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Enzymatically-derived oligo-carrageenans interact with alpha-Gal antibodies and Galectin-3.
Sokolova E, Jouanneau D, Chevenier A, Jam M, Desban N, Colas P, Ficko-Blean E, Michel G. Sokolova E, et al. Carbohydr Polym. 2024 Jan 15;324:121563. doi: 10.1016/j.carbpol.2023.121563. Epub 2023 Nov 6. Carbohydr Polym. 2024. PMID: 37985065
Carrageenans are linear sulfated galactans synthesized in the Gigartinales, Rhodophyceae species with a varied range of biological properties that are of value to the pharmaceutical and cosmetic sectors. ...Here we use specific endo-carrageenases, from the marine bacterium …
Carrageenans are linear sulfated galactans synthesized in the Gigartinales, Rhodophyceae species with a varied range of biological pr …
The structure of a family 110 glycoside hydrolase provides insight into the hydrolysis of alpha-1,3-galactosidic linkages in lambda-carrageenan and blood group antigens.
McGuire BE, Hettle AG, Vickers C, King DT, Vocadlo DJ, Boraston AB. McGuire BE, et al. J Biol Chem. 2020 Dec 25;295(52):18426-18435. doi: 10.1074/jbc.RA120.015776. Epub 2020 Oct 30. J Biol Chem. 2020. PMID: 33127644 Free PMC article.
Terminal Galalpha1-3Gal motifs are found as a defining feature of different blood group and tissue antigens, as well as the building block of the marine algal galactan lambda-carrageenan. The blood group B antigen and linear alpha-Gal epitope can be processed …
Terminal Galalpha1-3Gal motifs are found as a defining feature of different blood group and tissue antigens, as well as the building block o …
Structure-activity relationships of acid-hydrolyzed Carrageenans: Molecular modifications and anticancer activity in colorectal Cancer cells.
Lacerda ECM, Pedrosa LF, Bezerra FF, Mourão PAS, Araújo GM, Simões FR, Fabi JP. Lacerda ECM, et al. Int J Biol Macromol. 2026 Jan;339(Pt 1):149812. doi: 10.1016/j.ijbiomac.2025.149812. Epub 2025 Dec 22. Int J Biol Macromol. 2026. PMID: 41443447
Investigating the relationship between carrageenan structure and biological effects is essential to understanding how carrageenans may affect cancer cells. ...FTIR and NMR structural analyses identified beta-Gal4SO(4) and 3,6-anhydro-alpha-Gal (DA) uni …
Investigating the relationship between carrageenan structure and biological effects is essential to understanding how carrageenans …
The Role of Carrageenan in Inflammatory Bowel Diseases and Allergic Reactions: Where Do We Stand?
Borsani B, De Santis R, Perico V, Penagini F, Pendezza E, Dilillo D, Bosetti A, Zuccotti GV, D'Auria E. Borsani B, et al. Nutrients. 2021 Sep 27;13(10):3402. doi: 10.3390/nu13103402. Nutrients. 2021. PMID: 34684400 Free PMC article. Review.
Moreover, specific IgE to the oligosaccharide alpha-Gal has been associated with allergic reactions commonly referred to as the "alpha-Gal syndrome". This review aims to discuss the role of carrageenan in inflammatory bowel diseases and allergic …
Moreover, specific IgE to the oligosaccharide alpha-Gal has been associated with allergic reactions commonly referred to as th …