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Year Number of Results
1967 1
1968 3
1969 6
1970 5
1971 4
1972 1
1973 8
1974 3
1975 9
1976 11
1977 5
1978 5
1979 12
1980 19
1981 22
1982 18
1983 25
1984 26
1985 38
1986 44
1987 44
1988 58
1989 58
1990 75
1991 102
1992 111
1993 111
1994 120
1995 143
1996 147
1997 139
1998 144
1999 156
2000 179
2001 167
2002 207
2003 251
2004 289
2005 365
2006 395
2007 402
2008 456
2009 455
2010 538
2011 588
2012 612
2013 692
2014 666
2015 749
2016 636
2017 636
2018 595
2019 586
2020 720
2021 631
2022 679
2023 625
2024 585
2025 5

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12,602 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Albumin replacement in patients with severe sepsis or septic shock.
Caironi P, Tognoni G, Masson S, Fumagalli R, Pesenti A, Romero M, Fanizza C, Caspani L, Faenza S, Grasselli G, Iapichino G, Antonelli M, Parrini V, Fiore G, Latini R, Gattinoni L; ALBIOS Study Investigators. Caironi P, et al. N Engl J Med. 2014 Apr 10;370(15):1412-21. doi: 10.1056/NEJMoa1305727. Epub 2014 Mar 18. N Engl J Med. 2014. PMID: 24635772 Free article. Clinical Trial.
METHODS: In this multicenter, open-label trial, we randomly assigned 1818 patients with severe sepsis, in 100 intensive care units (ICUs), to receive either 20% albumin and crystalloid solution or crystalloid solution alone. In the albumin group, the target serum …
METHODS: In this multicenter, open-label trial, we randomly assigned 1818 patients with severe sepsis, in 100 intensive care units (ICUs), t …
A Randomized Trial of Albumin Infusions in Hospitalized Patients with Cirrhosis.
China L, Freemantle N, Forrest E, Kallis Y, Ryder SD, Wright G, Portal AJ, Becares Salles N, Gilroy DW, O'Brien A; ATTIRE Trial Investigators. China L, et al. N Engl J Med. 2021 Mar 4;384(9):808-817. doi: 10.1056/NEJMoa2022166. N Engl J Med. 2021. PMID: 33657293 Clinical Trial.
Preclinical studies provide support for an antiinflammatory role of albumin, but confirmatory large-scale clinical trials are lacking. Whether targeting a serum albumin level of 30 g per liter or greater in these patients with repeated daily infusions of 20% human …
Preclinical studies provide support for an antiinflammatory role of albumin, but confirmatory large-scale clinical trials are lacking …
A comparison of albumin and saline for fluid resuscitation in the intensive care unit.
Finfer S, Bellomo R, Boyce N, French J, Myburgh J, Norton R; SAFE Study Investigators. Finfer S, et al. N Engl J Med. 2004 May 27;350(22):2247-56. doi: 10.1056/NEJMoa040232. N Engl J Med. 2004. PMID: 15163774 Free article. Clinical Trial.
We conducted a multicenter, randomized, double-blind trial to compare the effect of fluid resuscitation with albumin or saline on mortality in a heterogeneous population of patients in the ICU. METHODS: We randomly assigned patients who had been admitted to the ICU to rece …
We conducted a multicenter, randomized, double-blind trial to compare the effect of fluid resuscitation with albumin or saline on mor …
Different Concentrations of Albumin Versus Crystalloid in Patients with Sepsis and Septic Shock: A Meta-Analysis of Randomized Clinical Trials.
Geng L, Tian X, Gao Z, Mao A, Feng L, He C. Geng L, et al. J Intensive Care Med. 2023 Aug;38(8):679-689. doi: 10.1177/08850666231170778. Epub 2023 Apr 20. J Intensive Care Med. 2023. PMID: 37078161 Review.
Further analysis showed a potentially beneficial role of both 4% to 5% and 20% albumin on reducing the mortality of septic patients. The use of 20% albumin significantly decreased the 90-day mortality of septic shock patients (OR 0.81 [0.67, 0.98]; P = .03), which w …
Further analysis showed a potentially beneficial role of both 4% to 5% and 20% albumin on reducing the mortality of septic patients. …
Albumin therapy for acute ischemic stroke: a meta-analysis.
Huang Y, Xiao Z. Huang Y, et al. Neurol Sci. 2021 Jul;42(7):2713-2719. doi: 10.1007/s10072-021-05244-9. Epub 2021 May 4. Neurol Sci. 2021. PMID: 33945037 Review.
Human serum albumin has shown remarkable efficacy in rodent models of ischemic stroke, while results from relevant clinical research on albumin therapy remain controversial. ...Considering pulmonary edema and other complications are more likely to occur in such pati …
Human serum albumin has shown remarkable efficacy in rodent models of ischemic stroke, while results from relevant clinical research …
Effect of 4% Albumin Solution vs Ringer Acetate on Major Adverse Events in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass: A Randomized Clinical Trial.
Pesonen E, Vlasov H, Suojaranta R, Hiippala S, Schramko A, Wilkman E, Eränen T, Arvonen K, Mazanikov M, Salminen US, Meinberg M, Vähäsilta T, Petäjä L, Raivio P, Juvonen T, Pettilä V. Pesonen E, et al. JAMA. 2022 Jul 19;328(3):251-258. doi: 10.1001/jama.2022.10461. JAMA. 2022. PMID: 35852528 Free PMC article. Clinical Trial.
Patients received a median of 2150 mL (IQR, 1598-2700 mL) of study fluid in the albumin group and 3298 mL (IQR, 2669-3500 mL) in the Ringer group. The number of patients with at least 1 major adverse event was 257 of 693 patients (37.1%) in the albumin group and 234 …
Patients received a median of 2150 mL (IQR, 1598-2700 mL) of study fluid in the albumin group and 3298 mL (IQR, 2669-3500 mL) in the …
Diuretic effect of co-administration of furosemide and albumin in comparison to furosemide therapy alone: An updated systematic review and meta-analysis.
Lee TH, Kuo G, Chang CH, Huang YT, Yen CL, Lee CC, Fan PC, Chen JJ. Lee TH, et al. PLoS One. 2021 Dec 1;16(12):e0260312. doi: 10.1371/journal.pone.0260312. eCollection 2021. PLoS One. 2021. PMID: 34851962 Free PMC article.
The diuretic effect of albumin and furosemide co-administration was better in participants with low baseline serum albumin levels (< 2.5 g/dL) and high prescribed albumin infusion doses (> 30 g), and the effect was more significant within 12 hours after …
The diuretic effect of albumin and furosemide co-administration was better in participants with low baseline serum albumin lev …
A randomized trial of albumin infusion to prevent intradialytic hypotension in hospitalized hypoalbuminemic patients.
Macedo E, Karl B, Lee E, Mehta RL. Macedo E, et al. Crit Care. 2021 Jan 6;25(1):18. doi: 10.1186/s13054-020-03441-0. Crit Care. 2021. PMID: 33407747 Free PMC article. Clinical Trial.

We evaluated the efficacy of albumin infusion in preventing IDH during IHD in hypoalbuminemic inpatients. METHODS: A randomized, crossover trial was performed in 65 AKI or ESKD patients with hypoalbuminemia (albumin < 3 g/dl) who required HD during hospitalizatio

…
We evaluated the efficacy of albumin infusion in preventing IDH during IHD in hypoalbuminemic inpatients. METHODS: A randomized, cros …
Hemoglobin, albumin, lymphocyte, and platelet (HALP) score and cancer prognosis: A systematic review and meta-analysis of 13,110 patients.
Xu H, Zheng X, Ai J, Yang L. Xu H, et al. Int Immunopharmacol. 2023 Jan;114:109496. doi: 10.1016/j.intimp.2022.109496. Epub 2022 Nov 30. Int Immunopharmacol. 2023. PMID: 36462339 Review.
BACKGROUND AND AIMS: We sought to explore the prognostic role of the hemoglobin, albumin, lymphocyte, and platelet (HALP) score on survival outcomes in patients with solid tumors by performing a systematic review and meta-analysis. ...
BACKGROUND AND AIMS: We sought to explore the prognostic role of the hemoglobin, albumin, lymphocyte, and platelet (HALP) score on su …
A randomized-controlled trial comparing 20% albumin to plasmalyte in patients with cirrhosis and sepsis-induced hypotension [ALPS trial].
Maiwall R, Kumar A, Pasupuleti SSR, Hidam AK, Tevethia H, Kumar G, Sahney A, Mitra LG, Sarin SK. Maiwall R, et al. J Hepatol. 2022 Sep;77(3):670-682. doi: 10.1016/j.jhep.2022.03.043. Epub 2022 Apr 20. J Hepatol. 2022. PMID: 35460725 Clinical Trial.
BACKGROUND & AIMS: The choice of resuscitation fluid in patients with cirrhosis and sepsis-induced hypotension is unclear. 5% albumin was superior to normal saline in the FRISC study. We compared the efficacy and safety of 20% albumin, which has greater oncotic …
BACKGROUND & AIMS: The choice of resuscitation fluid in patients with cirrhosis and sepsis-induced hypotension is unclear. 5% albumin …
12,602 results
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