Bryce CH, Calabrese F, Beasley MB. Borczuk AC, et al. Mod Pathol. 2020 Nov;33(11):2156-2168. doi: 10.1038/s41379-020-00661-1. Epub 2020 Sep 2. Mod Pathol. 2020. PMID: 32879413 Free PMC article.
We systematically evaluated lungs of 68 autopsies from 3 institutions in heavily hit areas (2 USA, 1 Italy). Detailed evaluation of several compartments (airways, alveolar walls, airspaces, and vasculature) was performed to determine the range of histologic features. ... …
We systematically evaluated lungs of 68 autopsies from 3 institutions in heavily hit areas (2 USA, 1 Italy). Detailed evaluation of several …
Rhinovirus and Innate Immune Function of Airway Epithelium.
Ganjian H, Rajput C, Elzoheiry M, Sajjan U. Ganjian H, et al. Front Cell Infect Microbiol. 2020 Jun 19;10:277. doi: 10.3389/fcimb.2020.00277. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 32637363 Free PMC article. Review.
Airway epithelial cells are the primary target for rhinovirus and other inhaled pathogens. In response to rhinovirus infection, airway epithelial cells mount both pro-inflammatory responses and antiviral innate immune responses to clear the virus efficiently.
Airway epithelial cells are the primary target for rhinovirus and other inhaled pathogens. In response to rhinovirus infection, ai
1,214 results