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Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS.

Jourdain AA, Begg BE, Mick E, Shah H, Calvo SE, Skinner OS, Sharma R, Blue SM, Yeo GW, Burge CB, Mootha VK. Jourdain AA, et al. Mol Cell. 2021 May 6;81(9):1905-1919.e12. doi: 10.1016/j.molcel.2021.02.033. Epub 2021 Apr 13. Mol Cell. 2021. PMID: 33852893 Free PMC article.

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MitoCarta3.0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations.

Rath S, Sharma R, Gupta R, Ast T, Chan C, Durham TJ, Goodman RP, Grabarek Z, Haas ME, Hung WHW, Joshi PR, Jourdain AA, Kim SH, Kotrys AV, Lam SS, McCoy JG, Meisel JD, Miranda M, Panda A, Patgiri A, Rogers R, Sadre S, Shah H, Skinner OS, To TL, Walker MA, Wang H, Ward PS, Wengrod J, Yuan CC, Calvo SE, Mootha VK. Rath S, et al. Among authors: jourdain aa. Nucleic Acids Res. 2021 Jan 8;49(D1):D1541-D1547. doi: 10.1093/nar/gkaa1011. Nucleic Acids Res. 2021. PMID: 33174596 Free PMC article.

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Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies.

Guièze R, Liu VM, Rosebrock D, Jourdain AA, Hernández-Sánchez M, Martinez Zurita A, Sun J, Ten Hacken E, Baranowski K, Thompson PA, Heo JM, Cartun Z, Aygün O, Iorgulescu JB, Zhang W, Notarangelo G, Livitz D, Li S, Davids MS, Biran A, Fernandes SM, Brown JR, Lako A, Ciantra ZB, Lawlor MA, Keskin DB, Udeshi ND, Wierda WG, Livak KJ, Letai AG, Neuberg D, Harper JW, Carr SA, Piccioni F, Ott CJ, Leshchiner I, Johannessen CM, Doench J, Mootha VK, Getz G, Wu CJ. Guièze R, et al. Among authors: jourdain aa. Cancer Cell. 2019 Oct 14;36(4):369-384.e13. doi: 10.1016/j.ccell.2019.08.005. Epub 2019 Sep 19. Cancer Cell. 2019. PMID: 31543463 Free PMC article.

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A Genome-wide CRISPR Death Screen Identifies Genes Essential for Oxidative Phosphorylation.

Arroyo JD, Jourdain AA, Calvo SE, Ballarano CA, Doench JG, Root DE, Mootha VK. Arroyo JD, et al. Among authors: jourdain aa. Cell Metab. 2016 Dec 13;24(6):875-885. doi: 10.1016/j.cmet.2016.08.017. Epub 2016 Sep 22. Cell Metab. 2016. PMID: 27667664 Free PMC article.

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Mitochondrial outer-membrane permeabilization and remodelling in apoptosis.

Jourdain A, Martinou JC. Jourdain A, et al. Int J Biochem Cell Biol. 2009 Oct;41(10):1884-9. doi: 10.1016/j.biocel.2009.05.001. Epub 2009 May 9. Int J Biochem Cell Biol. 2009. PMID: 19439192 Review.

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The FASTK family of proteins: emerging regulators of mitochondrial RNA biology.

Jourdain AA, Popow J, de la Fuente MA, Martinou JC, Anderson P, Simarro M. Jourdain AA, et al. Nucleic Acids Res. 2017 Nov 2;45(19):10941-10947. doi: 10.1093/nar/gkx772. Nucleic Acids Res. 2017. PMID: 29036396 Free PMC article. Review.

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Mitochondrial RNA granules: Compartmentalizing mitochondrial gene expression.

Jourdain AA, Boehm E, Maundrell K, Martinou JC. Jourdain AA, et al. J Cell Biol. 2016 Mar 14;212(6):611-4. doi: 10.1083/jcb.201507125. Epub 2016 Mar 7. J Cell Biol. 2016. PMID: 26953349 Free PMC article.

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Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell.

Mick E, Titov DV, Skinner OS, Sharma R, Jourdain AA, Mootha VK. Mick E, et al. Among authors: jourdain aa. Elife. 2020 May 28;9:e49178. doi: 10.7554/eLife.49178. Elife. 2020. PMID: 32463360 Free PMC article.

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EXD2 governs germ stem cell homeostasis and lifespan by promoting mitoribosome integrity and translation.

Silva J, Aivio S, Knobel PA, Bailey LJ, Casali A, Vinaixa M, Garcia-Cao I, Coyaud É, Jourdain AA, Pérez-Ferreros P, Rojas AM, Antolin-Fontes A, Samino-Gené S, Raught B, González-Reyes A, Ribas de Pouplana L, Doherty AJ, Yanes O, Stracker TH. Silva J, et al. Among authors: jourdain aa. Nat Cell Biol. 2018 Feb;20(2):162-174. doi: 10.1038/s41556-017-0016-9. Epub 2018 Jan 15. Nat Cell Biol. 2018. PMID: 29335528 Free article.

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GRSF1 regulates RNA processing in mitochondrial RNA granules.

Jourdain AA, Koppen M, Wydro M, Rodley CD, Lightowlers RN, Chrzanowska-Lightowlers ZM, Martinou JC. Jourdain AA, et al. Cell Metab. 2013 Mar 5;17(3):399-410. doi: 10.1016/j.cmet.2013.02.005. Cell Metab. 2013. PMID: 23473034 Free PMC article.

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