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Therapeutic effect of allicin in a mouse model of intracerebral hemorrhage.
Atef Y, Kinoshita K, Ichihara Y, Ushida K, Hirata Y, Kurauchi Y, Seki T, Katsuki H. Atef Y, et al. J Pharmacol Sci. 2023 Dec;153(4):208-214. doi: 10.1016/j.jphs.2023.09.007. Epub 2023 Oct 2. J Pharmacol Sci. 2023. PMID: 37973218 Free article.
In addition, allicin inhibited accumulation of activated microglia/macrophages around the hematoma and infiltration of neutrophils within the hematoma. ...Moreover, ICH-induced increase of malondialdehyde as well as decrease of total glutathione in the brain was att …
In addition, allicin inhibited accumulation of activated microglia/macrophages around the hematoma and infiltration of neutrop …
Allicin attenuated chronic social defeat stress induced depressive-like behaviors through suppression of NLRP3 inflammasome.
Gao W, Wang W, Liu G, Zhang J, Yang J, Deng Z. Gao W, et al. Metab Brain Dis. 2019 Feb;34(1):319-329. doi: 10.1007/s11011-018-0342-z. Epub 2018 Dec 4. Metab Brain Dis. 2019. PMID: 30515710
Thus, our present study for the first time investigated the potential antidepressant effects and the mechanisms of allicin on the CSDS mice model. Thirty minutes before social defeat stress, allicin (2, 10, 50 mg/kg) was treated by intraperitoneal injection. ...The …
Thus, our present study for the first time investigated the potential antidepressant effects and the mechanisms of allicin on the CSD …
A combination of inhibiting microglia activity and remodeling gut microenvironment suppresses the development and progression of experimental autoimmune uveitis.
Zhou J, Yang J, Dai M, Lin D, Zhang R, Liu H, Yu A, Vakal S, Wang Y, Li X. Zhou J, et al. Biochem Pharmacol. 2020 Oct;180:114108. doi: 10.1016/j.bcp.2020.114108. Epub 2020 Jun 20. Biochem Pharmacol. 2020. PMID: 32569628
ABHU2SB and promoting a functional shift in the gut via reversing the levels of L-proline, allicin, aceturic acid, xanthine, and leukotriene B4, and especially increasing the production of propionic acid, histamine, and pantothenic acid. At last, we revealed that minocycli …
ABHU2SB and promoting a functional shift in the gut via reversing the levels of L-proline, allicin, aceturic acid, xanthine, and leuk …
Evaluating the anti-neuroinflammatory capacity of raw and steamed garlic as well as five organosulfur compounds.
Ho SC, Su MS. Ho SC, et al. Molecules. 2014 Oct 31;19(11):17697-714. doi: 10.3390/molecules191117697. Molecules. 2014. PMID: 25365295 Free PMC article.
The anti-neuroinflammatory capacities of raw and steamed garlic extracts as well as five organosulfur compounds (OSCs) were examined in lipopolysaccharide (LPS)-stimulated BV2 microglia. According to those results, steaming pretreatment blocked the formation of alliinase-c …
The anti-neuroinflammatory capacities of raw and steamed garlic extracts as well as five organosulfur compounds (OSCs) were examined in lipo …