Synthesis, radioiodination and in vitro and in vivo sigma receptor studies of N-1-allyl-N -4-phenethylpiperazine analogs.
Lever SZ, Xu R, Fan KH, Fergason-Cantrell EA, Carmack TL, Watkinson LD, Lever JR.
Lever SZ, et al.
Nucl Med Biol. 2012 Apr;39(3):401-14. doi: 10.1016/j.nucmedbio.2011.10.001. Epub 2011 Dec 14.
Nucl Med Biol. 2012.
PMID: 22172395
INTRODUCTION: Sigma-1 (sigma(1)) receptor radioligands are useful for basic pharmacology studies and for imaging studies in neurology, psychiatry and oncology. We derived a hybrid structure, N-1-allyl-N -4-phenethylpiperazine, from known ligands TPCNE and SA4503 for use as …
INTRODUCTION: Sigma-1 (sigma(1)) receptor radioligands are useful for basic pharmacology studies and for imaging studies in neurology, psych …