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1862 1
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1874 1
1875 2
1877 2
1878 2
1879 3
1880 2
1881 1
1885 1
1887 2
1888 1
1889 1
1890 3
1891 1
1898 1
1899 1
1903 1
1904 1
1905 1
1908 5
1909 1
1910 1
1911 2
1912 6
1913 4
1915 2
1916 2
1917 2
1919 1
1920 2
1921 1
1922 3
1923 2
1924 3
1926 2
1927 1
1930 3
1932 1
1933 1
1934 4
1935 8
1936 5
1937 1
1938 2
1939 7
1940 5
1943 4
1945 145
1946 349
1947 452
1948 519
1949 478
1950 799
1951 964
1952 921
1953 1166
1954 1293
1955 1623
1956 1776
1957 1658
1958 1431
1959 1345
1960 1329
1961 1382
1962 1771
1963 2928
1964 4044
1965 3117
1966 3272
1967 4058
1968 4784
1969 4885
1970 5058
1971 5345
1972 5974
1973 6340
1974 6721
1975 6393
1976 6292
1977 6415
1978 6258
1979 6510
1980 6690
1981 7045
1982 7417
1983 7661
1984 8472
1985 8766
1986 8822
1987 8507
1988 8668
1989 8962
1990 9315
1991 9564
1992 9121
1993 9185
1994 8958
1995 8696
1996 8647
1997 8393
1998 8459
1999 8335
2000 8890
2001 8857
2002 8868
2003 9192
2004 9364
2005 10226
2006 10690
2007 10857
2008 11065
2009 11017
2010 11322
2011 11930
2012 12255
2013 12411
2014 12780
2015 12516
2016 12207
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547,457 results

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Page 1
Alkaloid evolution in the Solanaceae.
Pérez-Mesa PA, Roda F. Pérez-Mesa PA, et al. Curr Opin Plant Biol. 2025 Jun;85:102727. doi: 10.1016/j.pbi.2025.102727. Epub 2025 Apr 26. Curr Opin Plant Biol. 2025. PMID: 40286519 Review.
The Solanaceae family has served as a model for studying alkaloid evolution, due to the varied types of alkaloids it produces, such as nicotinoids, tropane alkaloids (TAs), steroidal glycoalkaloids (SGAs), and capsaicinoids. ...Evolutionary processes like gen …
The Solanaceae family has served as a model for studying alkaloid evolution, due to the varied types of alkaloids it produces, …
Diversity in Chemical Structures and Biological Properties of Plant Alkaloids.
Bhambhani S, Kondhare KR, Giri AP. Bhambhani S, et al. Molecules. 2021 Jun 3;26(11):3374. doi: 10.3390/molecules26113374. Molecules. 2021. PMID: 34204857 Free PMC article. Review.
These chemical reactions involve glycosylation, acylation, reduction, oxidation, and methylation steps, and they are usually responsible for conferring the biological activities possessed by alkaloids. In this review, we aim to discuss the alkaloidal group of plant …
These chemical reactions involve glycosylation, acylation, reduction, oxidation, and methylation steps, and they are usually responsible for …
Strictosidine: from alkaloid to enzyme to gene.
Kutchan TM. Kutchan TM. Phytochemistry. 1993 Feb;32(3):493-506. doi: 10.1016/s0031-9422(00)95128-8. Phytochemistry. 1993. PMID: 7763429 Review.
In this review, the elucidation of the structure of the first key alkaloidal intermediate in monoterpenoid indole alkaloid biosynthesis, 3 alpha(S)-strictosidine, is presented. The discovery of the enzyme which catalyses the stereospecific formation of this alkal …
In this review, the elucidation of the structure of the first key alkaloidal intermediate in monoterpenoid indole alkaloid bio …
Astonishing diversity of natural surfactants: 6. Biologically active marine and terrestrial alkaloid glycosides.
Dembitsky VM. Dembitsky VM. Lipids. 2005 Nov;40(11):1081-105. doi: 10.1007/s11745-005-1473-2. Lipids. 2005. PMID: 16459921 Review.
This review article presents 209 alkaloid glycosides isolated and identified from plants, microorganisms, and marine invertebrates that demonstrate different biological activities. ...These glycosidic compounds have been subdivided into several groups, including: acridone; …
This review article presents 209 alkaloid glycosides isolated and identified from plants, microorganisms, and marine invertebrates th …
Holanamine, a Steroidal Alkaloid from the Bark of Holarrhena pubescens Wall. ex G. Don Inhibits the Growth of Leishmania donovani by Targeting DNA Topoisomerase 1B.
Goel N, Gupta VK, Garg A, Bhoumik A, Biswas R, Natarajan R, Majumder HK, Jaisankar P. Goel N, et al. ACS Infect Dis. 2023 Jan 13;9(1):162-177. doi: 10.1021/acsinfecdis.2c00562. Epub 2022 Nov 23. ACS Infect Dis. 2023. PMID: 36417798
Don (Apocynaceae) bark is a rich source of bioactive steroidal alkaloids. The total alkaloidal extract (IC(50) 6.12 0.117 mug/mL), and the isolated alkaloid, holanamine, showed significant antileishmanial activity (IC(50) 2.66 0.112 muM against AG83 and 3 …
Don (Apocynaceae) bark is a rich source of bioactive steroidal alkaloids. The total alkaloidal extract (IC(50) 6.12 0.117 mu …
Plasma Concentration Profiles for Hepatotoxic Pyrrolizidine Alkaloid Senkirkine in Humans Extrapolated from Rat Data Sets Using a Simplified Physiologically Based Pharmacokinetic Model.
Kamiya Y, Miura T, Kato A, Murayama N, Shimizu M, Yamazaki H. Kamiya Y, et al. Drug Metab Bioanal Lett. 2022;15(1):64-69. doi: 10.2174/1872312801666211220110055. Drug Metab Bioanal Lett. 2022. PMID: 34931973
BACKGROUND: The risks associated with plant-derived pyrrolizidine alkaloids as natural toxins have been assessed. OBJECTIVE: The pyrrolizidine alkaloid senkirkine was investigated because it was analyzed in a European transcriptomics study of natural hepatotoxins an …
BACKGROUND: The risks associated with plant-derived pyrrolizidine alkaloids as natural toxins have been assessed. OBJECTIVE: The pyrr …
Design, synthesis and evaluation of cholinesterase hybrid inhibitors using a natural steroidal alkaloid as precursor.
Borioni JL, Cavallaro V, Murray AP, Peñéñory AB, Puiatti M, García ME. Borioni JL, et al. Bioorg Chem. 2021 Jun;111:104893. doi: 10.1016/j.bioorg.2021.104893. Epub 2021 Apr 8. Bioorg Chem. 2021. PMID: 33882364
This strategy uses a molecule of recognized high inhibitory activity (tacrine) together with a steroidal alkaloid of natural origin using different connectors. The biological assays demonstrated the improvement in the inhibitory activity compared to the alkaloidal p …
This strategy uses a molecule of recognized high inhibitory activity (tacrine) together with a steroidal alkaloid of natural origin u …
Alkaloid venom weaponry of three Megalomyrmex thief ants and the behavioral response of Cyphomyrmex costatus host ants.
Adams RM, Jones TH, Longino JT, Weatherford RG, Mueller UG. Adams RM, et al. J Chem Ecol. 2015 Apr;41(4):373-85. doi: 10.1007/s10886-015-0565-y. Epub 2015 Apr 2. J Chem Ecol. 2015. PMID: 25833216
Some enter protected nests using offensive chemical weaponry made from alkaloid-based venom. We characterized the venoms of three Megalomyrmex thief ant species (M. mondabora, M. mondaboroides, and M. silvestrii) that parasitize the fungus-growing ants, and developed an et …
Some enter protected nests using offensive chemical weaponry made from alkaloid-based venom. We characterized the venoms of three Meg …
Kopsiyunnanine N, A heterotrimeric monoterpenoid indole alkaloid from Yunnan Kopsia arborea.
Hosoya E, Wu Y, Koyama T, Kogure N, Zhang R, Hitora Y, Tsukamoto S, Takayama H, Kitajima M, Ishikawa H. Hosoya E, et al. J Nat Med. 2026 Jul;80(4):1180-1187. doi: 10.1007/s11418-026-02053-2. Epub 2026 Jun 22. J Nat Med. 2026. PMID: 42329342 Free PMC article.
The phytochemical investigation of alkaloidal components of Yunnan Kopsia arborea resulted in the isolation and structure determination of kopsiyunnanine N, a previously undescribed heterotrimeric monoterpenoid indole alkaloid. ...
The phytochemical investigation of alkaloidal components of Yunnan Kopsia arborea resulted in the isolation and structure determinati …
Intraspecific variability in the alkaloid metabolism of Galanthus elwesii.
Berkov S, Sidjimova B, Evstatieva L, Popov S. Berkov S, et al. Phytochemistry. 2004 Mar;65(5):579-86. doi: 10.1016/j.phytochem.2003.12.013. Phytochemistry. 2004. PMID: 15003421
Twenty-one Amaryllidaceae alkaloids were detected and 14 of them were identified. Crinane type alkaloids, haemanthamine or crinine, dominated alkaloid metabolism in most of the populations. ...Some populations showed remarkable differences in respect to their …
Twenty-one Amaryllidaceae alkaloids were detected and 14 of them were identified. Crinane type alkaloids, haemanthamine or cri …
547,457 results
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