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Allicin ameliorates imiquimod-induced psoriasis-like skin inflammation via disturbing the interaction of keratinocytes with IL-17A.
Zhang L, Ma X, Shi R, Zhang L, Zhao R, Duan R, Qin Y, Gao S, Li X, Duan J, Li J. Zhang L, et al. Br J Pharmacol. 2023 Mar;180(5):628-646. doi: 10.1111/bph.15983. Epub 2022 Nov 30. Br J Pharmacol. 2023. PMID: 36355777 Free article.
Skin sensitization tests were evaluated on guinea pigs. Toxicological studies and skin irritation tests were assessed by consecutive topical allicin alone on the skin of rabbits. ...Importantly, topical administration of allicin did not cause …
Skin sensitization tests were evaluated on guinea pigs. Toxicological studies and skin irritation tests were assessed by conse …
The Identification of Multidrug-Resistant Microorganisms including Bergeyella zoohelcum Acquired from the Skin/Prosthetic Interface of Amputees and Their Susceptibility to Medihoney and Garlic Extract (Allicin).
Harsent R, Macleod J, Rowlands RS, Smith PM, Rushmere N, Blaxland J. Harsent R, et al. Microorganisms. 2022 Jan 26;10(2):299. doi: 10.3390/microorganisms10020299. Microorganisms. 2022. PMID: 35208754 Free PMC article.
Users of prosthetic devices face the accumulation of potentially drug-resistant pathogenic bacteria on the skin/prosthesis interface. In this study, we took surface swabs of the skin/prosthesis interface of eleven disabled athletes to identify microorganisms present …
Users of prosthetic devices face the accumulation of potentially drug-resistant pathogenic bacteria on the skin/prosthesis interface. …
Ajoene (natural garlic compound): a new anti-leukaemia agent for AML therapy.
Hassan HT. Hassan HT. Leuk Res. 2004 Jul;28(7):667-71. doi: 10.1016/j.leukres.2003.10.008. Leuk Res. 2004. PMID: 15158086 Review.
Several garlic compounds including allicin and its corresponding sulfide inhibit the proliferation and induce apoptosis of several human non-leukaemia malignant cells including breast, bladder, colorectal, hepatic, prostate cancer, lymphoma and skin tumour ce …
Several garlic compounds including allicin and its corresponding sulfide inhibit the proliferation and induce apoptosis of sev …
Garlic constituents for cancer prevention and therapy: From phytochemistry to novel formulations.
Mondal A, Banerjee S, Bose S, Mazumder S, Haber RA, Farzaei MH, Bishayee A. Mondal A, et al. Pharmacol Res. 2022 Jan;175:105837. doi: 10.1016/j.phrs.2021.105837. Epub 2021 Aug 24. Pharmacol Res. 2022. PMID: 34450316 Review.
Taking into account the multi-targeted actions and absence of considerable toxicity, a few active metabolites of garlic are probably to play crucial roles in the killing of cancerous cells. Garlic contains several bioactive molecules with anticancer actions and thes …
Taking into account the multi-targeted actions and absence of considerable toxicity, a few active metabolites of garlic are probably …
Garlic extracts prevent oxidative stress, hypertrophy and apoptosis in cardiomyocytes: a role for nitric oxide and hydrogen sulfide.
Louis XL, Murphy R, Thandapilly SJ, Yu L, Netticadan T. Louis XL, et al. BMC Complement Altern Med. 2012 Aug 29;12:140. doi: 10.1186/1472-6882-12-140. BMC Complement Altern Med. 2012. PMID: 22931510 Free PMC article.
Pharmacological blockade of nitric oxide (NO) and hydrogen sulfide (H2S) were used to elucidate the mechanism of action of garlic extracts. Garlic extract samples were also tested for alliin and allicin concentrations. ...Allicin and alliin concentrati …
Pharmacological blockade of nitric oxide (NO) and hydrogen sulfide (H2S) were used to elucidate the mechanism of action of garlic ext …
Formulation, Evaluation and Optimization of Antimicrobial Potential of Herbal Cream Containing Allium sativum, Moringa oleifera Extracts and Thymus vulgaris Oil.
Sheikh M, Khan HM, Khan MUZ, Sharif A. Sheikh M, et al. Curr Pharm Biotechnol. 2024;25(3):365-383. doi: 10.2174/1389201024666230504124838. Curr Pharm Biotechnol. 2024. PMID: 37143275
METHODS: The herbal cream was formulated by using aqueous extracts of garlic (Allium sativum), moringa (Moringa oleifera) and essential oil of thyme (Thymus vulgaris). ...P. aeruginosa, B. subtilis, E. coli, S. aureus, and S. pneumonia are commonly found in fresh wounds. R …
METHODS: The herbal cream was formulated by using aqueous extracts of garlic (Allium sativum), moringa (Moringa oleifera) and essenti …
In Vivo Antitumor Activity of Allicin in a Pediatric Neuroblastoma Patient-derived Xenograft (PDX) Mouse Model.
Schultz CR, Gruhlke MCH, Slusarenko AJ, Bachmann AS. Schultz CR, et al. In Vivo. 2025 May-Jun;39(3):1283-1292. doi: 10.21873/invivo.13932. In Vivo. 2025. PMID: 40295032 Free PMC article.
BACKGROUND/AIM: Allicin is a small-molecule natural product found in garlic (Allium sativum). We previously showed that allicin inhibits ornithine decarboxylase (ODC) in vitro and induces apoptotic cell death in pediatric neuroblastoma (NB) cancer cell cultur …
BACKGROUND/AIM: Allicin is a small-molecule natural product found in garlic (Allium sativum). We previously showed that all …
Development and Application of a Novel 'Green' Antibacterial Black Garlic (Allium sativum)-Based Nanogel in Epidermal Wound Healing( ).
Sadaf M, Das A, Das S, Saha S, Kuotsu K, Bhattacharjee P. Sadaf M, et al. Food Technol Biotechnol. 2025 Jun;63(2):177-189. doi: 10.17113/ftb.63.02.25.8873. Food Technol Biotechnol. 2025. PMID: 40735159 Free PMC article.
The enzyme alliinase, which converts alliin to allicin, is deactivated at moderately high temperature, thus stripping away the typical pungent odour of fresh garlic during fermentation and rendering black garlic devoid of the typical garlic-like smell. …
The enzyme alliinase, which converts alliin to allicin, is deactivated at moderately high temperature, thus stripping away the typica …
Transcutaneous allicin oleogel restores energy homeostasis for obesity treatment.
Xu QG, Gu ZY, Chen WJ, Liu H, Li ZY, Cai WL, Huang J, Muhitdinov B, Liu EG, Aisa HA, Huang YZ. Xu QG, et al. Acta Pharmacol Sin. 2026 Aug;47(8):2282-2296. doi: 10.1038/s41401-026-01768-y. Epub 2026 Mar 30. Acta Pharmacol Sin. 2026. PMID: 41912621
Allicin, a bioactive compound derived from garlic, exhibits therapeutic potential against metabolic disorders but is hindered by instability and a pungent odor, limiting its clinical application. This study develops an allicin oleogel (OG) formulation, levera …
Allicin, a bioactive compound derived from garlic, exhibits therapeutic potential against metabolic disorders but is hindered …
Fungal infection control by garlic extracts (Allium sativum L.) and modulation of peritoneal macrophages activity in murine model of sporotrichosis.
Burian JP, Sacramento LVS, Carlos IZ. Burian JP, et al. Braz J Biol. 2017 Nov;77(4):848-855. doi: 10.1590/1519-6984.03716. Epub 2017 May 4. Braz J Biol. 2017. PMID: 28492800 Free article.
Allicin is the main component of garlic, being attributed to it the most of its biological activities, such as bactericidal, antifungal and antiviral actions. ...Mice that consumed garlic responded more effectively to fight against the infection....
Allicin is the main component of garlic, being attributed to it the most of its biological activities, such as bactericidal, a …
12 results