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Tick bites, IgE to galactose-alpha-1,3-galactose and urticarial or anaphylactic reactions to mammalian meat: The alpha-gal syndrome.
Wilson JM, Erickson L, Levin M, Ailsworth SM, Commins SP, Platts-Mills TAE. Wilson JM, et al. Allergy. 2024 Jun;79(6):1440-1454. doi: 10.1111/all.16003. Epub 2024 Jan 9. Allergy. 2024. PMID: 38193233 Free PMC article. Review.
The syndrome, mediated by IgE antibodies against the oligosaccharide galactose-alpha-1,3-galactose (alpha-gal), can also involve reactions to visceral organs, dairy, gelatin and other products, including medications sourced from non-primate mammals. ...Reacti …
The syndrome, mediated by IgE antibodies against the oligosaccharide galactose-alpha-1,3-galactose (alpha-gal), can also invol …
Ingestion of mammalian meat and alpha-gal allergy: Clinical relevance in primary care.
Mabelane T, Ogunbanjo GA. Mabelane T, et al. Afr J Prim Health Care Fam Med. 2019 Apr 29;11(1):e1-e5. doi: 10.4102/phcfm.v11i1.1901. Afr J Prim Health Care Fam Med. 2019. PMID: 31038347 Free PMC article. Review.
Diagnosis is based on a history of reaction to mammalian meats (especially to fatty portions or organs) and serum specific alpha-gal antibodies. The main management of the alpha-gal allergy is avoidance of red meat and in mild reactions t …
Diagnosis is based on a history of reaction to mammalian meats (especially to fatty portions or organs) and serum specific alpha …
Alpha-Gal Syndrome and Cardiac Surgery.
Zvara J, Smith AL, Mazzeffi MA, Kleiman AM, Tanaka K, Smith AR, Wilson JM, McNeil JS. Zvara J, et al. J Cardiothorac Vasc Anesth. 2024 Nov;38(11):2805-2811. doi: 10.1053/j.jvca.2024.07.035. Epub 2024 Jul 22. J Cardiothorac Vasc Anesth. 2024. PMID: 39097488 Review.
Galactose-alpha-1,3-galactose (alpha-gal) is a carbohydrate expressed by all mammals except for humans and certain old-world primates. ...In the late 2000s, an association between tick bites and the development of immunoglobulin E antibodies to the alpha-g …
Galactose-alpha-1,3-galactose (alpha-gal) is a carbohydrate expressed by all mammals except for humans and certain old-world p …
Tick bite-induced alpha-gal syndrome and immunologic responses in an alpha-gal deficient murine model.
Sharma SR, Choudhary SK, Vorobiov J, Commins SP, Karim S. Sharma SR, et al. Front Immunol. 2024 Feb 8;14:1336883. doi: 10.3389/fimmu.2023.1336883. eCollection 2023. Front Immunol. 2024. PMID: 38390396 Free PMC article.
INTRODUCTION: Alpha-Gal Syndrome (AGS) is a delayed allergic reaction due to specific IgE antibodies targeting galactose-alpha-1,3-galactose (alpha-gal), a carbohydrate found in red meat. ...Pork challenge in Am. americanum -sensitized mice led …
INTRODUCTION: Alpha-Gal Syndrome (AGS) is a delayed allergic reaction due to specific IgE antibodies targeting galactose-alpha …
Alpha-gal Syndrome - A Case Report of Tick-Borne Anaphylactic Shock.
Müller J, Radej J, Kriz M, Hunkova E, Kasparek J, Matejovic M. Müller J, et al. Eur J Case Rep Intern Med. 2023 Jun 19;10(7):003939. doi: 10.12890/2023_003939. eCollection 2023. Eur J Case Rep Intern Med. 2023. PMID: 37455690 Free PMC article.
Alpha-gal syndrome is a relatively new, but increasingly recognised health issue. We propose that alpha-gal syndrome should be considered in the differential diagnosis of vasoplegic shock of unclear aetiology even in the absence of typical allergic sym …
Alpha-gal syndrome is a relatively new, but increasingly recognised health issue. We propose that alpha-gal synd …
Tick Bites Induce Anti-alpha-Gal Antibodies in Dogs.
Hodžić A, Mateos-Hernández L, Leschnik M, Alberdi P, Rego ROM, Contreras M, Villar M, de la Fuente J, Cabezas-Cruz A, Duscher GG. Hodžić A, et al. Vaccines (Basel). 2019 Sep 15;7(3):114. doi: 10.3390/vaccines7030114. Vaccines (Basel). 2019. PMID: 31540167 Free PMC article.
Apart from being involved in the hyperacute organ rejection in humans, anti-alpha-Gal antibodies have shown a protective effect against some pathogenic agents and an implication in the recently recognized tick-induced mammalian meat allergy. ...However …
Apart from being involved in the hyperacute organ rejection in humans, anti-alpha-Gal antibodies have shown a protectiv …
Tick bite-induced Alpha-Gal Syndrome and Immunologic Responses in an Alpha-Gal Deficient Murine Model.
Sharma SR, Choudhary SK, Vorobiov J, Commins SP, Karim S. Sharma SR, et al. bioRxiv [Preprint]. 2023 Nov 13:2023.11.09.566281. doi: 10.1101/2023.11.09.566281. bioRxiv. 2023. Update in: Front Immunol. 2024 Feb 08;14:1336883. doi: 10.3389/fimmu.2023.1336883. PMID: 38014105 Free PMC article. Updated. Preprint.
INTRODUCTION: Alpha-Gal Syndrome (AGS) is a delayed allergic reaction due to specific IgE antibodies targeting galactose-alpha-1,3-galactose (alpha-gal), a carbohydrate found in red meat. ...Previous research has established a connection between …
INTRODUCTION: Alpha-Gal Syndrome (AGS) is a delayed allergic reaction due to specific IgE antibodies targeting galactose-alpha …
Anaphylaxis to the carbohydrate side chain alpha-gal.
Platts-Mills TA, Schuyler AJ, Tripathi A, Commins SP. Platts-Mills TA, et al. Immunol Allergy Clin North Am. 2015 May;35(2):247-60. doi: 10.1016/j.iac.2015.01.009. Epub 2015 Mar 6. Immunol Allergy Clin North Am. 2015. PMID: 25841549 Free PMC article. Review.
Investigation of pretreatment sera established that they contained immunoglobulin (Ig) E against the oligosaccharide galactose-alpha-1,3-galactose (alpha-gal), which is present on the Fab of cetuximab. Alpha-gal is a blood group substance of nonprimate …
Investigation of pretreatment sera established that they contained immunoglobulin (Ig) E against the oligosaccharide galactose-alpha-1,3-gal …
Tick salivary gland extract induces alpha-gal syndrome in alpha-gal deficient mice.
Choudhary SK, Karim S, Iweala OI, Choudhary S, Crispell G, Sharma SR, Addison CT, Kulis M, Herrin BH, Little SE, Commins SP. Choudhary SK, et al. Immun Inflamm Dis. 2021 Sep;9(3):984-990. doi: 10.1002/iid3.457. Epub 2021 May 25. Immun Inflamm Dis. 2021. PMID: 34034363 Free PMC article.
INTRODUCTION: Alpha-gal syndrome (AGS) is characterized by delayed hypersensitivity to non-primate mammalian meat in people having specific immunoglobulin E (sIgE) to the oligosaccharide galactose-alpha-1,3-galactose. AGS has been linked to tick bites from Am …
INTRODUCTION: Alpha-gal syndrome (AGS) is characterized by delayed hypersensitivity to non-primate mammalian meat in pe …
Alpha gal specific IgE positivity due to tick bites and red meat allergy: the first case report in Turkey.
Keleş Ş, Gündüz M. Keleş Ş, et al. Turk J Pediatr. 2019;61(4):615-617. doi: 10.24953/turkjped.2019.04.023. Turk J Pediatr. 2019. PMID: 31990484 Free article.
Keles S, Gunduz M. Alpha gal specific IgE positivity due to tick bites and red meat allergy: the first case report in Turkey. ...Galactose-alpha-1,3-galactose is a carbohydrate moiety found in the cell membranes of many organisms, commonly known as …
Keles S, Gunduz M. Alpha gal specific IgE positivity due to tick bites and red meat allergy: the first case report in T …
24 results