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Year Number of Results
1996 2
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Page 1
Menopause and Mental Health.
Crockett C, Lichtveld G, Macdonald R, Newson L, Rampling KJ. Crockett C, et al. Adv Ther. 2026 Jan;43(1):98-108. doi: 10.1007/s12325-025-03427-w. Epub 2025 Nov 21. Adv Ther. 2026. PMID: 41269515 Free PMC article. Review.
Menopause is more than simply the end of menstrual cycles or having hot flushes-it marks a time of profound hormonal change which can cause a range of symptoms from poor sleep to anxiety, low mood, cognitive decline and difficulties with memory. These effects can be life-a …
Menopause is more than simply the end of menstrual cycles or having hot flushes-it marks a time of profound hormonal change which can cause …
Neurosteroids and behavior.
Engel SR, Grant KA. Engel SR, et al. Int Rev Neurobiol. 2001;46:321-48. doi: 10.1016/s0074-7742(01)46067-3. Int Rev Neurobiol. 2001. PMID: 11599304 Review.
Neurosteroids affect two of the most widely distributed neurotransmitter and receptor systems in the central nervous system (CNS): gamma-aminobutyric acid (GABA) and glutamate. This ability of this class of compounds to affect both the primary excitato …
Neurosteroids affect two of the most widely distributed neurotransmitter and receptor systems in the central nervous system (CNS): gamma …
Progesterone-induced changes in sleep in male subjects.
Friess E, Tagaya H, Trachsel L, Holsboer F, Rupprecht R. Friess E, et al. Am J Physiol. 1997 May;272(5 Pt 1):E885-91. doi: 10.1152/ajpendo.1997.272.5.E885. Am J Physiol. 1997. PMID: 9176190 Clinical Trial.
It has been been suggested that this effect is mediated via neuroactive metabolites that interact with the gamma-aminobutyric, acidA (GABAA) receptor complex. To investigate the effects of progesterone administration on the sleep electroencephalogram ( …
It has been been suggested that this effect is mediated via neuroactive metabolites that interact with the gamma-aminobutyric, …
Inhibitory respiratory responses to progesterone and allopregnanolone in newborn rats chronically treated with caffeine.
Uppari N, Joseph V, Bairam A. Uppari N, et al. J Physiol. 2016 Jan 15;594(2):373-89. doi: 10.1113/JP270914. Epub 2015 Dec 14. J Physiol. 2016. PMID: 26497835 Free PMC article.
We conclude that combining progesterone and chronic caffeine is not an option in preterm neonates, unless the effects of allopregnanolone can be counteracted. ...In caffeine-treated rats, bicuculline enhanced ventilation, while allopregnanolone decreased vent …
We conclude that combining progesterone and chronic caffeine is not an option in preterm neonates, unless the effects of allopregn …
Progesterone induces changes in sleep comparable to those of agonistic GABAA receptor modulators.
Lancel M, Faulhaber J, Holsboer F, Rupprecht R. Lancel M, et al. Am J Physiol. 1996 Oct;271(4 Pt 1):E763-72. doi: 10.1152/ajpendo.1996.271.4.E763. Am J Physiol. 1996. PMID: 8897866
Progesterone also elicited dose-related changes in sleep state-specific electroencephalogram (EEG) power densities. ...The effects were maximal during the first postinjection hours. The concentrations of progesterone and the progesterone metabolites 3 …
Progesterone also elicited dose-related changes in sleep state-specific electroencephalogram (EEG) power densities. ...The eff …
Allopregnanolone affects sleep in a benzodiazepine-like fashion.
Lancel M, Faulhaber J, Schiffelholz T, Romeo E, Di Michele F, Holsboer F, Rupprecht R. Lancel M, et al. J Pharmacol Exp Ther. 1997 Sep;282(3):1213-8. J Pharmacol Exp Ther. 1997. PMID: 9316828
Recent research in rats and humans has shown that exogenous progesterone evokes a sleep profile similar to that induced by agonistic modulators of gamma-aminobutyric acid(A) receptors, such as benzodiazepines. ...The sleep effects of a …
Recent research in rats and humans has shown that exogenous progesterone evokes a sleep profile similar to that induced by ago …
Targeting progesterone receptors in newborn males and females: From the animal model to a new perspective for the treatment of apnea of prematurity?
Bairam A, Boukari R, Joseph V. Bairam A, et al. Respir Physiol Neurobiol. 2019 May;263:55-61. doi: 10.1016/j.resp.2019.03.004. Epub 2019 Mar 14. Respir Physiol Neurobiol. 2019. PMID: 30880277 Review.
The steroid hormone progesterone is well-known for its role in neuroprotection, in the pre- and postnatal brain development, and is also recognized as a potent respiratory stimulant that reduces the frequency of sleep apnea in adult female subjects. Over the past fe …
The steroid hormone progesterone is well-known for its role in neuroprotection, in the pre- and postnatal brain development, and is a …
Overview of the Molecular Steps in Steroidogenesis of the GABAergic Neurosteroids Allopregnanolone and Pregnanolone.
Liang JJ, Rasmusson AM. Liang JJ, et al. Chronic Stress (Thousand Oaks). 2018 Dec 19;2:2470547018818555. doi: 10.1177/2470547018818555. eCollection 2018 Jan-Dec. Chronic Stress (Thousand Oaks). 2018. PMID: 32440589 Free PMC article. Review.
Allopregnanolone and pregnanolone equipotently facilitate the effects of gamma-amino-butyric acid (GABA) at GABA(A) receptors, and when sulfated, antagonize N-methyl-D-aspartate receptors. ...Given that these neurosteroids are synthesized de nov …
Allopregnanolone and pregnanolone equipotently facilitate the effects of gamma-amino-butyric acid (GABA) at G …
Neurosteroids: molecular mechanisms of action and psychopharmacological significance.
Rupprecht R, Hauser CA, Trapp T, Holsboer F. Rupprecht R, et al. J Steroid Biochem Mol Biol. 1996 Jan;56(1-6 Spec No):163-8. doi: 10.1016/0960-0760(95)00233-2. J Steroid Biochem Mol Biol. 1996. PMID: 8603037 Review.
The 3 alpha-hydroxy ring A-reduced pregnane steroids allopregnanolone and tetrahydrodeoxycorticosterone have been thought not to interact with intracellular receptors but enhance gamma-aminobutyric acid (GABA)-medicated chloride currents. ...The …
The 3 alpha-hydroxy ring A-reduced pregnane steroids allopregnanolone and tetrahydrodeoxycorticosterone have been thought not to inte …
Neuropsychopharmacological properties of neuroactive steroids.
Rupprecht R, Holsboer F. Rupprecht R, et al. Steroids. 1999 Jan-Feb;64(1-2):83-91. doi: 10.1016/s0039-128x(98)00101-9. Steroids. 1999. PMID: 10323676 Review.
The 3alpha-hydroxy ring A-reduced pregnane steroids allopregnanolone and tetrahydrodeoxycorticosterone have been thought not to interact with intracellular receptors, but enhance gamma-aminobutyric acid (GABA)-mediated chloride currents, whereas …
The 3alpha-hydroxy ring A-reduced pregnane steroids allopregnanolone and tetrahydrodeoxycorticosterone have been thought not to inter …
22 results