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Page 1
Dietary factors, hormesis and health.
Mattson MP. Mattson MP. Ageing Res Rev. 2008 Jan;7(1):43-8. doi: 10.1016/j.arr.2007.08.004. Epub 2007 Sep 1. Ageing Res Rev. 2008. PMID: 17913594 Free PMC article. Review.
Examples include: activation of the Nrf-2 -- ARE pathway by sulforaphane and curcumin; activation of TRP ion channels by allicin and capsaicin; and activation of sirtuin-1 by resveratrol. Research that establishes dose response and kinetic characteristics of …
Examples include: activation of the Nrf-2 -- ARE pathway by sulforaphane and curcumin; activation of TRP ion channels by allicin and …
Allicin Alleviates Mitochondrial Dysfunction in Acrylamide-Induced Rat Kidney Involving the Regulation of SIRT1.
Li L, Wang Z, Li Y, Ma F, Wang X, Yan H, Li W, Pang Y, Yuan Y. Li L, et al. J Agric Food Chem. 2023 Oct 25;71(42):15785-15795. doi: 10.1021/acs.jafc.3c04687. Epub 2023 Oct 13. J Agric Food Chem. 2023. PMID: 37830900
Acrylamide (AA), commonly formed in carbohydrate-rich thermally processed foods, exerts harmful effects on the kidney. Allicin, from crushed garlic cloves, exhibits strong biological activities. In the current study, the protection mechanisms of allicin against AA-c …
Acrylamide (AA), commonly formed in carbohydrate-rich thermally processed foods, exerts harmful effects on the kidney. Allicin, from …
Diallyl trisulfide induces pro-apoptotic autophagy via the AMPK/SIRT1 signalling pathway in human hepatocellular carcinoma HepG2 cell line.
Sun S, Liu X, Wei X, Zhang S, Wang W. Sun S, et al. Food Nutr Res. 2023 May 19;66. doi: 10.29219/fnr.v66.8981. eCollection 2022. Food Nutr Res. 2023. PMID: 37868628 Free PMC article.
Diallyl trisulfide (DATS), the main chemical constituent of allicin, affects tumour development by regulating cell apoptosis. Allicin-induced autophagy could contribute to apoptosis in HepG2 cells. ...Autophagy and the AMP-activated protein kinase (AMPK)/NAD-depende …
Diallyl trisulfide (DATS), the main chemical constituent of allicin, affects tumour development by regulating cell apoptosis. Alli …
Allicin Alleviates Lead-Induced Bone Loss by Preventing Oxidative Stress and Osteoclastogenesis Via SIRT1/FOXO1 Pathway in Mice.
Li D, Liang H, Li Y, Zhang J, Qiao L, Luo H. Li D, et al. Biol Trace Elem Res. 2021 Jan;199(1):237-243. doi: 10.1007/s12011-020-02136-5. Epub 2020 Apr 21. Biol Trace Elem Res. 2021. PMID: 32314144
The aim of this study was to investigate the effects of allicin on lead-induced bone loss in mice. Male C57BL/6 J mice (3-weeks-old) were randomly divided into four groups: control group, lead group, allicin+lead group, and allicin group. ...Moreover, we foun …
The aim of this study was to investigate the effects of allicin on lead-induced bone loss in mice. Male C57BL/6 J mice (3-weeks-old) …
Inhibition of Hydrogen Peroxide-Induced Human Umbilical Vein Endothelial Cells Aging by Allicin Depends on Sirtuin1 Activation.
Lin XL, Liu Y, Liu M, Hu H, Pan Y, Fan XJ, Hu XM, Zou WW. Lin XL, et al. Med Sci Monit. 2017 Jan 31;23:563-570. doi: 10.12659/msm.899730. Med Sci Monit. 2017. PMID: 28139552 Free PMC article.
BACKGROUND The abnormal activity of Sirtuin 1 (Sirt1) is closely related to the aging of vascular endothelial cells. As a bioactive molecule, allicin has antioxidant, anti-inflammatory, and lipid-regulating mechanisms. ...These effects were significantly alle …
BACKGROUND The abnormal activity of Sirtuin 1 (Sirt1) is closely related to the aging of vascular endothelial cells. As a bioa …